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Social and Behavioral Sciences Commons

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Theses and Dissertations

University of South Carolina

2019

Fragile X Syndrome

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Full-Text Articles in Social and Behavioral Sciences

Predicting Change In Autism Symptomatology In Young Children At Risk For Autism Spectrum Disorder: Fragile X Syndrome, Down Syndrome And Non-Syndromic Asd, Kelly Elizabeth Caravella Oct 2019

Predicting Change In Autism Symptomatology In Young Children At Risk For Autism Spectrum Disorder: Fragile X Syndrome, Down Syndrome And Non-Syndromic Asd, Kelly Elizabeth Caravella

Theses and Dissertations

This dissertation is comprised of two manuscripts which examine the longitudinal development of autism symptomatology in young children at risk for developing autism spectrum disorder (ASD); individuals with Fragile x syndrome (FXS) and Down syndrome (DS). The first study is a within group analysis of the longitudinal development of ASD symptomatology in young children with FXS, and how diagnostic stability, language and non-verbal cognitive functioning may predict these trajectories. This paper provides insight into ASD diagnostic stability patterns within FXS, and how symptoms change over time across these groups. The second paper will extend this work by presenting a pilot …


Early Behavioral And Physiological Markers Of Social Anxiety In Fragile X Syndrome, Conner J. Black Oct 2019

Early Behavioral And Physiological Markers Of Social Anxiety In Fragile X Syndrome, Conner J. Black

Theses and Dissertations

Background: Social Anxiety is diagnosed in approximately 10% of neurotypical children. If left untreated, negative outcomes are highly prevalent later in life. Thus, understanding the earliest features of social anxiety can help to mitigate detrimental outcomes. Fragile X Syndrome, which has a high prevalence of social anxiety, is a genetic syndrome which creates a unique opportunity to study the earliest predictors of social anxiety before formal diagnosis. Fragile X Syndrome presents with intellectual disability and an increased prevalence of maladaptive behaviors. The current study utilized a bio-behavioral approach to study the earliest marker of social anxiety in 12- month-old infants …