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Full-Text Articles in Social and Behavioral Sciences
Development And Characterization Of A High-Resolution Microspect System For Small-Animal Imaging, Yujin Qi, Benjamin Tsui, Yuchuan Wang, Brian Yoder, R Wojcik, S Majewski, A G Weisenberger
Development And Characterization Of A High-Resolution Microspect System For Small-Animal Imaging, Yujin Qi, Benjamin Tsui, Yuchuan Wang, Brian Yoder, R Wojcik, S Majewski, A G Weisenberger
Faculty of Engineering and Information Sciences - Papers: Part A
We developed a high-resolution microSPECT system and investigated its performance characteristics for small animal imaging. The microSPECT system consists of a stationary compact gamma camera with interchangeable pinhole and parallel-hole collimators and vertical object rotation mechanism. The modular camera is based on a pixellated NaI(Tl) crystal array with 1.2 mm pixel size and 1.4 mm pixel pitch coupled to a 5” diameter Hamamatsu R3292 PSPMT. The pinhole collimator has a 10cm focal length fitted with keel-edge pinhole apertures with diameters of 1.0, 1.5 and 2.0 mm. The system performance was characterized by the measurements of the point source response function …
Optimized Collimator Designs For Small Animal Spect Imaging With A Compact Gamma Camera, Yujin Qi
Optimized Collimator Designs For Small Animal Spect Imaging With A Compact Gamma Camera, Yujin Qi
Faculty of Engineering and Information Sciences - Papers: Part A
The aim of this study to design optimized pinhole and parallel-hole collimators for the development of a high-resolution microSPECT system using a compact pixelleted scintillation detector. The detector has a field-of-view of 11 cm with pixellated crystal elements of 1.0 mm pixel size and 1.12 mm pixel pitch. The relative resolution and sensitivity advantages of pinhole and parallel-hole collimators for mice and rats imaging were investigated using analytic formulations and Monte Carlo simulations. The optimized collimator designs were obtained by maximizing the system detection efficiency for a given object resolution. The collimator designs were optimized for 140 keV incident gamma …