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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
An Exploration Of The Wheel-Induced Feeding-Suppression, Stephen Benjamin Peckham
An Exploration Of The Wheel-Induced Feeding-Suppression, Stephen Benjamin Peckham
Theses and Dissertations (Comprehensive)
Anorexia nervosa is an enigmatic human condition typified by food-restriction that is often accompanied by extensive exercise. This has been modeled in rats in the wheel-induced feeding-suppression (WIFS) model. In this model, animals are given access to a running-wheel, which induces a volitional drop in food-consumption. Short periods of wheel access have induced a feeding-suppression which is effectively reversed by chlorpromazine administration (Adams et al., 2009). Recent attempts at replicating Adams et al.’s (2009) feeding-suppression have, however, been unsuccessful (Peckham et al., 2013). These attempts raised questions as to whether or not the existing methodology is most effective at suppressing …
A Bittersweet Investigation Of Availability And Nutritive Value As Determinants Of Volitional Sucrose Consumption, Milan D. Valyear
A Bittersweet Investigation Of Availability And Nutritive Value As Determinants Of Volitional Sucrose Consumption, Milan D. Valyear
Theses and Dissertations (Comprehensive)
Rats given ~24 h access to a 4% sucrose solution every 3rd day (E3DA) consume about 100 g more solution than rats with continuous, everyday access (EDA). Under the same EDA-E3DA conditions rats will consume similar amounts of a more concentrated 8 or 16% sucrose solutions (Eikelboom, Hewitt, & Adams, Unpublished). It maybe that with these more concentrated solutions rats hit a satiety limit that prevents a difference between EDA and E3DA consumption from being evident. Experiment 1 was conducted to investigate the effect of adding quinine to 4% and 8% sucrose solutions with the intention of reducing consumption …
The Effects Of Housing Manipulations On Wheel Running, Feeding And Body Weight In Female Rats, Angela Mastroianni
The Effects Of Housing Manipulations On Wheel Running, Feeding And Body Weight In Female Rats, Angela Mastroianni
Theses and Dissertations (Comprehensive)
Providing rats with running wheel access results in a short-term reduction in feeding and body weight relative to controls; known as the wheel-induced feeding suppression (WIFS). WIFS may parallel aspects of anorexia nervosa, an eating disorder that mostly affects females. Yet, most studies of WIFS and related models use male rats. The present study included female and male rats, where half were given wheel access to measure effects on feeding and body weight. Replication 1 females and Replication 2 males were in unisex housing. Replication 3 males and females were housed in same room. Rats were individually (IH) or pair …