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Social and Behavioral Sciences Commons

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Wayne State University

Wayne State University Theses

Theses/Dissertations

Depression

Publication Year

Articles 1 - 4 of 4

Full-Text Articles in Social and Behavioral Sciences

Effectiveness Of Different Corticosterone Administration Methods To Alter Corticosterone Levels In Serum And Depressive-Like Behavior In Female Rats, Jennifer Marie Kott Jan 2015

Effectiveness Of Different Corticosterone Administration Methods To Alter Corticosterone Levels In Serum And Depressive-Like Behavior In Female Rats, Jennifer Marie Kott

Wayne State University Theses

There is wide variation in the current literature on rodent models of high levels of chronic stress. This study aims to reduce these discrepancies by investigating the effects of 3 different administration methods of corticosterone (CORT; the endogenous stress hormone in rodents) and the differential effects it has in the female sex. The majority of studies utilize male rodents, while research in female rodents is largely under-investigated. This study will utilize female rats and 3 different administration routes: a) subcutaneous implantation of a CORT pellet, b) CORT in the drinking water, and c) CORT by a daily subcutaneous injection, and …


The Role Of World View Changes In The Longitudinal Associations Between Depression And Ptsd Symptoms And Later Sexual Problems, Erin Paige Mason Jan 2013

The Role Of World View Changes In The Longitudinal Associations Between Depression And Ptsd Symptoms And Later Sexual Problems, Erin Paige Mason

Wayne State University Theses

Childhood sexual abuse (CSA) is a risk factor for the development of depression and posttraumatic stress disorder (PTSD) symptoms, as well as sexual problems. Additionally, previous research supports a relationship between symptoms of depression and PTSD and sexual problems in both sexually abused and non-abused samples. There has been little attempt, however, to explain the mechanisms responsible for this relationship. The current study proposed that abuse-related changes in world views might be one such mechanism and examined whether world view changes mediate longitudinal associations between depression and PTSD symptoms and sexual problems (sexual concerns, dysfunctional sexual behavior, and risky sexual …


Antidepressant Medications And Cognitive Functioning In Major Depressive Disorder, Rachel Kay Jan 2013

Antidepressant Medications And Cognitive Functioning In Major Depressive Disorder, Rachel Kay

Wayne State University Theses

Individuals with Major Depressive Disorder (MDD) frequently experience cognitive decrements in addition to mood impairments. Ironically, antidepressant medications used to treat depression may have adverse effects on cognitive functioning. It is imperative to understand the relative cognitive costs of antidepressants when considering the treatment of MDD patients. Furthermore, observational studies of depression are challenged by problems of systematically confounded variables. Researchers are often faced with difficulties in managing this issue and opt to either ignore the problem, alter their sample, or use inappropriate statistical methods (e.g., Analysis of Covariance) due to a limited understanding of acceptable solutions. It is important …


Ethnicity, Culture, And Mental Health Among College Students Of Middle Eastern Heritage, Hasti Ashtiani Raveau Jan 2013

Ethnicity, Culture, And Mental Health Among College Students Of Middle Eastern Heritage, Hasti Ashtiani Raveau

Wayne State University Theses

Depression is a significant mental health issue in American college students. However, as is the case for other minority students, this topic has been little studied in students of Middle Eastern background. Stigma and negative attitudes toward seeking mental health services are a big part of Middle Eastern culture, which reduces the chances that this population will seek treatment when they need it. In addition, it is important to study the relationship between ethnic identity and psychological functioning, because ethnic identity could serve as a protective factor against depression in persons of Middle Eastern descent. A strong cultural identity is …