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Social and Behavioral Sciences Commons

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Full-Text Articles in Social and Behavioral Sciences

Polysaccharopeptide Enhances The Anticancer Activity Of Doxorubicin And Etoposide On Human Breast Cancer Cells Zr-75-30, Jennifer Man-Fan Wan, Wai Hung Sit, Jimmy Chun Yu Louie Jan 2008

Polysaccharopeptide Enhances The Anticancer Activity Of Doxorubicin And Etoposide On Human Breast Cancer Cells Zr-75-30, Jennifer Man-Fan Wan, Wai Hung Sit, Jimmy Chun Yu Louie

Faculty of Health and Behavioural Sciences - Papers (Archive)

In search of natural bioactive microbial compounds with adjuvant properties, we have previously showed that the polysaccharopeptide (PSP), isolated from Chinese medicinal mushroom Coriolus versicolor, was able to enhance the cytotoxicity of certain S-phase targeted-drugs on human leukemic HL-60 cells via some cell-cycle and apoptotic-dependent pathways. The present study aimed to investigate whether the synergism of mechanisms of PSP with certain chemotherapeutic drugs also applies to human breast cancer. PSP treatment enhanced the cytotoxicity of doxorubicin (Doxo), etoposide (VP-16) but not cytarabine (Ara-C). Bivariate bromodeoxyuridine (BrdUrd)/DNA flow cytometry analysis estimated a longer DNA synthesis time (Ts) for the PSP treated …


Evaluating The Impact Of The Environment On The Physical Activity Levels Of People With Dementia In Aged Care Facilities, Loren Devries, Victoria Traynor, Nancy Humpel Jan 2008

Evaluating The Impact Of The Environment On The Physical Activity Levels Of People With Dementia In Aged Care Facilities, Loren Devries, Victoria Traynor, Nancy Humpel

Faculty of Health and Behavioural Sciences - Papers (Archive)

To evaluate the impact of the environment on the physical activity levels of people with dementia living in residential aged care facilities


Antimycobacterial Activity Of Cinnamate-Based Esters Of The Triterpenes Betulinic, Oleanolic And Ursolic Acids, Tanud Tanachatchairatana, John B. Bremner, Ratchanaporn Chokchaisiri, Apichart Suksamrarn Jan 2008

Antimycobacterial Activity Of Cinnamate-Based Esters Of The Triterpenes Betulinic, Oleanolic And Ursolic Acids, Tanud Tanachatchairatana, John B. Bremner, Ratchanaporn Chokchaisiri, Apichart Suksamrarn

Faculty of Science - Papers (Archive)

Betulinic acid, oleanolic acid and ursolic acid have been modified at the C-3 position to cinnamate-based esters and in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Ra has been determined. The results indicated that modification of the parent structures of betulinic acid, oleanolic acid and ursolic acid to the p-coumarate and, in the case of the latter two triterpenes, the ferulate ester analogues resulted in high antimycobacterial activity. Structure–activity relationships within the lupane, oleanane and ursane analogues and between these triterpenes are discussed.


Ict Devices As Ubiquitous Tools For Information Seeking Activity, Joseph A. Meloche, Helen M. Hasan Jan 2008

Ict Devices As Ubiquitous Tools For Information Seeking Activity, Joseph A. Meloche, Helen M. Hasan

Faculty of Commerce - Papers (Archive)

This paper investigates the use of current and developing ubiquitous digital devices and the way that they impact on, and are integrated into, use by groups within the community for information seeking. Three cases are presented involving ubiquitous use of the mobile phone, USB memory devices, and a wireless groupware system. The study considers the need for ongoing research to inform, direct and study the innovative use, appropriation and development of such tools. The primary methodological framework that is applied is activity theory, as it allows dasiatoolpsila to be examined in light of purposeful activity in the context of their …


Do Australian Primary School Environments Affect Children's Playground Physical Activity Levels?, Anne-Maree Parrish, Donald Iverson, Kenneth Russell, Heather Yeatman Jan 2008

Do Australian Primary School Environments Affect Children's Playground Physical Activity Levels?, Anne-Maree Parrish, Donald Iverson, Kenneth Russell, Heather Yeatman

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.