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Full-Text Articles in Social and Behavioral Sciences
Mid-Holocene Age Obtained For Nested Diamond Pattern Petroglyph In The Billasurgam Cave Complex, Kurnool District, Southern India, Paul S.C Tacon, Nicole Boivin, Michael Petraglia, James Blinkhorn, Allan Chivas, Richard G. Roberts, David Fink, Thomas Higham, Peter Ditchfield, Ravi Korisettar, Jian-Xin Zhao
Mid-Holocene Age Obtained For Nested Diamond Pattern Petroglyph In The Billasurgam Cave Complex, Kurnool District, Southern India, Paul S.C Tacon, Nicole Boivin, Michael Petraglia, James Blinkhorn, Allan Chivas, Richard G. Roberts, David Fink, Thomas Higham, Peter Ditchfield, Ravi Korisettar, Jian-Xin Zhao
Faculty of Science, Medicine and Health - Papers: part A
India has one of the world's largest and most significant bodies of rock paintings and engravings, yet not a single rock art site or image has been directly and accurately dated using radiometric techniques. Here we report on results from the Billasurgam Cave complex near Kurnool in southern India. Although this cave complex has been investigated archaeologically since the late 1800s, it was not until 2008 that a large petroglyph, consisting of the remains of three nested diamond designs on a stalactite, was noted. In order to determine if this petroglyph had been made recently, flowstone was sampled from on …
Coastal Evolution On Volcanic Oceanic Islands: A Complex Interplay Between Volcanism, Erosion, Sedimentation, Sea-Level Change And Biogenic Production, Ricardo S. Ramalho, Rui Quartau, Alan S. Trenhaile, Neil C. Mitchell, Colin D. Woodroffe, Sergio P. Avila
Coastal Evolution On Volcanic Oceanic Islands: A Complex Interplay Between Volcanism, Erosion, Sedimentation, Sea-Level Change And Biogenic Production, Ricardo S. Ramalho, Rui Quartau, Alan S. Trenhaile, Neil C. Mitchell, Colin D. Woodroffe, Sergio P. Avila
Faculty of Science, Medicine and Health - Papers: part A
The growth and decay of oceanic hotspot volcanoes are intrinsically related to a competition between volcanic construction and erosive destruction, and coastlines are at the forefront of such confrontation. In this paper, we review the several mechanisms that interact and contribute to the development of coastlines on oceanic island volcanoes, and how these processes evolve throughout the islands' lifetime. Volcanic constructional processes dominate during the emergent island and subaerial shield-building stages. During the emergent island stage, surtseyan activity prevails and hydroclastic and pyroclastic structures form; these structures are generally ephemeral because they can be rapidly obliterated by marine erosion. With …
Polycyclic Evolution Of Camboriú Complex Migmatites, Santa Catarina, Southern Brazil: Integrated Hf Isotopic And U-Pb Age Zircon Evidence Of Episodic Reworking Of A Mesoarchean Juvenile Crust, Miguel Angelo Stipp Basei, Mario Da Costa Campos Neto, Angela Pacheco Lopes, Allen Phillip Nutman, Dunyi Liu, Kei Sato
Polycyclic Evolution Of Camboriú Complex Migmatites, Santa Catarina, Southern Brazil: Integrated Hf Isotopic And U-Pb Age Zircon Evidence Of Episodic Reworking Of A Mesoarchean Juvenile Crust, Miguel Angelo Stipp Basei, Mario Da Costa Campos Neto, Angela Pacheco Lopes, Allen Phillip Nutman, Dunyi Liu, Kei Sato
Faculty of Science, Medicine and Health - Papers: part A
The Camboriú Complex is the only gneissic-migmatitic inlier within the Neoproterozoic Brusque Group supracrustal rocks, in the northernmost part of the Dom Feliciano Belt, southern Brazil. It comprises the Morro do Boi migmatites and the diatexitic Ponta do Cabeço Granite. Zircon U-Pb dating of migmatites and associated granitic neosomes shows that crustal evolution started in the Paleo- Mesoarchean (3.3-3.0 Ga), continued with events through the Neoarchean and Paleoproterozoic and ended in the Neoproterozoic (0.64-0.61 Ga). Integration of zircon Hf isotopic data and U-Pb ages indicate that juvenile crustal accretion was restricted to the Archean and that afterwards intracrustal reworking predominated. …
Expression Of Proteins Within The Nogo Receptor Complex Are Altered In The Dorsolateral Prefrontal Cortex In Schizophrenia, J Andrews, K Newell, F Fernandez
Expression Of Proteins Within The Nogo Receptor Complex Are Altered In The Dorsolateral Prefrontal Cortex In Schizophrenia, J Andrews, K Newell, F Fernandez
Faculty of Science, Medicine and Health - Papers: part A
No abstract provided.
The Itsaq Gneiss Complex Of Greenland: Episodic 3900 To 3660 Ma Juvenile Crust Formation And Recycling In The 3660 To 3600 Ma Isukasian Orogeny, Allen P. Nutman, Vickie C. Bennett, Clark R. L Friend, Hiroshi Hidaka, Keewook Yi, Seung Ryeol Lee, Tomoyuki Kamiichi
The Itsaq Gneiss Complex Of Greenland: Episodic 3900 To 3660 Ma Juvenile Crust Formation And Recycling In The 3660 To 3600 Ma Isukasian Orogeny, Allen P. Nutman, Vickie C. Bennett, Clark R. L Friend, Hiroshi Hidaka, Keewook Yi, Seung Ryeol Lee, Tomoyuki Kamiichi
Faculty of Science, Medicine and Health - Papers: part A
From the 3000 km2 Eoarchean Itsaq Gneiss Complex (IGC) of Greenland, zircon U-Pb dating of numerous meta-granitoid and orthogneiss samples is integrated with geologic observations, whole rock geochemistry and a strategic subset of zircon Hf and whole rock Nd isotopic measurements. This shows that there are multiple episodes of TTG suite formation from ∼3890 to 3660 Ma, characterized by zircon initial εHf≈0 and whole rock initial εNd of > +2. These rocks mostly have geochemical signatures of partial melting of eclogitized mafic sources, with a subset of high magnesian, low silica rocks indicating fusion by fluid fluxing of upper mantle sources. …
Theoretical Study On The Ring-Opening Reactions Of Cyclopropenes Mediated By A Aui Complex, Nasir Ahmad Rajabi, Mona Jalali Atashgah, Rasool Babaahmadi, Christopher Hyland, Alireza Ariafard
Theoretical Study On The Ring-Opening Reactions Of Cyclopropenes Mediated By A Aui Complex, Nasir Ahmad Rajabi, Mona Jalali Atashgah, Rasool Babaahmadi, Christopher Hyland, Alireza Ariafard
Faculty of Science, Medicine and Health - Papers: part A
DFT calculations have been carried out in order to rationalize and predict the ring-opening regioselectivity of substituted cyclopropenes in the presence of gold(I) catalysts. It has been shown that the regioselectivity of these ring-opening processes is driven by the relative π-donor ability of the substituents on the cyclopropene double bond (C1 and C2). A stronger π-donor substituent at C2 favors Au(I)-induced polarization of the double bond toward C1, resulting in preferential breaking of the C1–C3 bond. An excellent correlation between ΔE and the difference in the C1–C2 p(π) orbital population was observed for a broad range of substituents, providing a …
Proofreading Exonuclease On A Tether: The Complex Between The E. Coli Dna Polymerase Iii Subunits Α, Ε, Θ And Β Reveals A Highly Flexible Arrangement Of The Proofreading Domain, Kiyoshi Ozawa, Nicholas P. Horan, Andrew Robinson, Hiromasa Yagi, Flynn R. Hill, Slobodan Jergic, Zhi-Qiang Xu, Karin V. Loscha, Nan Li, Moeava Tehei, Aaron J. Oakley, Gottfried Otting, Thomas Huber, Nicholas E. Dixon
Proofreading Exonuclease On A Tether: The Complex Between The E. Coli Dna Polymerase Iii Subunits Α, Ε, Θ And Β Reveals A Highly Flexible Arrangement Of The Proofreading Domain, Kiyoshi Ozawa, Nicholas P. Horan, Andrew Robinson, Hiromasa Yagi, Flynn R. Hill, Slobodan Jergic, Zhi-Qiang Xu, Karin V. Loscha, Nan Li, Moeava Tehei, Aaron J. Oakley, Gottfried Otting, Thomas Huber, Nicholas E. Dixon
Faculty of Science, Medicine and Health - Papers: part A
A complex of the three (αεθ) core subunits and the β2 sliding clamp is responsible for DNA synthesis by Pol III, the Escherichia coli chromosomal DNA replicase. The 1.7 Å crystal structure of a complex between the PHP domain of α (polymerase) and the C-terminal segment of ε (proofreading exonuclease) subunits shows that ε is attached to α at a site far from the polymerase active site. Both α and ε contain clamp-binding motifs (CBMs) that interact simultaneously with β2 in the polymerization mode of DNA replication by Pol III. Strengthening of both CBMs enables isolation of stable αεθ:β2 complexes. …
The Shu Complex Interacts With Rad51 Through The Rad51 Paralogues Rad55-Rad57 To Mediate Error-Free Recombination, Stephen Godin, Adam Wier, Faiz Kabbinavar, Dominique S. Bratton-Palmer, Harshad Ghodke, Bennett Van Houten, Andrew P. Vandemark, Kara A. Bernstein
The Shu Complex Interacts With Rad51 Through The Rad51 Paralogues Rad55-Rad57 To Mediate Error-Free Recombination, Stephen Godin, Adam Wier, Faiz Kabbinavar, Dominique S. Bratton-Palmer, Harshad Ghodke, Bennett Van Houten, Andrew P. Vandemark, Kara A. Bernstein
Faculty of Science, Medicine and Health - Papers: part A
The Saccharomyces cerevisiae Shu complex, consisting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown mechanism. Recent structural analysis of two Shu proteins, Csm2 and Psy3, has revealed that these proteins are Rad51 paralogues and mediate DNA binding of this complex. We show in vitro that the Csm2-Psy3 heterodimer preferentially binds synthetic forked DNA or 3′-DNA overhang substrates resembling structures used during HR in vivo . We find that Csm2 interacts with Rad51 and the Rad51 paralogues, the Rad55-Rad57 heterodimer and that the Shu complex functions in the same epistasis group as Rad55-Rad57. Importantly, Csm2's …
Selective Depletion Of Alloreactive T Cells Leads To Long-Term Islet Allograft Survival Across A Major Histocompatibility Complex Mismatch In Diabetic Mice, Min Hu, J Wu, G Y. Zhang, Y M. Wang, D Watson, S Yi, W J. Hawthorne, P J. O'Connell, S I. Alexander
Selective Depletion Of Alloreactive T Cells Leads To Long-Term Islet Allograft Survival Across A Major Histocompatibility Complex Mismatch In Diabetic Mice, Min Hu, J Wu, G Y. Zhang, Y M. Wang, D Watson, S Yi, W J. Hawthorne, P J. O'Connell, S I. Alexander
Faculty of Science, Medicine and Health - Papers: part A
Islet cell transplantation as a therapy for type 1 diabetes has been limited by progressive graft loss. Significant immunosuppression including T-cell ablation has been used in an attempt to limit islet rejection. Here, we show that CD3+ lymphocytes depleted of alloreactive T cells selected from a mixed lymphocyte reaction (MLR), where responder BALB/c splenocytes stained with carboxyfluorescein succinimidyl ester (CFSE) were stimulated with irradiated C57BL/6 splenocytes for 5 days, infused into diabetic immunodeficient mice are capable of restoring a broad T-cell repertoire and specifically do not reject islet transplants from the strain (C57BL/6) used in the original depletion. These mice …
Complex Responses Of Intertidal Molluscan Embryos To A Warming And Acidifying Ocean In The Presence Of Uv Radiation, Andrew R. Davis, Daniel Coleman, Alison Broad, Maria Byrne, Symon A. Dworjanyn, Rachel Przeslawski
Complex Responses Of Intertidal Molluscan Embryos To A Warming And Acidifying Ocean In The Presence Of Uv Radiation, Andrew R. Davis, Daniel Coleman, Alison Broad, Maria Byrne, Symon A. Dworjanyn, Rachel Przeslawski
Faculty of Science, Medicine and Health - Papers: part A
Climate change and ocean acidification will expose marine organisms to synchronous multiple stressors, with early life stages being potentially most vulnerable to changing environmental conditions. We simultaneously exposed encapsulated molluscan embryos to three abiotic stressors—acidified conditions, elevated temperate, and solar UV radiation in large outdoor water tables in a multifactorial design. Solar UV radiation was modified with plastic filters, while levels of the other factors reflected IPCC predictions for near-future change. We quantified mortality and the rate of embryonic development for a mid-shore littorinid, Bembicium nanum, and low-shore opisthobranch, Dolabrifera brazieri. Outcomes were consistent for these model species with embryos …