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Full-Text Articles in Social and Behavioral Sciences
Automated Surface Sampling Of Lipids From Worn Contact Lenses Coupled With Tandem Mass Spectrometry, Simon H. Brown, Liam H. Huxtable, Mark D. P Willcox, Stephen J. Blanksby, Todd W. Mitchell
Automated Surface Sampling Of Lipids From Worn Contact Lenses Coupled With Tandem Mass Spectrometry, Simon H. Brown, Liam H. Huxtable, Mark D. P Willcox, Stephen J. Blanksby, Todd W. Mitchell
Faculty of Science, Medicine and Health - Papers: part A
The deposition of biological material (biofouling) onto polymeric contact lenses is thought to be a major contributor to lens discomfort and hence discontinuation of wear. We describe a method to characterize lipid deposits directly from worn contact lenses utilizing liquid extraction surface analysis coupled to tandem mass spectrometry (LESA-MS/MS). This technique effected facile and reproducible extraction of lipids from the contact lens surfaces and identified lipid molecular species representing all major classes present in human tear film. Our data show that LESA-MS/MS is a rapid and comprehensive technique for the characterization of lipid-related biofouling on polymer surfaces.
Direct Detection Of Additives And Degradation Products From Polymers By Liquid Extraction Surface Analysis Employing Chip-Based Nanospray Mass Spectrometry, Martin Paine, Phillip Barker, Shane A. Maclaughlin, Todd W. Mitchell, Stephen J. Blanksby
Direct Detection Of Additives And Degradation Products From Polymers By Liquid Extraction Surface Analysis Employing Chip-Based Nanospray Mass Spectrometry, Martin Paine, Phillip Barker, Shane A. Maclaughlin, Todd W. Mitchell, Stephen J. Blanksby
Faculty of Science - Papers (Archive)
Rationale: Polymer-based surface coatings in outdoor applications experience accelerated degradation due to exposure to solar radiation, oxygen and atmospheric pollutants. These deleterious agents cause undesirable changes to the polymers aesthetic and mechanical properties reducing its lifetime. The use of antioxidants such as hindered amine light stabilisers (HALS) retard these degradative processes, however, mechanisms for HALS action and polymer degradation are poorly understood. Methods: Detection of the hindered amine light stabiliser (HALS) TINUVIN®123 (bis (1-octyloxy-2,2,6,6-tetramethyl-4-piperidyl) sebacate) and the polymer degradation products directly from a polyester-based coil coating was achieved by liquid extraction surface analysis (LESA) coupled to a triple quadrupole QTRAP® …
Paint Spray Mass Spectrometry For The Detection Of Additives From Polymers On Conducting Surfaces, Martin R.L Paine, Philip J. Barker, Stephen J. Blanksby
Paint Spray Mass Spectrometry For The Detection Of Additives From Polymers On Conducting Surfaces, Martin R.L Paine, Philip J. Barker, Stephen J. Blanksby
Faculty of Science, Medicine and Health - Papers: part A
Paint Spray is developed as a direct sampling ionisation method for mass spectrometric analysis of additives in polymer-based surface coatings. The technique simply involves applying an external high voltage (5 kV) to the wetted sample placed in front of the mass spectrometer inlet and represents a much simpler ionisation technique compared to those currently available. The capabilities of Paint Spray are demonstrated herein with the detection of four commercially available hindered amine light stabilisers; TINUVIN® 770, TINUVIN® 292, TINUVIN® 123 and TINUVIN® 152 directly from thermoset polyester-based coil coatings. Paint Spray requires no sample preparation or pre-treatment and combined with …