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Full-Text Articles in Social and Behavioral Sciences
An Activity Theory Analysis Of A Case Of It-Driven Organisational Change, Wannapa Suratmethakul, Helen Hasan
An Activity Theory Analysis Of A Case Of It-Driven Organisational Change, Wannapa Suratmethakul, Helen Hasan
Faculty of Commerce - Papers (Archive)
The paper describes unexpected problems encountered in the automation of a scheduling process using an IT application already in use in other similar organisations. A grounded theory approach was used to collect and categorise data on the case. Activity Theory was then used to analyse the attempt by management to implement organisational change through the introduction of the system. The findings suggest that it is inadvisable to impose organisational change through the introduction of a complex IT system, particularly when this disrupts entrenched decision-making processes of the organisation.
Analysis Of The Mechanism By Which Calcium Negatively Regulates The Tyrosine Phosphorylation Cascade Associated With Sperm Capacitation, Mark Baker, Louise Hethrington, Heath W. Ecroyd, Shaun D. Roman, Robert J. Aitken
Analysis Of The Mechanism By Which Calcium Negatively Regulates The Tyrosine Phosphorylation Cascade Associated With Sperm Capacitation, Mark Baker, Louise Hethrington, Heath W. Ecroyd, Shaun D. Roman, Robert J. Aitken
Faculty of Science - Papers (Archive)
The capacitation of mammalian spermatozoa involves the activation of a cAMP-mediated signal transduction pathway that drives tyrosine phosphorylation via mechanisms that are unique to this cell type. Controversy surrounds the impact of extracellular calcium on this process, with positive and negative effects being recorded in independent publications. We clearly demonstrate that the presence of calcium in the external medium decreases tyrosine phosphorylation in both human and mouse spermatozoa. Under these conditions, a rise in intracellular pH was recorded, however, this event was not responsible for the observed changes in phosphotyrosine expression. Rather, the impact of calcium on tyrosine phosphorylation in …
Finite-Element Analysis To Determine Effect Of Monolimb Flexibility On Structural Strength And Interaction Between Residual Limb And Prosthetic Socket, Winson Lee, Ming Zhang, David A. Boone, Bill Contoyannis
Finite-Element Analysis To Determine Effect Of Monolimb Flexibility On Structural Strength And Interaction Between Residual Limb And Prosthetic Socket, Winson Lee, Ming Zhang, David A. Boone, Bill Contoyannis
Faculty of Engineering and Information Sciences - Papers: Part A
Monolimb refers to a kind of transtibial prostheses having the socket and shank molded into one piece of thermoplastic material. One of its characteristics is that the shank is made of a material that can deform during walking, which can simulate ankle joint motion to some extent. Changes in shank geometry can alter the stress distribution within the monolimb and at the residual limb-socket interface and, respectively, affect the deformability and structural integrity of the prosthesis and comfort perceived by amputees. This paper describes the development of a finite-element model for the study of the structural behavior of monolimbs with …