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Full-Text Articles in Social and Behavioral Sciences

The Effects Of Prenatal Alcohol Exposure On The Resting State Functional Brain Connectivity In A Sample Of Individuals With Fetal Alcohol Spectrum Disorder, Carlos I. Rodriguez Jul 2018

The Effects Of Prenatal Alcohol Exposure On The Resting State Functional Brain Connectivity In A Sample Of Individuals With Fetal Alcohol Spectrum Disorder, Carlos I. Rodriguez

Psychology ETDs

It is well established that alcohol exposure during prenatal development can lead to a heterogeneous and wide ranging set of morphological and neurobehavioral deficits that are collectively known as Fetal Alcohol Spectrum Disorders (FASDs). Previous neuroimaging research conducted on individuals with FASD has primarily employed graph-theoretical based analysis methods on functional imaging data to elucidate the impact of prenatal alcohol on brain connectivity. This study applied a widely used computational algorithm, group independent components analysis (gICA), to extract coherent sets of voxels that were correlated with one another as a measure of functional network connectivity (FNC) in a sample of …


Moderate Prenatal Alcohol Exposure Impairs Performance In An Object-Place-Paired-Associate Task, Lilliana May Sanchez Apr 2018

Moderate Prenatal Alcohol Exposure Impairs Performance In An Object-Place-Paired-Associate Task, Lilliana May Sanchez

Psychology ETDs

Memory impairments, including spatial and object processing, are often observed in individuals with Fetal Alcohol Spectrum Disorder. Much attention has been directed towards the hippocampus, which displays significant alterations after moderate prenatal alcohol exposure (PAE). In the present study, we tested a moderate PAE rat model in an object-place-paired-associate (OPPA) task, previously shown to require hippocampal processing. The OPPA task was composed of training rats to discriminate between an identical pair of objects presented in 180° opposite arms of a radial arm maze. Animals were given a total of 10 trials per day over 14 consecutive days of training and …