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Social and Behavioral Sciences Commons

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Full-Text Articles in Social and Behavioral Sciences

Efficacy Of Galcanezumab For Migraine Prevention In Patients With A Medical History Of Anxiety And/Or Depression: A Post Hoc Analysis Of The Phase 3, Randomized, Double-Blind, Placebo-Controlled Regain, And Pooled Evolve-1 And Evolve-2 Studies, Todd A. Smitherman, Gretchen E. Tietjen, Kory Schuh, Vladimir Skljarevski, Sarah Lipsius, Deborah N. D’Souza, Eric M. Pearlman Nov 2020

Efficacy Of Galcanezumab For Migraine Prevention In Patients With A Medical History Of Anxiety And/Or Depression: A Post Hoc Analysis Of The Phase 3, Randomized, Double-Blind, Placebo-Controlled Regain, And Pooled Evolve-1 And Evolve-2 Studies, Todd A. Smitherman, Gretchen E. Tietjen, Kory Schuh, Vladimir Skljarevski, Sarah Lipsius, Deborah N. D’Souza, Eric M. Pearlman

Faculty and Student Publications

© 2020 Eli Lilly and Company. Headache: The Journal of Head and Face Pain published by Wiley Periodicals LLC, on behalf of American Headache Society Objective: This post hoc analysis evaluated the efficacy of galcanezumab for the prevention of migraine in patients with and without comorbid anxiety and/or depression. Background: Patients with migraine have a higher risk of anxiety and/or depression. Given the high prevalence of psychiatric symptoms and their potential negative prognostic impact, determining the efficacy of migraine treatments in patients with these comorbidities is important. Methods: The results of 2 phase 3 episodic migraine studies of patients with …


Unanticipated Stressful And Rewarding Experiences Engage The Same Prefrontal Cortex And Ventral Tegmental Area Neuronal Populations, Alberto Del Arco, Junchol Park, Bita Moghaddam May 2020

Unanticipated Stressful And Rewarding Experiences Engage The Same Prefrontal Cortex And Ventral Tegmental Area Neuronal Populations, Alberto Del Arco, Junchol Park, Bita Moghaddam

Faculty and Student Publications

© 2020 Del Arco et al. Brain networks that mediate motivated behavior in the context of aversive and rewarding experiences involve the prefrontal cortex (PFC) and ventral tegmental area (VTA). Neurons in both regions are activated by stress and reward, and by learned cues that predict aversive or appetitive outcomes. Recent studies have proposed that separate neuronal populations and circuits in these regions encode learned aversive versus appetitive contexts. But how about the actual experience? Do the same or different PFC and VTA neurons encode unanticipated aversive and appetitive experiences? To address this, we recorded unit activity and local field …


Screening For Depression Among A Sample Of Us College Students Who Engage In Recreational Prescription Opioid Misuse, Robert E. Davis, Martha A. Bass, M. Allison Wade, Vinayak K. Nahar Jan 2020

Screening For Depression Among A Sample Of Us College Students Who Engage In Recreational Prescription Opioid Misuse, Robert E. Davis, Martha A. Bass, M. Allison Wade, Vinayak K. Nahar

Faculty and Student Publications

© 2020 The Author(s). Background: Among student populations, literature has identified associations between prescription opioid misuse and symptoms of depression such as hopelessness, sadness, and emotional pain. Thus far, existing literature has yet to investigate associations between prescription opioid misuse and depression using validated screening instruments for depression when exploring such associations. The purpose of this study was to utilize a validated screening tool to explore quantifiable presence of depression among college students who engage in recreational prescription opioid misuse (RPOM). Additionally, gender differences in depression and co-occurring substance use are examined. Methods: Students (n = 104) of a large …