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Full-Text Articles in Social and Behavioral Sciences
Physiological Correlates Of Affective Decision-Making In Anxiety And Depression, Louisa I. Thompson
Physiological Correlates Of Affective Decision-Making In Anxiety And Depression, Louisa I. Thompson
Dissertations, Theses, and Capstone Projects
Improving our understanding of cognitive and physiological profiles in anxiety and depression has the potential to reveal novel ways to target and improve treatments for these prevalent mental health conditions. The present study examined the impact of self-reported anxiety and depression symptoms on three established decision-making measures, the Iowa Gambling Task (IGT; Bechara, Damasio, Damasio, & Anderson, 1994), Balloon Analogue Risk Task (BART; Lejuez et al., 2002), and Game of Dice Task (GDT; Brand et al., 2005), in a diverse sample of 100 college students (age 18 to 35). Physiological measures of tonic heart rate variability and galvanic skin response …
Sex Differences In The Anxiety Effects Of Cannabinoids, Helen T. French
Sex Differences In The Anxiety Effects Of Cannabinoids, Helen T. French
Dissertations, Theses, and Capstone Projects
Aim: Anxiety disorders are twice as common among women, and those with anxiety disorders are 2-3 times more likely to have a substance abuse disorder than the general populace. However, little data exists on the sexually dimorphic effects of cannabinoids. In male humans and rodents, low acute doses of cannabinoids are anxiolytic while high and/or chronic doses are anxiogenic. In the dose response curve (DRC), we examined whether the biphasic effects of cannabinoids observed in males are also present in females. In the CB1R antagonism study, CP55,940-induced CB1R activation was antagonized via the CB1R-selective antagonist rimonabant to test the hypothesis …