Social and Behavioral Sciences Commons^™

Does The Apoe-Ε4 Allele Differentially Influence Cognition: A Longitudinal Investigation In Healthy Older Adults At Risk For Alzheimer’S Disease, Aditya Kulkarni

Dissertations, Theses, and Capstone Projects

Background: The apolipoprotein E (APOE) ε4 allele is the strongest susceptibility factor for sporadic, late-onset, Alzheimer’s disease (AD). However, not all persons who carry the ε4 allele show significant cognitive decline, and thus do not progress to dementia. The impact of the ε4 allele on memory decline has been documented primarily in populations already demonstrating cognitive impairment (i.e., those with mild cognitive impairment or dementia), with fewer investigations completed in baseline healthy older adults. Investigations of the ε4 allele and its influence on non-memory domains are also sparse in the literature. Furthermore, these cognitive investigations are typically cross-sectional and …

The Effects Of Music Therapy On Elderly Adults With Dementia, Jeante J. Jackson

Dissertations, Theses, and Capstone Projects

As people age, the brain is more susceptible to changes that diminish cognitive function. In recent years neuroscience has found convergent evidence between music therapy and brain architecture, as it has shown the generation of new connections in the brain or a reorganization and possible strengthening of existing connections already in the brain. However, the literature regarding music training’s effects on executive control, selective attention, and speech processing is lacking particularly when it comes to older populations.

This study investigated Verbal Working Memory, Visuospatial Attention and Task Initiation, and Auditory Selective Attention in a 91-year-old adult (B.P.) diagnosed with dementia. …

Neuroanatomy In Mild Cognitive Impairment: Relationship To Functional Skills, Treatment Expectancy, And Comorbid Depression, Sara Rushia

Dissertations, Theses, and Capstone Projects

Mild cognitive impairment (MCI) is a neurocognitive disorder defined by cognitive decline in older adults. Although MCI has been studied for decades, there remain important areas to be explored in order to adequately characterize aspects of this disorder that provide information valuable for possible interventions and disease progression to dementia, including a better understanding of the neuroanatomical variables relevant to this disorder. Such neuroanatomical variables include cortical thickness, hippocampal volume, and white matter hyperintensities (WMHs). This dissertation consists of three separate studies aimed at addressing gaps in the literature on MCI in relation to brain morphometrics and under-studied characteristics involved …

Occupational Depression In A Spanish-Speaking Sample: Associations With Cognitive Performance And Work-Life Characteristics, Bianchi Renzo, Guadalupe Manzano García, Maria Pilar Montanes, Emily A. Schonfeld, Irvin Sam Schonfeld

Publications and Research

This 386-participant study investigated the structural and psychometric properties of the Spanish version of the Occupational Depression Inventory (ODI). Exploratory structural equation modeling bifactor analysis revealed that the ODI meets the requirements for essential unidimensionality. Measurement invariance held across our sample and the English- and French-speaking samples used in the ODI’s initial validation study. Mokken scale analysis indicated that (a) the scalability of the instrument was strong, (b) no violations of monotonicity or local independence were present, and (c) invariant item ordering was sufficiently accurate. The ODI’s reliability was optimal. The ODI exhibited both convergent validity and discriminant validity vis-à-vis …

Occupational Depression, Cognitive Performance, And Task Appreciation: A Study Based On Raven’S Advanced Progressive Matrices, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

The Occupational Depression Inventory (ODI) was recently developed to assess depressive symptoms that individuals specifically attribute to their work. Research on the criterion validity of the instrument is still in its infancy. In this study, we examined whether the ODI predicted performance on, and appreciation of, a cognitively challenging test. In light of the link established between clinical depression and neuropsychological impairment, and considering that individuals with depressive symptoms are more likely to feel helpless under challenging circumstances, we hypothesized that occupational depression would be associated with poorer cognitive performance and a darkened appreciation of the task undertaken. We relied …

Memory Bias Toward Emotional Information In Burnout And Depression, Renzo Bianchi, Eric Laurent, Irvin Sam Schonfeld, Lucas M. Bietti, Eric Mayor

Publications and Research

A sample of 1015 educational staff members, exhibiting various levels of burnout and depressive symptoms, underwent a memory test involving incident encoding of positive and negative words and a free recall task. Burnout and depression were each found to be associated with increased recall of negative items and decreased recall of positive items. Results remained statistically significant when controlling for history of depressive disorders. Burnout and depression were not related to mistakes in the reported words, or to the overall number of recalled words. This study suggests that burnout and depression overlap in terms of memory biases toward emotional information.

Using Object-Choice Tasks To Investigate Sensory Perception In Sunda Pangolins (Manis Javanica), Joshua Dipaola

Theses and Dissertations

Pangolins are one of the most heavily poached, yet least understood mammals in the world. In this study, we used an object-choice task to assess the ecological relevance and use of sensory information in Sunda pangolin foraging behavior. This is the first controlled experiment on pangolin behavior to our knowledge.

Object Permanence In Asian Elephants (Elephas Maximus), Dalia Miller

Theses and Dissertations

This study investigated object permanence in Asian elephants (Elephas maximus) using visible and invisible test paradigms with single and multiple object displacements. Elephants were predicted to succeed, demonstrating a capacity for object permanence and for using vision in a cognitive task. Study outcomes supported these predictions.

Detecting Cognitive, Functional And Behavioral Response To Donepezil In Alzheimer’S Disease: The Role Of Attention Tasks, Clara Vila-Castelar

Dissertations, Theses, and Capstone Projects

Introduction: Cholinesterase Inhibitors (ChEIs) used in Alzheimer’s Disease (AD) have modest effects, heterogeneous treatment response, and it has been difficult to detect treatment response. The standard research and clinical outcome measure, the Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-Cog) aggregates multiple cognitive domains, and has limited sensitivity. We propose that because acetylcholine is directly linked to the cognitive domain of attention, and ChEIs increase available acetylcholine, measures of attention under high-load conditions could predict long-term cognitive, functional and behavioral response, and thus, unlike global measures, could be sensitive to treatment efficacy.

Method: We conducted a longitudinal, open label donepezil trial …

Interpretation Bias Toward Ambiguous Information In Burnout And Depression, Renzo Bianchi, Eric Laurent, Irvin Sam Schonfeld, Jay Verkuilen, Chantal Berna

Publications and Research

Burnout has been defined as a job-related syndrome combining pervasive fatigue and loss of motivation. In recent years, evidence has mounted that burnout may reflect a depressive condition. In this study, we expanded on past investigations of burnout-depression overlap by focusing on interpretation biases toward ambiguous information among the two entities. We conducted a web-based study involving 1056 participants (83% female; mean age: 42.87). Burnout symptoms were assessed with the Shirom-Melamed Burnout Measure and depressive symptoms with the PHQ-9. The Ambiguous Scenarios Test (AST), a measure of interpretation bias validated among dysphoric individuals, was the outcome of interest. The AST …

Syntax And Semantics Of Perceptual Representation, James K. Quilty-Dunn

Dissertations, Theses, and Capstone Projects

This dissertation is a defense of perceptual pluralism, the thesis that perceptual systems deliver multiple types of representations including those used in thought. In particular, it argues that perceptual systems output iconic (i.e., image-like, analog) representations as well as discursive (i.e., language-like, digital) states. A central thesis is that perceptual representations of objects are propositional and composed of concepts. It also develops a compositional syntax of iconic representation called the coordination model, according to which icons are sets of primitive parts, each of which determines values along multiple analog feature dimensions simultaneously. The dissertation supports the conclusion that perceptual …

The Impact Of Spirituality And Trauma On Appraisals Of Psychotic-Like Experiences, Kathleen Isaac

Dissertations, Theses, and Capstone Projects

Background: A substantial portion of the general population (2.5% to 31.4% internationally) reports psychotic-like experiences, which are paranormal, psychic or bizarre perceptual experiences such as voice hearing, or holding strong beliefs (i.e. superstitions) that are neither experienced as pathological nor indicative of a psychotic disorder. Cognitive models of psychosis suggest that the cognitive appraisal (i.e. personal interpretation) of the experience may help distinguish non-clinical psychotic-like experiences from clinical psychotic symptoms. This dissertation attempted to add to cognitive models by assessing whether cultural and personal factors such as spirituality and trauma inform the appraisals of anomalous experiences. This study used a …

Does Genotype Correlate With Phenotype? Evaluating Ruffed Lemur (Varecia Spp.) Color Vision Using Subject Mediated Automatic Remote Testing Apparatus (Smarta), Raymond Vagell

Theses and Dissertations

Ruffed lemur (Varecia spp.) color vision research was conducted using a multidisciplinary approach: psychophysics, genetic analysis, technology, and animal training. The behavioral manifestation of Varecia spp. trichromacy was shown using a touchscreen apparatus (SMARTA). Trichromats performed better than dichromats when discriminating red from green (G₂ = 78.10, p < 0.001).

Physiological And Subjective Aspects Of Positive Mood In Relation To Executive Functioning: The Potential Moderating Role Of Personality, Luz Helena Ospina

Dissertations, Theses, and Capstone Projects

Positive affect has been demonstrated to improve aspects of cognition. However, recent studies reveal that positive affect may hinder the same cognitive processes, such as executive functioning, memory and creativity. These discrepant findings may be due to differing levels of physiological arousal, a component of the circumplex model of affect, which has been largely ignored in affective research. For example, one recent study suggests that positive valence coupled with varying levels of physiological arousal (i.e., low, moderate, and high) may differentially affect performance on tasks of verbal fluency and memory. Furthermore, one other explanation for these inconsistent findings may relate …

Age-Related Aspects Of Mirror-Use By Bottlenose Dolphins (Tursiops Truncatus), Rachel A. Morrison

Dissertations, Theses, and Capstone Projects

Bottlenose dolphins are neuroanatomically different and evolutionarily divergent from primates yet they exhibit mirror self-recognition (MSR), a rare cognitive ability in non-human animals. This research investigated the developmental and age-related aspects of MSR in this species. During a longitudinal study, a social group of bottlenose dolphins at the National Aquarium, Baltimore, MD were exposed to a mirror and their behavioral responses were recorded to: 1) further confirm the presence of MSR in this species, 2) determine the age of emergence of MSR and 3) draw comparisons with data documenting the emergence of this ability in humans and great ape species. …

Cisgenderism In Gender Attributions: The Ways In Which Social, Cognitive, And Individual Factors Predict Misgendering, Erica Jayne Friedman

Dissertations, Theses, and Capstone Projects

The current program of research investigated the ways in which social representations of gender, cognitive processes, and individual factors can be integrated to predict "misgendering," an example of cisgenderism in which people are categorized as a gender with which they do not identify. I proposed an (In)consistency Processing Model of Gender Attribution in which perceivers make a gender attribution by interpreting the stereotype-(in)consistencies of a target's gender characteristics through either a biology- or identity-based schema. Five studies were conducted to test different aspects of this model, the first of which was a secondary data analysis on a sample of students …

The Social Construction Of Authorship: An Investigation Of Subjectivity And Rhetorical Authority In The College Writing Classroom, Johannah Rodgers

Dissertations, Theses, and Capstone Projects

Although we use the term author on a daily basis to refer to certain individuals, bodies of work, and systems of ideas, as Michel Foucault and other critics have pointed out, attempting to answer the question “What is an Author?” is by no means a simple proposition. And, starting from the position that there is no single, or definitive answer to this complex question, this dissertation seeks to contribute to the ongoing discussion of the genealogy of authorship by investigating the ways in which conceptions of the author have informed models of the writing subject in the field of rhetoric …