Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Social and Behavioral Sciences
Meth Causes Expression Of 8-Ohg In The Addiction Pathway And Leads To Increased S-Glutathionylation Of The Vesicular Monoamine Transportor Via The Sigma Receptor, Taylor Hyde, Scott Steffensen
Meth Causes Expression Of 8-Ohg In The Addiction Pathway And Leads To Increased S-Glutathionylation Of The Vesicular Monoamine Transportor Via The Sigma Receptor, Taylor Hyde, Scott Steffensen
Journal of Undergraduate Research
Methamphetamine (METH) is a highly addictive drug of abuse and which results in serious financial, societal, and individual consequences in the United States. In 2005, METH abuse costs the country billions dollars each year. Societal and individual costs as a result of METH use are also high. Knowing how METH acts in the brain is a significant step in developing a pharmocotherapeutic treatment for METH addiction.
Role Of Sigma Receptors In Low-Dose Methamphetamine Modulation Of Dopamine Release In The Nucleus Accumbens, Gilbert Marchant, Scott Steffensen
Role Of Sigma Receptors In Low-Dose Methamphetamine Modulation Of Dopamine Release In The Nucleus Accumbens, Gilbert Marchant, Scott Steffensen
Journal of Undergraduate Research
Methamphetamine (METH) is an addictive drug of abuse and METH use is a growing problem in the United States. The current dogma states that psychostimulants such as METH attack the mesocorticolimbic dopamine (DA) system, leading to abnormally high DA release when drugs of abuse are taken (Volkow et al., 2004). A key target area of the mesocorticolimbic system is the nucleus accumbens (NAc). Specifically, DA release in the NAc has been associated with reward and motivation (Oleson et al. 2012).