Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
Psychology Faculty Scholarship
Vagal afferent innervation; cck-induced reduction; diet-induced obesity;food-intake; vagus nerve; spinal-cord; subdiaphragmatic vagotomy; nodose ganglionectomy; bariatric surgery; non-angiotensin
Articles 1 - 1 of 1
Full-Text Articles in Social and Behavioral Sciences
Sleeve Gastrectomy And Roux-En-Y Gastric Bypass Alter The Gut-Brain Communication, Lindsey Ballsmider, Alexandra Vaughn, Michelle David, Andras Hajnal, Patricia Di Lorenzo, Krzysztof Czaja
Sleeve Gastrectomy And Roux-En-Y Gastric Bypass Alter The Gut-Brain Communication, Lindsey Ballsmider, Alexandra Vaughn, Michelle David, Andras Hajnal, Patricia Di Lorenzo, Krzysztof Czaja
Psychology Faculty Scholarship
This study investigated the anatomical integrity of vagal innervation of the gastrointestinal tract following vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) operations. The retrograde tracer fast blue (FB) was injected into the stomach to label vagal neurons originating from nodose ganglion (NG) and dorsal motor nucleus of the vagus (DMV). Microglia activation was determined by quantifying changes in the fluorescent staining of hindbrain sections against an ionizing calcium adapter binding molecule 1 (Iba1). Reorganization of vagal afferents in the hindbrain was studied by fluorescent staining against isolectin 4 (IB4). The density of Iba1-and IB4-immunoreactivity was analyzed using Nikon …