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Full-Text Articles in Social and Behavioral Sciences

A Behavioural Comparison Of Acute And Chronic Δ9-Tetrahydrocannabinol And Cannabidiol In C57bl/6jarc Mice, Ian Mcgregor, Xu-Feng Huang, Tim Karl, Jonathon Arnold, Rose Chesworth, Leonora E. Long Sep 2012

A Behavioural Comparison Of Acute And Chronic Δ9-Tetrahydrocannabinol And Cannabidiol In C57bl/6jarc Mice, Ian Mcgregor, Xu-Feng Huang, Tim Karl, Jonathon Arnold, Rose Chesworth, Leonora E. Long

Xu-Feng Huang

Cannabis contains over 70 unique compounds and its abuse is linked to an increased risk of developing schizophrenia. The behavioural profiles of the psychotropic cannabis constituent Δ9-tetrahydrocannabinol (Δ9-THC) and the non-psychotomimetic constituent cannabidiol (CBD) were investigated with a battery of behavioural tests relevant to anxiety and positive, negative and cognitive symptoms of schizophrenia. Male adult C57BL/6JArc mice were given 21 daily intraperitoneal injections of vehicle, Δ9-THC (0.3, 1, 3 or 10 mg/kg) or CBD (1, 5, 10 or 50 mg/kg). Δ9-THC produced the classic cannabinoid CB1 receptor-mediated tetrad of hypolocomotion, analgesia, catalepsy and hypothermia while CBD had modest hyperthermic effects. …


Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi Sep 2012

Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi

Xu-Feng Huang

A growing number of studies have identified chronic sleep restriction as a potential risk factor for obesity. This could have important implications for how obesity is prevented and managed, but current understanding of the processes linking chronic sleep restriction to obesity is incomplete. In this paper, we examined some of the pathways that could underlie the relationship between chronic sleep restriction and obesity. This involved exploring some of the potential environmental, health, behavioral, and sociodemographic determinants of chronic sleep restriction, which require further investigation in this context. Three pathways that could potentially link chronic sleep restriction to obesity were then …


Collaborative Recovery: An Integrative Model For Working With Individuals Who Experience Chronic And Recurring Mental Illness, Lindsay G. Oades, Frank P. Deane, Trevor P. Crowe, Gordon Lambert, David Kavanagh, Christopher Lloyd Aug 2012

Collaborative Recovery: An Integrative Model For Working With Individuals Who Experience Chronic And Recurring Mental Illness, Lindsay G. Oades, Frank P. Deane, Trevor P. Crowe, Gordon Lambert, David Kavanagh, Christopher Lloyd

Frank Deane

Objectives: Recovery is an emerging movement in mental health. Evidence for recovery-based approaches is not well developed and approaches to implement recovery-oriented services are not well articulated. The collaborative recovery model (CRM) is presented as a model that assists clinicians to use evidencebased skills with consumers, in a manner consistent with the recovery movement. A current 5 year multisite Australian study to evaluate the effectiveness of CRM is briefly described. Conclusion: The collaborative recovery model puts into practice several aspects of policy regarding recovery-oriented services, using evidence-based practices to assist individuals who have chronic or recurring mental disorders (CRMD). It …


Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi Jun 2012

Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi

Don C. Iverson

A growing number of studies have identified chronic sleep restriction as a potential risk factor for obesity. This could have important implications for how obesity is prevented and managed, but current understanding of the processes linking chronic sleep restriction to obesity is incomplete. In this paper, we examined some of the pathways that could underlie the relationship between chronic sleep restriction and obesity. This involved exploring some of the potential environmental, health, behavioral, and sociodemographic determinants of chronic sleep restriction, which require further investigation in this context. Three pathways that could potentially link chronic sleep restriction to obesity were then …


Collaborative Recovery: An Integrative Model For Working With Individuals Who Experience Chronic And Recurring Mental Illness, Lindsay G. Oades, Frank P. Deane, Trevor P. Crowe, Gordon Lambert, David Kavanagh, Christopher Lloyd Jan 2012

Collaborative Recovery: An Integrative Model For Working With Individuals Who Experience Chronic And Recurring Mental Illness, Lindsay G. Oades, Frank P. Deane, Trevor P. Crowe, Gordon Lambert, David Kavanagh, Christopher Lloyd

Trevor Crowe

Objectives: Recovery is an emerging movement in mental health. Evidence for recovery-based approaches is not well developed and approaches to implement recovery-oriented services are not well articulated. The collaborative recovery model (CRM) is presented as a model that assists clinicians to use evidencebased skills with consumers, in a manner consistent with the recovery movement. A current 5 year multisite Australian study to evaluate the effectiveness of CRM is briefly described. Conclusion: The collaborative recovery model puts into practice several aspects of policy regarding recovery-oriented services, using evidence-based practices to assist individuals who have chronic or recurring mental disorders (CRMD). It …


Gender Differences In Cognitive Function Of Patients With Chronic Schizophrenia, Mei Han, Xu-Feng Huang, Da Chun Chen, Mei Hong Xiu, Li Hui, Haibo Liu, Thomas R. Kosten, Xiang Yang Zhang Jan 2012

Gender Differences In Cognitive Function Of Patients With Chronic Schizophrenia, Mei Han, Xu-Feng Huang, Da Chun Chen, Mei Hong Xiu, Li Hui, Haibo Liu, Thomas R. Kosten, Xiang Yang Zhang

Faculty of Science, Medicine and Health - Papers: part A

Schizophrenic patients have cognitive impairments, but gender differences in these cognitive deficits have had limited study. This study assessed cognitive functioning in 471 subjects including 122 male and 78 female schizophrenic patients and 141 male and 130 female healthy controls. We found that immediate memory, language, delayed memory and total RBANS scores were significantly decreased in schizophrenia compared with healthy controls for both genders. Male patients had significant lower immediate memory, delayed memory and total RBANS scores than female patients, and healthy controls showed a similar gender difference. The RBANS showed modest correlations with PANSS scores, duration of illness and …


Understanding And Benchmarking Health Service Achievement Of Policy Goals For Chronic Disease, Erica Bell, Bastian Seidel Jan 2012

Understanding And Benchmarking Health Service Achievement Of Policy Goals For Chronic Disease, Erica Bell, Bastian Seidel

Faculty of Science, Medicine and Health - Papers: part A

Background Key challenges in benchmarking health service achievement of policy goals in areas such as chronic disease are: 1) developing indicators and understanding how policy goals might work as indicators of service performance; 2) developing methods for economically collecting and reporting stakeholder perceptions; 3) combining and sharing data about the performance of organizations; 4) interpreting outcome measures; 5) obtaining actionable benchmarking information. This study aimed to explore how a new Boolean-based small-N method from the social sciences—Qualitative Comparative Analysis or QCA—could contribute to meeting these internationally shared challenges. Methods A ‘multi-value QCA’ (MVQCA) analysis was conducted of data from 24 …


Participant Experiences From Chronic Administration Of A Multivitamin Versus Placebo On Subjective Health And Wellbeing: A Double-Blind Qualitative Analysis Of A Randomised Controlled Trial, Jerome Sarris, Katherine H M Cox, David A. Camfield, Andrew Scholey, Con Stough, Erin Fogg, Marni Kras, David J. White, Avni Sali, Andrew Pipingas Jan 2012

Participant Experiences From Chronic Administration Of A Multivitamin Versus Placebo On Subjective Health And Wellbeing: A Double-Blind Qualitative Analysis Of A Randomised Controlled Trial, Jerome Sarris, Katherine H M Cox, David A. Camfield, Andrew Scholey, Con Stough, Erin Fogg, Marni Kras, David J. White, Avni Sali, Andrew Pipingas

Faculty of Social Sciences - Papers (Archive)

Background While many randomised controlled trials have been conducted on multivitamins, to our knowledge no qualitative research exploring the subjective experience of taking a multivitamin during a clinical trial has been reported. Methods Semi-structured and open-ended written questions were incorporated into a 16-week double-blind, randomised, placebo-controlled, parallel groups trial of once-daily multivitamin administration. At the final study visit (week 16), three open-ended questions were posed to elucidate any positive, negative or unusual experiences from taking either the multivitamin or matched placebo. Qualitative thematic analysis was undertaken by researchers who were blind as to treatment condition of participants, and triangulation (independent …


Functional Connectivity In Brain Networks Underlying Cognitive Control In Chronic Cannabis Users, Ian H. Harding, Nadia Solowij, Ben J. Harrison, Michael Takagi, Valentina Lorenzetti, Dan I. Lubman, Marc L. Seal, Christos Pantelis, Murat Yucel Jan 2012

Functional Connectivity In Brain Networks Underlying Cognitive Control In Chronic Cannabis Users, Ian H. Harding, Nadia Solowij, Ben J. Harrison, Michael Takagi, Valentina Lorenzetti, Dan I. Lubman, Marc L. Seal, Christos Pantelis, Murat Yucel

Faculty of Health and Behavioural Sciences - Papers (Archive)

The long-term effect of regular cannabis use on brain function underlying cognitive control remains equivocal. Cognitive control abilities are thought to have a major role in everyday functioning, and their dysfunction has been implicated in the maintenance of maladaptive drug-taking patterns. In this study, the Multi-Source Interference Task was employed alongside functional magnetic resonance imaging and psychophysiological interaction methods to investigate functional interactions between brain regions underlying cognitive control. Current cannabis users with a history of greater than 10 years of daily or near-daily cannabis smoking (n=21) were compared with age, gender, and IQ-matched non-using controls (n=21). No differences in …


Care Of Patients With A Diagnosis Of Chronic Obstructive Pulmonary Disease: A Cluster Randomised Controlled Trial, Nicholas Zwar, Oshana Hermiz, Elizabeth J. Comino, Sandy Middleton, Sanjyot Vagholkar, Wei Xuan, Stephen F. Wilson, Guy B. Marks Jan 2012

Care Of Patients With A Diagnosis Of Chronic Obstructive Pulmonary Disease: A Cluster Randomised Controlled Trial, Nicholas Zwar, Oshana Hermiz, Elizabeth J. Comino, Sandy Middleton, Sanjyot Vagholkar, Wei Xuan, Stephen F. Wilson, Guy B. Marks

Faculty of Science, Medicine and Health - Papers: part A

Objective: To evaluate a partnership model of care for patients with a diagnosis of chronic obstructive pulmonary disease (COPD). Design, setting and participants: Cluster randomised controlled trial with blinded outcome assessment of 44 general practices in south-western Sydney comprising 451 people with a diagnosis of COPD, conducted between 2006 and 2009. Intervention: Participants from intervention group practices were visited at their home by a registered nurse with specific training in COPD care who worked with the general practitioner, the patient and other health professionals to develop and implement an individualised care plan based on best-practice guidelines. Participants from control group …