Social and Behavioral Sciences Commons^™

"What Is A Wave But 1000 Drops Working Together?": The Role Of Public Libraries In Addressing Lgbtqia+ Health Information Disparities, Vanessa Lynn Kitzie, A. Nick Vera, Valerie Lookingbill, Travis L. Wagner

Faculty Publications

Purpose. This paper presents results from a participatory action research study with 46 LGBTQIA+ community leaders and 60 library workers who participated in four community forums at public libraries across the US. The forums identified barriers to LGBTQIA+ communities addressing their health questions and concerns and explored strategies for public libraries to tackle them.

Design/methodology/approach. Forums followed the World Café format to facilitate collaborative knowledge development and promote participant-led change. Data sources included collaborative notes taken by participants and observational researcher notes. Data analysis consisted of emic/etic qualitative coding.

Findings. Results revealed that barriers experienced by LGBTQIA+ communities are structurally …

Ancient Pathogens Provide A Window Into Health And Well-Being, Cecil M. Lewis Jr., Mercy Y. Akinyi, Sharon Dewitte, Anne C. Stone

Faculty Publications

This perspective draws on the record of ancient pathogen genomes and microbiomes illuminating patterns of infectious disease over the course of the Holocene in order to address the following question. How did major changes in living circumstances involving the transition to and intensification of farming alter pathogens and their distributions? Answers to this question via ancient DNA research provide a rapidly expanding picture of pathogen evolution and in concert with archaeological and historical data, give a temporal and behavioral context for heath in the past that is relevant for challenges facing the world today, including the rise of novel pathogens.

Co-Creation Of A Training For Community Health Workers To Enhance Skills In Serving Lgbtqia+ Communities, Vanessa Kitzie, Julie Smithwick, Carmen Blanco, M. Greg Green, Sarah Covington-Kolb

Faculty Publications

This paper describes creating and implementing a 30-h LGBTQIA+ specialty training for community health workers (CHWs). The training was co-developed by CHW training facilitators (themselves CHWs), researchers with expertise in LGBTQIA+ populations and health information, and a cohort of 11 LGBTQIA+ CHWs who theater tested and piloted the course. The research and training team collected cohort feedback through focus groups and an evaluative survey. Findings stress the importance of a curriculum designed to elicit lived experiences and informed by a pedagogical framework centered on achieving LGBTQIA+ visibilities. This training is a vital tool for CHWs to foster cultural humility for …

Queer Mediated Practices As A Method To Center And Sustain Critical Health And Media Literacies, Alexander N. Vera, Vanessa Kitzie, Travis L. Wagner

Faculty Publications

Queer communities experience challenges when accessing accurate and comprehensive health information. These challenges span across media and information environments and threaten queer health promotion. This paper explored how 11 queer community health workers (CHWs) in a Southeastern US state respond to, subvert, and resist these challenges when creating digital health information resources for their queer communities. This longitudinal action research occurred over two years and included multiple qualitative data types. We analyzed these data using qualitative coding, following deductive and inductive strategies. Findings demonstrate how queer CHWs: 1) identified risks and barriers to health promotion their communities experienced; 2) created …

“What Is A Wave But 1000 Drops Working Together?”: The Role Of Public Libraries In Addressing Lgbtqia+ Health Information Disparities, Vanessa Kitzie, Alexander N. Vera, Valerie Lookingbill, Travis L. Wagner

Faculty Publications

This paper presents results from a participatory action research study with 46 LGBTQIA+ community leaders and 60 library workers who participated in four community forums at public libraries across the US. The forums identified barriers to LGBTQIA+ communities addressing their health questions and concerns and explored strategies for public libraries to tackle them. Forums followed the World Café format to facilitate collaborative knowledge development and promote participant-led change. Data sources included collaborative notes taken by participants and observational researcher notes. Results revealed that barriers experienced by LGBTQIA+ communities are structurally and socially entrenched and require systematic changes. Public libraries must …

White Matter Hyperintensity Load Is Associated With Premature Brain Aging, Natalie Busby, Sarah Newman-Norlund, Sara Sayers, Roger Newman-Norlund, Sarah Wilson, Samaneh Nemati, Chris Rorden, Janina Wilmskoetter, Nicholas Riccardi, Rebecca Roth, Julius Fridriksson, Leonardo Bonilha

Faculty Publications

Background: Brain age is an MRI-derived estimate of brain tissue loss that has a similar pattern to aging-related atrophy. White matter hyperintensities (WMHs) are neuroimaging markers of small vessel disease and may represent subtle signs of brain compromise. We tested the hypothesis that WMHs are independently associated with premature brain age in an original aging cohort.

Methods: Brain age was calculated using machine-learning on whole-brain tissue estimates from T1-weighted images using the BrainAgeR analysis pipeline in 166 healthy adult participants. WMHs were manually delineated on FLAIR images. WMH load was defined as the cumulative volume of WMHs. A positive difference …

“Nothing To Do But Be Borne And Steered”: Unpacking Feminist Scripts In Elana Arnold’S Damsel, Jenna Spiering, Nicole Ann Amato

Faculty Publications

Feminism in novels marketed for young adults often reflects the values of a popular feminism that relies on individual and personal means of empowerment, rather than critiquing or seeking to dismantle systems of domination. In this paper, we illumminate frameworks and methods for engaging students in careful readings and evaluations of texts marketed as feminist, through an analysis of Elana Arnold’s feminist fairy tale, Damsel (2018). Drawing on theoretical frameworks of popular feminism, feral feminism, and theories of becoming, the authors use Critical Content Anlaysis to explore several tenets in contemporary feminist thought in order to analyze Arnold’s text and …

The Role Of A Green Bank In South Carolina: A Market & Feasibility Assessment, Jory Fleming, Claire Windsor

Faculty Publications

A market and feasibility report that explores the role of a green bank in South Carolina. This report is the culmination of a multi-year process that included a comprehensive market assessment and interviews with over 60 organizations across South Carolina. It demonstrates that a green bank could play a vital role in South Carolina by creating a dedicated institution working to accelerate the flow of capital to projects that seek to reduce carbon pollution and increase resilience to climate impacts.

Association Of Caregiver Attitudes With Adolescent Hpv Vaccination In 13 Southern Us States, Lavanya Vasudevan, Jan Ostermann, Yunfei Wang, Sayward Harrison, Valerie Yelverton, Laura J. Fish, Charnetta Williams, Emmanuel B. Walter

Faculty Publications

Background and objectives: HPV vaccination coverage is lower than that of other adolescent vaccines in the southern US. This study sought to characterize caregiver attitudes associated with adolescent HPV vaccination in the southern US and to inform interventions to promote HPV vaccination. Methods: From December 2019 – January 2020, caregivers of adolescents (ages 9–17 years) living in thir- teen southern US states were recruited from a nationally-representative online survey panel. Caregivers (N = 1,105) completed a cross-sectional survey that assessed general adolescent vaccine attitudes as well as those associated with the HPV vaccine and HPV vaccination decision-making. The primary study …

Bias In Measurement Of Autism Symptoms By Spoken Language Level And Non-Verbal Mental Age In Minimally Verbal Children With Neurodevelopmental Disorders, Shuting Zheng, Aaron Kaat, Cristan Farmer, Audrey Thurm, Catherine A. Burrows, Stephen Kanne, Stelios Georgiades, Amy Esler, Catherine Lord, Nicole Takashashi, Kerri P. Nowell, Elizabeth A. Will Ph.D., Jane E. Roberts, Somer L. Bishop

Faculty Publications

Increasing numbers of children with known genetic conditions and/or intellectual disability are referred for evaluation of autism spectrum disorder (ASD), highlighting the need to refine autism symptom measures to facilitate differential diagnoses in children with cognitive and language impairments. Previous studies have reported decreased specificity of ASD screening and diagnostic measures in children with intellectual disability. However, little is known about how cognitive and language abilities impact the measurement of specific ASD symptoms in this group. We aggregated a large sample of young children (N = 1196; aged 31-119 months) to examine measurement invariance of ASD symptoms among minimally verbal …

Sexual Stature Difference Fluctuations In Pre- And Post-Black Death London As An Indicator Of Living Standards, Emily J. Brennan, Sharon Dewitte

Faculty Publications

Objectives: The degree of sexual stature difference (SSD), the ratio of male to female height, is argued to be an indicator of living standards based on evidence that physical growth for males is more sensitive to environmental fluctuations. In a resource-poor environment, the degree of SSD is expected to be relatively low. The aim of this study is to comparatively assess SSD in medieval London in the context of repeated famine events and other environmental stressors before the Black Death (BD) and the improved living conditions that characterized the post-Black Death period.

Methods: To test the hypothesis that a poor …

Parochial Altruism And Political Ideology, Marilynn B. Brewer, Nancy R. Buchan, Orgul D. Ozturk, Gianluca Grimalda

Faculty Publications

Parochial altruism refers to the propensity to direct prosocial behavior toward members of one's own ingroup to a greater extent than toward those outside one's group. Both theory and empirical research suggest that parochialism may be linked to political ideology, with conservatives more likely than liberals to exhibit ingroup bias in altruistic behavior. The present study, conducted in the United States and Italy, tested this relationship in the context of the COVID-19 pandemic, assessing willingness to contribute money to charities at different levels of inclusiveness—local versus national versus international. Results indicated that conservatives contributed less money overall and were more …

Future Orientation Among Children Affected By Parental Hiv In China: An Exploratory Analysis Of Complex Interactions, Heather L. Mcdaniel, Sayward Harrison, Amanda Fairchild, Xiaoming Li

Faculty Publications

We utilized an exploratory analytic approach to examine predictors of children's future beliefs, an internal asset associated with resilience among children affected by HIV, with emphasis on complex interactions among multisystem factors. Children (N = 1221) affected by parental HIV in China reported on psychosocial functioning, as well as internal, familial, and community resilience assets. Exploratory data analysis was conducted using a binary segmentation program. Six binary splits on predictors accounted for 22.78% of the variance in future expectation, suggesting interactions between children's perceived control of their future, loneliness, caregiver trust, and social support. Four binary splits accounted for …

Intraneuronal Β-Amyloid Accumulation: Aging Hiv-1 Human And Hiv-1 Transgenic Rat Brain, Hailong Li, Kristen A. Mclaurin, Charles F. Mactutus, Benjamin Linkins, Wenfei Huang, Sulie L. Chang, Rosemarie M. Booze

Faculty Publications

The prevalence of HIV-1 associated neurocognitive disorders (HAND) is significantly greater in older, relative to younger, HIV-1 seropositive individuals; the neural pathogenesis of HAND in older HIV-1 seropositive individuals, however, remains elusive. To address this knowledge gap, abnormal protein aggregates (i.e., β-amyloid) were investigated in the brains of aging (>12 months of age) HIV-1 transgenic (Tg) rats. In aging HIV-1 Tg rats, double immunohistochemistry staining revealed abnormal intraneuronal β-amyloid accumulation in the prefrontal cortex (PFC) and hippocampus, relative to F344/N control rats. Notably, in HIV-1 Tg animals, increased β-amyloid accumulation occurred in the absence of any genotypic changes in …

Unrestricted Factor Analysis: A Powerful Alternative To Confirmatory Factor Analysis, Jan-Benedict E.M. Steenkamp, Alberto Maydeu-Olivares

Faculty Publications

The gold standard for modeling multiple indicator measurement data is confirmatory factor analysis (CFA), which has many statistical advantages over traditional exploratory factor analysis (EFA). In most CFA applications, items are assumed to be pure indicators of the construct they intend to measure. However, despite our best efforts, this is often not the case. Cross-loadings incorrectly set to zero can only be expressed through the correlations between the factors, leading to biased factor correlations and to biased structural (regression) parameter estimates. This article introduces a third approach, which has emerged in the psychometric literature, viz., unrestricted factor analysis (UFA). UFA …

Predictors Of Therapy Response In Chronic Aphasia: Building A Foundation For Personalized Aphasia Therapy, Sigfus Kristinsson, Dirk B. Den Ouden, Chris Rorden, Roger Newman-Norlund

Faculty Publications

Chronic aphasia, a devastating impairment of language, affects up to a third of stroke survivors. Speech and language therapy has consistently been shown to improve language function in prior clinical trials, but few clinicially applicable predictors of individual therapy response have been identified to date. Consequently, clinicians struggle substantially with prognostication in the clinical management of aphasia. A rising prevalence of aphasia, in particular in younger populations, has emphasized the increasing demand for a personalized approach to aphasia therapy, that is, therapy aimed at maximizing language recovery of each individual with reference to evidence-based clinical recommendations. In this narrative review, …

Key Stakeholder Perspectives On Challenges And Opportunities For Rural Hpv Vaccination In North And South Carolina, Laura J. Fish, Sayward Harrison, Jodi-Ann Mcdonald, Valerie Yelverton, Charnetta Williams, Emmanuel B. Walter, Lavanya Vasudevan

Faculty Publications

The objective of this study was to identify factors at the individual, provider, and systems levels that serve as challenges or opportunities for increasing adolescent vaccination—including Human Papillomavirus (HPV) vaccination—in rural communities in the southern United States (US). As part of a broader study to increase HPV vaccine uptake in the southern US, we conducted in-depth interviews with vaccination stakeholders representing public health and education agencies in North Carolina (NC) and South Carolina (SC). Fourteen key stakeholders were recruited using purposive sampling to obtain insights into challenges and solutions to rural-urban disparities in HPV vaccination coverage. Stakeholders were also queried …

Neural Correlates Of Impaired Vocal Feedback Control In Post-Stroke Aphasia, Roozbeh Behroozmand, Leonardo Bonilha, Chris Rorden, Gregory Hickok, Julius Fridriksson

Faculty Publications

We used left-hemisphere stroke as a model to examine how damage to sensorimotor brain networks impairs vocal auditory feedback processing and control. Individuals with post-stroke aphasia and matched neurotypical control subjects vocalized speech vowel sounds and listened to the playback of their self-produced vocalizations under normal (NAF) and pitch-shifted altered auditory feedback (AAF) while their brain activity was recorded using electroencephalography (EEG) signals. Event-related potentials (ERPs) were utilized as a neural index to probe the effect of vocal production on auditory feedback processing with high temporal resolution, while lesion data in the stroke group was used to determine how brain …

Canonical Sentence Processing And The Inferior Frontal Cortex: Is There A Connection?, Nicholas Riccardi, Chris Rorden, Julius Fridriksson, Rutvik H. Desai

Faculty Publications

The role of left inferior frontal cortex (LIFC) in canonical sentence comprehension is controversial. Many studies have found involvement of LIFC in sentence production or complex sentence comprehension, but negative or mixed results are often found in comprehension of simple or canonical sentences. We used voxel-, region-, and connectivity-based lesion symptom mapping (VLSM, RLSM, CLSM) in left-hemisphere chronic stroke survivors to investigate canonical sentence comprehension while controlling for lexical-semantic, executive, and phonological processes. We investigated how damage and disrupted white matter connectivity of LIFC and two other language-related regions, the left anterior temporal lobe (LATL) and posterior temporal-inferior parietal area …

A Resilience-Based Intervention To Mitigate The Effect Of Hiv-Related Stigma: Protocol For A Stepped Wedge Cluster Randomized Trial, Xiaoming Li, Shan Qiao, Xueying Yang, Sayward Harrison, Cheuk Chi Tam, Zhiyong Shen, Yuejiao Zhou

Faculty Publications

Background: Despite decades of global efforts to tackle HIV-related stigma, previous interventions designed to reduce stigma have had limited effects that were typically in the small- to-moderate range. The knowledge gaps and challenges for combating HIV-related stigma are rooted both in the complexity of the stigma and in the limitations of current conceptualizations of stigma reduction efforts. Recent research has shown the promise of resilience-based approaches that focus on the development of strengths, competencies, resources, and capacities of people living with HIV (PLWH) and their key supporting systems (e.g., family members and healthcare providers) to prevent, reduce, and mitigate the …

Mindfulness, Psychological Distress, And Somatic Symptoms Among Women Engaged In Sex Work In China, Cheuk Chi Tam, Yuejiao Zhou, Shan Qiao, Xiaoming Li Ph.D., Zhiyong Shen

Faculty Publications

Women engaged in sex work (WSW) in China encounter numerous disadvantages (e.g., exposure to violence) and have substantial risk for psychological distress and somatic symptoms. Intervention literature has attended to mindfulness, which is a protective factor for psychological outcomes, and its influences can further improve physical health. However, mindfulness has not been well studied in WSW. We aimed to examine the association among mindfulness, psychological distress, and somatic symptoms among Chinese WSW. Data were collected from 410 WSW in Guangxi, China, using an anonymous, self-administered survey evaluating demographics, mindfulness, psychological distress (i.e., depression, loneliness, and perceived stress), and somatic symptoms …

Including Latinx Communities In Academic Libraries: A Theoretical Approach To Information Access, Andrew A. Wakelee, Kim M. Thompson

Faculty Publications

While more Latinx students continue to enroll in higher education, physical, intellectual, and socio-cultural barriers to information may continue to impede their success and inclusion. A tripartite theoretical model that examines physical, intellectual, and socio-cultural information access provides insights for academic libraries to better meet Latinx students’ information needs and include them in campus life. This paper gives an overview of the theoretical framework along with practical steps libraries can take to improve information equity.

Functional Differentiation In The Language Network Revealed By Lesion-Symptom Mapping, William Matchin, Alexandra Basilaskos, Dirk-Bart Den-Ouden, Brielle C. Stark, Gregory Hickok, Julius Fridiksson

Faculty Publications

Theories of language organization in the brain commonly posit that different regions underlie distinct linguistic mechanisms. However, such theories have been criticized on the grounds that many neuroimaging studies of language processing find similar effects across regions. Moreover, condition by region interaction effects, which provide the strongest evidence of functional differentiation between regions, have rarely been offered in support of these theories. Here we address this by using lesion-symptom mapping in three large, partially-overlapping groups of aphasia patients with left hemisphere brain damage due to stroke ( N = 121, N = 92, N = 218). We identified multiple measure …

Association Of Neovascular Age-Related Macular Degeneration With Migraine, Tung-Mei Kuang, Sudha Xirasagar, Yi-Wei Kao, Jau-Der Ho, Herng-Ching Lin

Faculty Publications

Patients with early onset vascular pathology have been reported to manifest neovascular age-related macular degeneration (AMD). While the blood vessels involved in pathogenesis of migraine remains controversial, it is generally accepted that a major contributor is blood vessel pathology. This study aimed to examine the association between migraine and AMD using a nationwide population-based dataset. Retrospective claims data were collected from the Taiwan National Health Insurance Research Database. We identified 20,333 patients diagnosed with neovascular AMD (cases), and we selected 81,332 propensity score-matched controls from the remaining beneficiaries in Taiwan's National Health Insurance system. We used Chi-square tests to explore …

Deep Learning Of High-Resolution Aerial Imagery For Coastal Marsh Change Detection: A Comparative Study, Grayson R. Morgan, Cuizhen Wang, Zhenlong Li, Steven R. Schill, Daniel R. Morgan

Faculty Publications

Deep learning techniques are increasingly being recognized as effective image classifiers. Aside from their successful performance in past studies, the accuracies have varied in complex environments, in comparison with the popularly of applied machine learning classifiers. This study seeks to explore the feasibility of using a U-Net deep learning architecture to classify bi-temporal, high-resolution, county-scale aerial images to determine the spatial extent and changes of land cover classes that directly or indirectly impact tidal marsh. The image set used in the analysis is a collection of a 1-m resolution collection of National Agriculture Imagery Program (NAIP) tiles from 2009 and …

Unmanned Aerial Remote Sensing Of Coastal Vegetation: A Review, Grayson R. Morgan, Michael E. Hodgson, Cuizhen Wang, Steven R. Schill

Faculty Publications

Coastal wetlands contribute greatly to our coasts economically and ecologically. The utility of coastal wetland vegetation, along with the multitude of dynamic forces they encounter, suggests the need of regular monitoring for sustainable management. While traditional in situ survey methods and remote sensing from space and manned platforms have provided means to monitor and study the coastal zone thus far, the recent developments of small unmanned aerial systems (sUAS) fill a small void between traditional in situ survey methods and the high spatial resolution of manned aircraft imagery. As an on-demand personal remote sensing device, an sUAS can be deployed …

Family History Of Fxtas Is Associated With Age-Related Cognitive-Linguistic Decline Among Mothers With The Fmr1 Premutation, Jessica Klusek, Amanda Fairchild, Carly Moser, Marsha R. Mailick, Angela John Thurman, Leonard Abbeduto

Faculty Publications

BACKGROUND: Women who carry a premutation allele of the FMR1 gene are at increased vulnerability to an array of age-related symptoms and disorders, including age-related decline in select cognitive skills. However, the risk factors for age-related decline are poorly understood, including the potential role of family history and genetic factors. In other forms of pathological aging, early decline in syntactic complexity is observed and predicts the later onset of neurodegenerative disease. To shed light on the earliest signs of degeneration, the present study characterized longitudinal changes in the syntactic complexity of women with the FMR1 premutation across midlife, and associations …

Disruptions Of The Human Connectome Associated With Hemispatial Neglect, Sadhvi Saxena, Zafer Keser, Chris Rorden, Leonardo Bonilha, Julius Fridriksson Ph.D., Alexandra Walker, Argye Elizabeth Hillis

Faculty Publications

Background and Objectives

Hemispatial neglect is a heterogeneous and complex disorder that can be classified by frame of reference for “left” vs “right,” including viewer-centered neglect (VCN, affecting the contralesional side of the view), stimulus-centered neglect (SCN, affecting the contralesional side of the stimulus, irrespective of its location with respect to the viewer), or both. We investigated the effect of acute stroke lesions on the connectivity of neural networks that underlie VCN or SCN.

Methods

A total of 174 patients within 48 hours of acute right hemispheric infarct underwent a detailed hemispatial neglect assessment that included oral reading, scene copy, …

Protocol For Escitalopram And Language Intervention For Subacute Aphasia (Elisa): A Randomized, Double Blind, Placebo-Controlled Trial, Melissa D. Stockbridge, Julius Fridriksson, Souvik Sen, Leonardo Bonilha

Faculty Publications

In this forthcoming multicenter, prospective, randomized, double-blind placebo-controlled trial, we will investigate the augmentative effects of a selective serotonin reuptake inhibitor, escitalopram, on language therapy in individuals with post-stroke aphasia. We hypothesize that, when combined with language therapy, daily escitalopram will result in greater improvement than placebo in an untrained picture naming task (Philadelphia Naming Test short form) administered one week after the end of language therapy. We also will examine whether escitalopram's effect on language is independent of its effect on depression, varies with lesion location, or is associated with increased functional connectivity within the left hemisphere. Finally, we …

At-Sensor Radiometric Correction Of A Multispectral Camera (Rededge) For Suas Vegetation Mapping, Cuizhen Wang

Faculty Publications

Rapid advancement of drone technology enables small unmanned aircraft systems (sUAS) for quantitative applications in public and private sectors. The drone-mounted 5-band MicaSense RedEdge cameras, for example, have been popularly adopted in the agroindustry for assessment of crop healthiness. The camera extracts surface reflectance by referring to a pre-calibrated reflectance panel (CRP). This study tests the performance of a Matrace100/RedEdge-M camera in extracting surface reflectance orthoimages. Exploring multiple flights and field experiments, an at-sensor radiometric correction model was developed that integrated the default CRP and a Downwelling Light Sensor (DLS). Results at three vegetated sites reveal that the current CRP-only …