Social and Behavioral Sciences Commons^™

Each Sensory Nerve Arising From The Geniculate Ganglion Expresses A Unique Fingerprint Of Neurotrophin Receptor Genes, Albert I. Farbman, Nick Guagliardo, Suzanne I. Sollars, David L. Hill

Psychology Faculty Publications

Neurons in the geniculate ganglion, like those in other sensory ganglia, are dependent on neurotrophins for survival. Most geniculate ganglion neurons innervate taste buds in two regions of the tongue and two regions of the palate; the rest are cutaneous nerves to the skin of the ear. We investigated the expression of four neurotrophins, nerve growth factor (NGF), brain‐derived neurotrophic factor (BDNF), neurotrophin 3 (NT‐3), and NT‐4, and five neurotrophin receptors, trkA, trkB, trkC, p75, and truncated trkB (Trn‐B) in single sensory neurons of the adult rat geniculate ganglion associated with the five innervation fields. For fungiform papillae, a glass …