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Articles 1 - 4 of 4
Full-Text Articles in Social and Behavioral Sciences
Neuropeptide Y Mrna Expression Levels Following Chronic Olanzapine, Clozapine And Haloperidol Administration In Rats, Xu-Feng Huang, Katerina Zavitsanou, Chao Deng
Neuropeptide Y Mrna Expression Levels Following Chronic Olanzapine, Clozapine And Haloperidol Administration In Rats, Xu-Feng Huang, Katerina Zavitsanou, Chao Deng
Xu-Feng Huang
No abstract provided.
Perinatal Administration Of Pcp Alters Adult Behaviour In Female Sprague-Dawley Rats, Teresa Du Bois, Xu-Feng Huang, Chao Deng
Perinatal Administration Of Pcp Alters Adult Behaviour In Female Sprague-Dawley Rats, Teresa Du Bois, Xu-Feng Huang, Chao Deng
Xu-Feng Huang
Perinatal phencyclidine (PCP) treatment leads to neuronal damage and causes long-term behavioural alterations in rodents. This study examined the effects of perinatal PCP treatment on behaviour of adult rats in holeboard, elevated plus maze, social interaction and forced swim tests. PCP-treated rats displayed hyperactivity in the holeboard and forced swim tests. These persistent behavioural changes are relevant to the study of psychiatric disorders such as schizophrenia.
Rapid Cortico-Limbic Alterations In Ampa Receptor Densities After Administration Of Pcp: Implications For Schizophrenia., Van Nguyen, Kelly Newell, Xu-Feng Huang, Katerina Zavitsanou, P Ballantyne
Rapid Cortico-Limbic Alterations In Ampa Receptor Densities After Administration Of Pcp: Implications For Schizophrenia., Van Nguyen, Kelly Newell, Xu-Feng Huang, Katerina Zavitsanou, P Ballantyne
Xu-Feng Huang
Phencyclidine (PCP), a non-competitive NMDA/glutamate receptor antagonist, is a psychotomimetic drug that produces a syndrome in normal humans that resembles schizophrenia. The present study investigated the mechanisms of PCP actions by examining the density of glutamate and muscarinic receptors in the rat brain 4 h after a single injection of PCP. We used receptor autoradiography and [3H]MK801, [3H]AMPA, [3H]pirenzepine and [3H]AFDX384 to target glutamate NMDA, glutamate AMPA and muscarinic M1 and M2 receptors, respectively. The major outcome from the present study was an overall decrease in levels of the glutamate AMPA receptor density (F = 14.5, d.f. = 1, p …
Systematic Homework Administration Predicts Outcome For Individuals Diagnosed With Severe Mental Illness, Peter Kelly, Frank Deane
Systematic Homework Administration Predicts Outcome For Individuals Diagnosed With Severe Mental Illness, Peter Kelly, Frank Deane
Peter Kelly
No abstract provided.