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Metabolic Aspects Of Oryzanol In Rats, Michelle Smith Gillespie

LSU Master's Theses

Using a rat model, this study compared the bioavailability of three forms of oryzanol, a compound extracted from rice bran oil that has been associated with improved cholesterol levels. Various methods of extracting lipids from serum and liver were explored to determine oryzanol absorption. Cholesterol levels were obtained via enzymatic colorimetric assay and GCMS. Sprague Dawley retired female breeder rats were sustained for 11 weeks on a cholesterol-free diet to which either no oryzanol was added (n = 19) or 2.8 g/kg of oryzanol was added as: 7% oryzanol rice bran oil (RO, n = 8), crystalline oryzanol (CO, n …