Social and Behavioral Sciences Commons^™

Aberrant Epigenomic Modulation Of Glucocorticoid Receptor Gene (Nr3c1) In Early Life Stress And Major Depressive Disorder Correlation: Systematic Review And Quantitative Evidence Synthesis, Laurens Holmes Jr., Emily Shutman, Chinacherem Chinaka, Kerti Deepika, Lavisha Palaez, Kirk W. Dabney

Community & Environmental Health Faculty Publications

Early life stress (ELS) induced by psychological trauma, child maltreatment, maternal separation, and domestic violence predisposes to psycho-behavioral pathologies during adulthood, namely major depressive disorder (MDD), anxiety, and bipolar affective disorder. While environmental data are available in illustrating this association, data remain to be established on the epigenomic underpinning of the nexus between ELS and MDD predisposition. Specifically, despite the observed aberrant epigenomic modulation of the NR3C1, a glucocorticoid receptor gene, in early social adversity and social threats in animal and human models, reliable scientific data for intervention mapping in reducing social adversity and improving human health is required. We …

Mid-Atlantic Oil Spill Workshop: Are We Ready? A Regional Workshop As Part Of The National Academies And Sea Grant Collaborative Workshop Series, G. Walker, M. Covi

OES Faculty Publications

(First paragraph) In 2017, the Gulf Research Program (GRP) and the Health and Medical Division of the National Academies of Sciences, Engineering, and Medicine hosted a workshop to prepare for and respond to major marine oil spills. To address gaps identified at the workshop, GRP reached out to the Sea Grant Oil Spill Science Outreach Program to host a series of regional workshops. The Sea Grant Oil Spill team, based in the Gulf, partnered with state Sea Grant programs across the country to plan and deliver regional workshops in 2018-2019. The goals of the workshops were to raise awareness of …

Just Culture: It's More Than Policy, Linda Paradiso, Nancy Sweeney

Nursing Faculty Publications

[Description] Paradiso and Sweeney discuss the relationship between trust, just culture, and error reporting in medical care. Errors rarely occur in a vacuum, rather they're a sequence of events with multiple opportunities for correction. Clinical nurses can have a significant impact on reducing errors due to their proximity to patients. Just culture is a safe haven that supports reporting. In a just culture environment, organizations are accountable for systems they design and analysis of the incident, not the individual. The shift to a just culture is a slow process that takes years to develop and hardwire. Hospital-wide policies that incorporate …

Iron Deficiency Anemia, Population Health And Frailty In A Modern Portuguese Skeletal Sample, Samantha M. Hens, Kanya Godde, Kristin M. Macak

Sociology & Criminal Justice Faculty Publications

INTRODUCTION

Portugal underwent significant political, demographic and epidemiological transitions during the 20th century resulting in migration to urban areas with subsequent overcrowding and issues with water sanitation. This study investigates population health during these transitions and interprets results within a framework of recent history and present-day public health information. We investigate skeletal evidence for anemia (cribra orbitalia and porotic hyperostosis) as indicators of stress and frailty-i.e., whether the lesions contribute to susceptibility for disease or increased risk of death.

METHODS

The presence and severity of skeletal lesions were compared against known sex and cause of death data to investigate potential …