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Glial Cell Alterations In The Rat Medial Preoptic Area And Hippocampus As A Function Of Reproductive State, Gordon Wentworth Gifford

Master's Theses

Changes in reproductive state are accompanied by fluctuating levels of female gonadal hormones at higher levels and for longer periods of time than the normal estrus cycle. These hormones have been noted, in cell culture and over the regular estrus cycle, to influence structural changes in neurons and glial cells in areas of the brain associated with the conduct of maternal behavior. The purpose of this project was to characterize changes in GFAP immunoreactivity and astrocyte morphology in the mPOA and hippocampus as a function of reproductive state and female steroid hormone treatment. Results of this investigation noted an increases …