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Social and Behavioral Sciences Commons

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Psychology

Washington University in St. Louis

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Full-Text Articles in Social and Behavioral Sciences

Neuroticism And Stressful Life Events: Probing Mechanisms Underlying Vulnerability To Stress-Related Depression, Erin Bondy Dec 2019

Neuroticism And Stressful Life Events: Probing Mechanisms Underlying Vulnerability To Stress-Related Depression, Erin Bondy

Arts & Sciences Electronic Theses and Dissertations

Elevated neuroticism (N) potentiates the depressogenic effects of stressful life events (SLEs). We first replicate this association using longitudinal data (N=971 older adults) from the St. Louis Personality and Aging Network (SPAN) study. Here, SLEs prospectively predicted future depressive symptoms, especially among those reporting elevated N, even after accounting for prior depressive symptoms and previous SLE exposure (NxSLE interaction: p=0.016, ΔR2=0.003). These findings were further replicated in cross-sectional analyses of the Duke Neurogenetics Study (DNS), a young adult college sample with neuroimaging data (n=1,343: NxSLE interaction: p=0.019, ΔR2=0.003). Because evidence suggests that stress may promote depression …


Evaluation Of Neurobiological Risk Factors For Alcohol Consumption; Convergent Evidence For Predispositional Effects Of Brain Volume, David Baranger Aug 2018

Evaluation Of Neurobiological Risk Factors For Alcohol Consumption; Convergent Evidence For Predispositional Effects Of Brain Volume, David Baranger

Arts & Sciences Electronic Theses and Dissertations

Alcohol is one of the most widely used psychoactive substances and accounts for 5% of global disease burden. The goal of the present work is to help advance efforts to both identify prognostic markers of risk, and to understand the mechanisms by which alcohol consumption impacts health. Early life stress is one of the strongest predictors of mental illness, including alcohol dependence, and has been hypothesized to impact risk via modulation of striatal reward functions and reward learning. Studies examined the effect of stress on reward learning and processing, and tested for moderation by genetic and environmental risk. Results were …


Humans Integrate Monetary And Liquid Incentives To Motivate Cognitive Task Performance, Debbie Yee Dec 2015

Humans Integrate Monetary And Liquid Incentives To Motivate Cognitive Task Performance, Debbie Yee

Arts & Sciences Electronic Theses and Dissertations

It is unequivocal that a wide variety of incentives can motivate behavior. However, few studies have explicitly examined whether and how different incentives are integrated in terms of their motivational influence. The current study examines the combined effects of monetary and liquid incentives on cognitive processing, and whether appetitive and aversive incentives have distinct influences. We introduce a novel task paradigm, in which participants perform cued task-switching for monetary rewards that vary parametrically across trials, with liquid incentives serving as post-trial performance feedback. Critically, the symbolic meaning of the liquid was held constant (indicating successful reward attainment), while liquid valence …


Emotion Versus Motivation: Probing Dissociable Effects On Cognitive Control Through Task Performance, Pupillometry Methods, And Individual Differences, Kimberly Sarah Chiew Nov 2013

Emotion Versus Motivation: Probing Dissociable Effects On Cognitive Control Through Task Performance, Pupillometry Methods, And Individual Differences, Kimberly Sarah Chiew

All Theses and Dissertations (ETDs)

It is becoming increasingly appreciated that affective influences can contribute strongly to goal-oriented cognition and behaviour. However, much work is still needed to properly characterize these influences and the mechanisms by which they contribute to cognitive processing. An important question concerns the nature of emotional manipulations: i.e., direct induction of affectively valenced subjective experience) versus motivational manipulations: e.g., delivery of performance-contingent rewards and punishments) and their impact on cognitive control. Given previous empirical evidence suggesting that positive emotion may enhance cognitive flexibility and reactive control, while performance-contingent rewards may enhance goal maintenance and proactive control, we sought to directly compare …