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Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Psychology

Virginia Commonwealth University

2017

Depression

Articles 1 - 2 of 2

Full-Text Articles in Social and Behavioral Sciences

Alexithymia Moderates The Association Between Maternal Depressive Symptoms And Perceived Adolescent Adjustment, Hayne Noh Jan 2017

Alexithymia Moderates The Association Between Maternal Depressive Symptoms And Perceived Adolescent Adjustment, Hayne Noh

Undergraduate Research Posters

Rates of suicide among African American youth are increasing faster than any other ethnic group (Bridge et al., 2015). With mental illness associated with suicide rates, it is essential to understand how symptoms manifest during adolescence. Although the association between maternal depression and poor adolescent adjustment is well established, there is a dearth of evidence examining the impact of maternal alexithymia on adolescent adjustment, particularly among low-income youth. The goal of the study was to elucidate the role of maternal alexithymia (difficulty understanding and expressing emotion) in the association between maternal depressive symptoms and adolescent adjustment within a sample of …


Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith Jan 2017

Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith

Theses and Dissertations

Major depressive disorder (MDD) is a widespread psychiatric disorder that affects millions of people worldwide and is hypothesized to occur due to impairments in several neurotransmitter systems, including the monoaminergic and glutamatergic neurotransmitter systems. Antidepressant medications targeting multiple monoamine neurotransmitters have been shown to be effective for the treatment of depression. Racemic amisulpride is an atypical antipsychotic that has been used at low doses to treat dysthymia, a mild form of depression, and functions as an antagonist at DA2/3, 5-HT2B, and 5-HT7 receptors. Recent preclinical studies have suggested that the S(+) isomer may be more …