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Social and Behavioral Sciences Commons™
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University of Nebraska - Lincoln
Appetitive reinforcement; drug discrimination; Pavlovian conditioning; response magnitude; tobacco; stimulus salience
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Full-Text Articles in Social and Behavioral Sciences
Nicotine-Evoked Conditioned Responding Is Dependent On Concentration Of Sucrose Unconditioned Stimulus, Jennifer E. Murray, Rachel D. Penrod, Rick A. Bevins
Nicotine-Evoked Conditioned Responding Is Dependent On Concentration Of Sucrose Unconditioned Stimulus, Jennifer E. Murray, Rachel D. Penrod, Rick A. Bevins
Department of Psychology: Faculty Publications
Previous studies have shown that the interoceptive nicotine conditional stimulus (CS) functions similarly to exteroceptive CSs such as lights or environments. For instance, the appetitive conditioned response (CR) evoked when nicotine is repeatedly paired with sucrose presentations (the unconditioned stimulus; US) is sensitive to changes in training dose (CS salience) and the contiguity between the CS effects and sucrose. The current study was conducted to extend this research by examining the possible role of US intensity in CR acquisition and maintenance. Rats were trained using one of four sucrose concentrations: 0, 4, 16, or 32% (w/v). On nicotine sessions (0.4 …