Social and Behavioral Sciences Commons^™

Birth Order And The Academic And Social Success Of College Students, Jessica Nissenbaum

Honors Capstone Projects - All

The purpose of the study of Birth Order and the Academic and Social Success of College Students was to examine the relationship between birth order and the academic and social experiences that students have during their college years. An ideal college experience involves students being actively engaged in what they are learning and having positive social interactions and support networks. Unfortunately, the college experiences of many students fall short of these expectations and they struggle to continue their pursuit of higher education. Depression has become a serious concern on college campuses. Understanding the birth orders that may create challenges in …

The Prefrontal Cortex: A Predictor Of Psychotic Symptoms In Children With 22q11.2 Deletion Syndrome?, Nicole Addonizio

Honors Capstone Projects - All

Up to 30% of young adults with velocardiofacial syndrome (VCFS; 22q11.2 Deletion Syndrome) develop schizophrenia or psychosis. As a result, identifying the neuroanatomic trajectories that increase risk for psychosis in youth with VCFS is of great interest. Pinpointing a specific subregion of the brain that has a pattern of change in VCFS could aid in further research of schizophrenia and help to distinguish neuroanatomic changes.

In this study, high-resolution anatomic magnetic resonance brain images and measures of psychiatric function (i.e. symptoms of psychosis) were recorded in 40 youth with VCFS, 14 unaffected siblings, and 19 age-matched community control subjects at …

Drd2 Polymorphisms Imparting Risk For Schizophrenia, Lauren Paish

Honors Capstone Projects - All

Schizophrenia is a disorder that affects 1% of the population and causes enormous deficits in functioning. The development of this disorder is through unclear mechanisms, yet studies suggest that genetics and dopamine processes play a major role in the manifestation of schizophrenia. This study considers the gene that encodes dopamine receptor D2 (DRD2) and how single nucleotide polymorphisms (SNPs) affect alternative splicing of the gene and the balance between the two different protein isoforms, Long (D2L) and Short (D2S). Four mutations (rs12363125 and rs2511521 from intron 5 and rs6275 and rs6277 from exon 7) were studied. Constructs were derived …