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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Spatial-Relational Learning And Memory Deficits Associated With Nmdar Autoantibodies In Systemic Lupus Erythematosus, Brittany L. Bascetta
Spatial-Relational Learning And Memory Deficits Associated With Nmdar Autoantibodies In Systemic Lupus Erythematosus, Brittany L. Bascetta
Dissertations, Theses, and Capstone Projects
Individuals with Systemic Lupus Erythematosus (SLE) experience inflammation that may target any organ within the body, including the central and peripheral nervous systems. Additionally, these individuals often demonstrate psychological dysfunctions including emotional and cognitive deficits; however, research is inconsistent as to the nature and cause of these dysfunctions. While there are multiple factors that may increase risk for variability in cognitive function, such as population differences, socioeconomic status (SES), mood disorders (depression and anxiety), medication effects, and disease activity, these factors do not reliably predict the severity and extent of cognitive deficits. A growing body of animal research associates autoantibodies …
Microglial Location, Morphology, And Cognitive Performance In Mold-Exposed Mice, Karen Marmon
Microglial Location, Morphology, And Cognitive Performance In Mold-Exposed Mice, Karen Marmon
Theses and Dissertations
We examined changes in brain microglia and cognitive performance following mold exposure and doxycycline administration. Neither mold nor doxycycline caused significant changes in microglial location or morphology. While greater numbers of microglia in control-treated mice were linked with improved performance, greater numbers in mold-treated mice were linked to memory impairments.