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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Suppression Of Locomotor Activity In Female C57bl/6j Mice Treated With Interleukin-1Β: Investigating A Method For The Study Of Fatigue In Laboratory Animals, David R. Bonsall, Hyunji Kim, Awa Ndiaye, Abbey Petronzio, Grace Mckay-Corkum, Penny C. Molyneux, Thomas E. Scammell, Mary E. Harrington
Suppression Of Locomotor Activity In Female C57bl/6j Mice Treated With Interleukin-1Β: Investigating A Method For The Study Of Fatigue In Laboratory Animals, David R. Bonsall, Hyunji Kim, Awa Ndiaye, Abbey Petronzio, Grace Mckay-Corkum, Penny C. Molyneux, Thomas E. Scammell, Mary E. Harrington
Psychology: Faculty Publications
Fatigue is a disabling symptom in patients with multiple sclerosis and Parkinson’s Disease, and is also common in patients with traumatic brain injury, cancer, and inflammatory disor- ders. Little is known about the neurobiology of fatigue, in part due to the lack of an approach to induce fatigue in laboratory animals. Fatigue is a common response to systemic challenge by pathogens, a response in part mediated through action of the pro-inflammatory cytokine interleukin-1 beta (IL-1β). We investigated the behavioral responses of mice to IL-1β. Female C57Bl/6J mice of 3 ages were administered IL-1β at various doses i.p. Interleukin-1β reduced locomotor …
Anticipatory Coarticulation Facilitates Word Recognition In Toddlers, Tristan Mahr, Brianna T.M. Mcmillan, Jenny R. Saffran, Susan Ellis Weismer, Jan Edwards
Anticipatory Coarticulation Facilitates Word Recognition In Toddlers, Tristan Mahr, Brianna T.M. Mcmillan, Jenny R. Saffran, Susan Ellis Weismer, Jan Edwards
Psychology: Faculty Publications
Children learn from their environments and their caregivers. To capitalize on learning opportunities, young children have to recognize familiar words efficiently by integrating contextual cues across word boundaries. Previous research has shown that adults can use phonetic cues from anticipatory coarticulation during word recognition. We asked whether 18-24. month-olds (n= 29) used coarticulatory cues on the word "the" when recognizing the following noun. We performed a looking-while-listening eyetracking experiment to examine word recognition in neutral vs. facilitating coarticulatory conditions. Participants looked to the target image significantly sooner when the determiner contained facilitating coarticulatory cues. These results provide the first evidence …