Social and Behavioral Sciences Commons^™

Variables Associated With Patient Activation In Persons With Multiple Sclerosis, Marie-Christine Rutter Goodworth, Lara Stepleman, Judith Hibbard, Lisa Johns, Dustin Wright, Mary D. Hughes, Mitzi J. Williams

Faculty Publications - Doctor of Psychology (PsyD) Program

Identifying variables associated with patient activation in the multiple sclerosis population could serve to facilitate better multiple sclerosis self-management behaviors. Using a cross-sectional survey design, 199 participants were recruited from a multiple sclerosis center in the Southeastern United States. Depression, multiple sclerosis quality of life, and multiple Sclerosis self-efficacy were all significantly correlated with patient activation. Results of a hierarchical regression indicated that patient activation was significantly related to educational attainment, depression, and self-efficacy but not to quality of life. The results suggest several possible targets for intervention to increase patient activation, including health literacy, depression symptoms, and self-efficacy for …

A Longitudinal Study Evaluating The Effects Of Interferon-Alpha Therapy On Cognitive And Psychiatric Function In Adults With Chronic Hepatitis C, Marilyn Huckans, Bret Fuller, Viva Wheaton, Sarah Jaehnert, Carilyn Ellis, Michael Kolessar, Daniel Kriz, Jeanne Renee Anderson, Kristin Berggren, Hannah Olavarria, Anna W. Sasaki, Michael Chang, Kenneth D. Flora, Jennifer M. Loftis

Faculty Publications - Doctor of Psychology (PsyD) Program

Objective: To prospectively evaluate for changes in objective cognitive performance (attention, memory, and executive function) and psychiatric symptom severity (depression, anxiety, fatigue, and pain) in patients before, during and after interferon-alpha based therapy (IFN) for chronic hepatitis C virus infection (HCV).

Methods: 33 HCV+ adults were evaluated two months before IFN initiation (baseline), three months into IFN, and six months following IFN termination (IFN+ Group). 31 HCV+ adults who did not undergo IFN therapy were evaluated at baseline and six months later (IFN− Group). At each evaluation, participants completed the Neuropsychological Assessment Battery (NAB) Attention, Memory and Executive Functions Modules, …