Social and Behavioral Sciences Commons^™

Taking The Perspective That A Depressive State Reflects Inflammation: Implications For The Use Of Antidepressants, Jill Littrell

jill l littrell Dr.

This paper reviews both the evidence that supports the characterization of depression as an inflammatory disorder and the different biochemical mechanisms that have been postulated for the connection between inflammation and depression. This association offers credible explanation for the short term efficacy of antidepressants, which have short term anti-inflammatory effects. Evidence for those anti-inflammatory effects is discussed. Evidence of the contrary long-term effects of antidepressants, which increase rather than decrease inflammation, is also reviewed. It is argued that this increase in inflammation would predict an increase in chronicity among depressed patients that have been treated with antidepressants drugs, which has …

Effect Of Apolipoprotein Ε4 On Hippocampal And Brain Volume In Intractable Temporal Lobe Epilepsy, Robyn Busch, Darlene Floden, Tara Lineweaver, Jessica Chapin, Kanjana Ungwongse, Tim Wehner, Ramon Diaz-Arrastia, Imad Najm

Tara T. Lineweaver

This study investigated the relationship between the apolipoprotein (APOE) ε4 allele and brain volumes in patients with medically intractable temporal lobe epilepsy (TLE). MRI-based volumetric analyses of the hippocampi, cerebral hemispheres, and whole brain were conducted in 59 patients with TLE (31 with left TLE, 28 with right TLE) with hippocampal sclerosis (HS). There were no differences in hippocampal, hemispheric, or whole brain volumes as a function of ε4 status even after correcting for hemispheric and total brain volumes. However, APOE ε4 carriers showed a trend toward having a smaller discrepancy between ipsilateral and contralateral hippocampal volumes than patients without …

Implementing The Massachusetts Child Trauma Project (Mctp) To Improve Services For Children With Complex Trauma In Child Welfare: Phase I Needs And Readiness Assessment, Charmaine B. Lo, Melodie Wenz-Gross, Jessica L. Griffin

Melodie Wenz-Gross

MCTP seeks to improve placement stability and outcomes for children with complex trauma in the care of the Massachusetts Department of Children and Families (DCF) by creating a sustainable capacity for providing evidence-based trauma interventions within provider agencies, and trauma-informed practices within DCF.

In-Hospital Depression Predicts Early Hospital Readmission After An Acute Coronary Syndrome: Preliminary Data From Trace-Core, David Mcmanus, Jane Saczynski, Molly Waring, Milena Anatchkova, Richard Mcmanus, Robert Goldberg, Jeroan Allison, David Parish, Hamza Awad, Jerry Gurwitz, Arlene Ash, Catarina Kiefe

Richard H. McManus

Background: Hospital systems, patients and providers seek to avert rehospitalizations within 30 days for patients admitted with an acute coronary syndrome (ACS). Rehospitalizations within 30 days of discharge are often considered preventable and to reflect poor in-hospital management or discharge practices. However, independent associations of psychosocial factors with early rehospitalization in patients admitted with an ACS have not been examined. Methods: A multi-racial cohort of 1,540 patients admitted with an ACS reported psychosocial factors via standardized questionnaires in an in-hospital interview. One month following discharge, patients were interviewed via phone and reported hospital readmissions. We used logistic regression models to …

39. Young Children’S Difficulty With Indirect Speech Acts: Implications For Questioning Child Witnesses, Angela D. Evans, Stacia N. Stolzenberg, Kang Lee, Thomas D. Lyon

Thomas D. Lyon

“Young People These Days, Are Not Like We Used To Be ... #11;Or Are They?”, Harry B. Mayr

harry b mayr

No abstract provided.

An Introduction To Drugs And The Neuroscience Of Behavior, Adam Prus

Adam J Prus

This up-to-date new text provides an introductory overview of the nervous system actions and behavioral effects of the major classes of psychoactive drugs. Appropriate for undergraduate students who have an introductory level background in psychology or other areas within the social sciences, AN INTRODUCTION TO DRUGS AND THE NEUROSCIENCE OF BEHAVIOR illustrates concepts and highlights research techniques. The book's most important feature is its pedagogical elements, which are not found in other psychopharmacology texts, but are particularly important for making this specialized topic approachable for undergraduates. Charts and diagrams illustrate basic concepts and processes important for understanding the actions and …

Honorable Mention: 27th Annual No Big Heads Exhibition, Adam Prus

Adam J Prus

This up-to-date new text provides an introductory overview of the nervous system actions and behavioral effects of the major classes of psychoactive drugs. Appropriate for undergraduate students who have an introductory level background in psychology or other areas within the social sciences, AN INTRODUCTION TO DRUGS AND THE NEUROSCIENCE OF BEHAVIOR illustrates concepts and highlights research techniques. The book's most important feature is its pedagogical elements, which are not found in other psychopharmacology texts, but are particularly important for making this specialized topic approachable for undergraduates. Charts and diagrams illustrate basic concepts and processes important for understanding the actions and …

Interactions Of Borderline Personality Disorder And Mood Disorders Over Ten Years, John G. Gunderson, Robert L. Stout, M. Tracie Shea, Carlos M. Grilo, John C. Markowitz, Leslie C. Morey, Charles A. Sanislow, Shirley Yen, Mary C. Zanarini, Alex S. Keuroghlian, Thomas H. Mcglashan, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

Objective: To examine the relationship of borderline personality disorder (BPD) to mood disorders by using data from the Collaborative Longitudinal Personality Disorders Study on the reciprocal interactions of BPD with both depressive and bipolar disorders over the course of 10 years.

Method: The study included 223 BPD patients with DSM-IV–defined co-occurring major depressive disorder (MDD) (n = 161), bipolar I disorder (n = 34), and bipolar II disorder (n = 28) who were reliably and prospectively assessed over a period of 10 years between 1997 and 2009. Proportional hazards regression analyses were used to assess the effects of improvement or …

Mental Health Systems Transformation Through Participatory Research And Action: The Young Adult Appreciative Inquiry/Photovoice Project, Thomas M. Laporte, Mason G. Haber, Damie Jackson - Diop, Brittany Holt

Mason G. Haber

Participatory action research and evaluation methods (PAR) have been used to help individuals to address a variety of challenges and improve the responsiveness of service systems to these challenges. To the present, however, few studies have examined applications of PAR in systems change advocacy for youth with mental health needs in the transition to adulthood (transition-age youth [TAY]). PAR may be especially beneficial in systems transformation efforts for this population, which lacks resources of other mental health system consumers for advocacy such as formal settings, specialized professional attention, and well established consumer organizations. The present paper describes how specific strategies …

Risk, Vulnerability And Resilience: An Epigenetic Trajectory Of Psychiatric Disorders, Amresh Srivastava

Amresh Srivastava

ABSTRACT: Risk, Vulnerability and Resilience: An epigenetic trajectory of psychiatric disorders Amresh Shrivastava. Biopsychosocial model is generally widely accepted for pathogenesis of mental disorder, recent research shows a different concept. . Social, cultural, environmental factors possibly interact in a complex way to give rise to behavioral symptoms in a particular disorder. Such factors are considered 'risk factors'. but their discrete role in causation of illness is less clear. Two main factors appear to play important role which may partially explain this process. 1. risk-vulnerability and stress diathesis model and the 2. Gene-environment interaction. Both may be operating simultaneously. Our understanding …

Predictors Of Posttraumatic Stress Disorder, Depression, And Suicidal Ideation Among Canadian Forces Personnel In A National Canadian Military Health Survey, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon Elhaid, J. Richardson

Bradley Corbett

Despite efforts to elucidate the relationship between traumatic event exposure and adverse mental health outcomes, our ability to understand why only some trauma-exposed individuals become emotionally affected remains challenged. The aim of the current study is to determine the relations between social support, religiosity, and number of lifetime traumatic events experienced on past-12 month posttraumatic stress disorder (PTSD), depression, and suicidal ideation (SI) in a nationally representative sample of Canadian Forces personnel. The current study used data from the Canadian Community Health Survey Cycle 1.2 – Canadian Forces Supplement. The impact of a number of predictive and mediating factors was …

Preventing Mental Distress In The Military, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon D. Elhai, J. Donald Richardson

Bradley Corbett

No abstract provided.

Biological Psychiatry: A Practice In Search Of A Science, W. Joseph Wyatt, Donna M. Midkiff

W. Joseph Wyatt

The rise of the biological causation model in the past thirty years is traced to psychiatry’s efforts to regain lost status and to protect itself from intrusions by non-medical practitioners, as well as to the pharmaceutical industry’s drive for profits. Evidence in support of the model, including studies of identical twins and of brain structure and function, are less revealing than was earlier thought, due to problems in methodology and interpretation. Organized psychiatry, when challenged in 2003, was unable to provide compelling evidence for biological causation of most mental and behavioral disorders. A paradigm shift away from biological causation and …

Six-To-One Gets The Job Done: Comments On The Reviews, W. Joseph Wyatt, Donna M. Midkiff

W. Joseph Wyatt

We are pleased to note that six of the seven responses to our article were marked by approval, and/or thoughtful contemplation, regarding our central theses—that the research said to support biological causation of mental disorders is relatively weak, and that the claims of drug effectiveness are often overstated.

Psychiatry’S Thirty-Five-Year, Non-Empirical Reach For Biological Explanations, W. Joseph Wyatt, Donna M. Midkiff

W. Joseph Wyatt

This is our third article in a series that began with a special issue of Behavior and Social Issues in 2006. Here we briefly review our central points from the first two articles. First is that over the past thirty-five years, claims of biological causation of mental and behavioral disorders have gone well beyond the research data, for reasons that are largely related to psychiatry’s lost esteem and protection of its “turf,” as well as to the financial interests of the pharmaceutical industry. Our second position is that claims of psychotropic drugs’ effectiveness have been overstated. We respond, as well, …

Heroes: What They Do & Why We Need Them, Scott T. Allison, George R. Goethals

Scott T. Allison

Abraham Lincoln, Princess Diana, Rick in Casablanca--why do we perceive certain people as heroes? What qualities do we see in them? What must they do to win our admiration? In Heroes, Scott T. Allison and George R. Goethals offer a stimulating tour of the psychology of heroism, shedding light on what heroism and villainy mean to most people and why heroes--both real people and fictional characters--are so vital to our lives. The book discusses a broad range of heroes, including Eleanor Roosevelt, Walt Kowalski in Gran Torino, Senator Ted Kennedy, and explorer Ernest Shackleton, plus villains such as Shakespeare's Iago. …

Need For Newer Experiments In Strengthening Education And Training Human Resource Development For Suicide Prevention, Amresh Srivastava

Amresh Srivastava

Suicide is a global public health problem and one of the leading causes of premature death for all ages. Studies show that only 25% suicide has been within health care system, we have no information about the rest 75%. To bring more people at risk for suicide is an urgent requirement which makes a strong argument education and awareness.The WHO acknowledged that suicide prevention requires intervention from outside the health sector and calls for an innovative, comprehensive multi-sectorial approach, including both health and non-health sectors, e.g. education, labor, police, justice, religion, law, politics, the media. . Early identification of at-risk …