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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
The Effects Of Physical Function And Genetics On Cognition And Blood Biomarkers In Individuals At-Risk For Alzheimer’S Disease And Related Dementias, Joshua Louis Gills
The Effects Of Physical Function And Genetics On Cognition And Blood Biomarkers In Individuals At-Risk For Alzheimer’S Disease And Related Dementias, Joshua Louis Gills
Graduate Theses and Dissertations
Alzheimer’s disease and related dementia (ADRD) rates are expected to triple by the year 2050. Early detection and specific mitigation efforts are warranted to blunt the alarming rate. Physical function (PF) declines with age, but higher physical function is associated with better cognitive functioning in middle-to- older age individuals. Moreover, greater physical activity (PA) is associated with better global cognition; however, Apoliporotein e4 carriers may not gain the same benefits with exercise. Additionally, plasma phosphorylated tau 217 (p-tau217) has been identified as a novel diagnostic ADRD biomarker which needs further research to examine associations with risk factors. Therefore, the aims …
Negative Urgency's Influence On State-Level, Emotion-Based Changes In Alcohol-Related Cognitions, Noah Wolkowicz
Negative Urgency's Influence On State-Level, Emotion-Based Changes In Alcohol-Related Cognitions, Noah Wolkowicz
Graduate Theses and Dissertations
This project expanded on the Acquired Preparedness Model of Risk (APMR) by examining how Negative Urgency (NU), the tendency to act rashly in negative emotional states, affects emotion-based changes in alcohol cognitions to produce risk for alcohol use. The APMR prioritizes the role of outcome expectancies as the means through which traits such as NU, convey alcohol use risk. However, this model treats these cognitions as static and often fails to assess their valence; further, alcohol-cognitions fluctuate in response to negative emotions and may become more salient during these states. Therefore, this study examined: 1) how NU impacts negative emotion-based, …