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Full-Text Articles in Social and Behavioral Sciences

Characterizing Mekk1: Candidate Behavioural Isolation Gene, Caryn Dooner Nov 2017

Characterizing Mekk1: Candidate Behavioural Isolation Gene, Caryn Dooner

Electronic Thesis and Dissertation Repository

Behavioural isolation can occur due to divergence in aspects of courtship and mating, and can contribute to reproductive isolation. The purpose of this study is to determine how a gene, Mekk1, contributes to female rejection behaviour between D. melanogaster and D. simulans. Unique polymorphisms were identified within D. simulans Mekk1 that could contribute to behaviour, most of which are non-coding. Both transcripts of Mekk1 appear to be expressed at similar levels in D. simulans and D. melanogaster. These data also indicate that Mekk1 may be expressed in a specific region of the brain called the mushroom body, …


The Neural Mechanisms Underlying The Perception And Production Of Learned Vocalizations In Songbirds, Shannon Katie Mischler Oct 2017

The Neural Mechanisms Underlying The Perception And Production Of Learned Vocalizations In Songbirds, Shannon Katie Mischler

Electronic Thesis and Dissertation Repository

Songbirds produce a wide array of vocalizations, including song, and learned and innate calls. Songs and calls can be functionally defined. Songs are typically used to attract potential mates and defend one’s territory, whereas calls are used for everything else, such as advertising the presence of a predator, or location of a food source, and maintaining contact with members of one’s flock. The purpose of this thesis was to better understand the neural mechanisms underlying call production and perception in two songbird species; the black-capped chickadee (Poecile atricapillus) and the zebra finch (Taeniopygia guttata). My objectives …


A Diffusion Tensor Imaging Study Of Motor Fibre Path Integrity And Overt Responsiveness In Disorders Of Consciousness, Clara A. Stafford Aug 2017

A Diffusion Tensor Imaging Study Of Motor Fibre Path Integrity And Overt Responsiveness In Disorders Of Consciousness, Clara A. Stafford

Electronic Thesis and Dissertation Repository

This study investigated the relationship between motor thalamo-cortico-cerebellar fibre path integrity and overt responsiveness in patients with disorders of consciousness (DOC). Additionally, we investigated the potential of imaging these motor tracts at ultra-high fields. Study I and II aimed to map the white matter connections of motor execution fibres in DOC patients. Our results showed significant reductions in motor fibre path integrity across DOC diagnostic categories. Study III and IV aimed to develop a 7T MRI Diffusion Tensor Imaging (DTI) sequence. We optimized this sequence to image motor fibre paths in DOC patients. We concluded that, in healthy controls, probabilistic …


An Investigation Of Propranolol As An Agent For The Experimental Manipulation Of Interoception., Jane Evguenia Kouptsova Aug 2017

An Investigation Of Propranolol As An Agent For The Experimental Manipulation Of Interoception., Jane Evguenia Kouptsova

Electronic Thesis and Dissertation Repository

Interoception has recently come under research focus as a potential influence on emotional and epistemic feelings. However, existing means to manipulate it experimentally have conceptual or logistical drawbacks. We investigated whether 20 mg of propranolol is a viable agent for experimentally manipulating interoception. Thirteen participants completed a double-blind, placebo-controlled crossover study, performing two heartbeat perception tasks, control tasks and measures of anxiety and alertness. All measures were obtained at the beginning and end of both sessions. Propranolol significantly decreased heart rate and systolic blood pressure. Heartbeat detection performance numerically decreased under propranolol, although this effect failed to reach statistical significance. …


The Influence Of Estrogen On Sex Differences In Chemotherapy-Induced Nausea And Vomiting (Cinv), Danna L. Zevy Apr 2017

The Influence Of Estrogen On Sex Differences In Chemotherapy-Induced Nausea And Vomiting (Cinv), Danna L. Zevy

Electronic Thesis and Dissertation Repository

Chemotherapy-induced nausea and vomiting (CINV) is one of the most distressing events that affects the quality of life of cancer patients. Evidence suggests that females are more susceptible to CINV than males, but the mechanism remains unknown. The current thesis examined whether higher levels of circulating estrogens in females contributes to this sex difference. CINV was analyzed in a pediatric oncology population, where it was revealed female patients demonstrate increased delayed CINV relative to male patients, in the post-pubertal age group. CINV was also studied by examining the influence of the estrous cycle on anticipatory nausea (AN) in rats. This …


Transcranial Magnetic Stimulation To Assess Motor System Excitability Fluctuations During Auditory Anticipation And Beat Perception, Johannes G.P Teselink Apr 2017

Transcranial Magnetic Stimulation To Assess Motor System Excitability Fluctuations During Auditory Anticipation And Beat Perception, Johannes G.P Teselink

Undergraduate Honors Theses

Humans tend to spontaneously move to the regular beat of musical rhythm. Beat perception is the tendency to sense and anticipate the regular time positions (beats) that movements synchronize with. The neural motor system plays an important role in beat perception, but the dynamics of excitability in the motor system associated with beat perception have not been characterized. This project investigated motor system excitability fluctuations using transcranial magnetic stimulation and electromyography during perception of beat-based and non-beat-based rhythms. We applied single-pulse TMS over the left primary motor cortex of healthy participants as they listened to three types of rhythms that …