Social and Behavioral Sciences Commons^™

An Ewas Of Dementia Biomarkers And Their Associations With Age, African Ancestry, And Ptsd, Mark W. Miller, Erika J. Wolf, Xiang Zhao, Mark W. Logue, Sage E. Hawn

Psychology Faculty Publications

Background

Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the influences of PTSD, APOE ε4 genotypes, DNA methylation, and other variables on the age- and dementia-associated biomarkers Aβ40, Aβ42, GFAP, NfL, and pTau-181 measured in plasma. Our primary hypothesis was that PTSD would be associated with elevated levels of these markers.

Methods

Analyses were based on data from a PTSD-enriched cohort of 849 individuals. We began by performing factor analyses of the biomarkers, the results of which …

Affective Depression Mediates Ptsd To Suicide In A Sample Of Treatment-Seeking First Responders, James Whitworth, Jeanine Galusha, Jose Carbajal, Warren Ponder, Donna Schuman

Faculty Publications

Objective: The aim of this study was to examine the associations of comorbid

posttraumatic stress disorder (PTSD), affective or somatic depression, and

suicide among first responders (FRs). Method: We used baseline data from

FRs (N = 232) who sought services at a nonprofit mental health agency specializing

in treating trauma exposed FRs. We conducted two PROCESS simple

mediation models with PTSD as the predictor, affective depression and somatic

depression as the mediators, and suicidality as the dependent variable.

Results: Affective depression significantly mediated the relationship between

PTSD and suicidality, whereas somatic depression did not. The direct effect …

Ptsd And Alcohol Use Disorders Predict The Pace Of Cellular Aging, Sage E. Hawn, Xiang Zhao, Mark W. Miller, Sara Wallander, Christine Govan, Anjanette Stone, Steven A. Schichman, Mark W. Logue, Erika J. Wolf

Psychology Faculty Publications

Advanced epigenetic age is associated with psychopathology and may help to explain the link between psychopathology and physical health morbidity and mortality. Using a longitudinal sample of 171 trauma-exposed Veterans, we modeled the rate of change in epigenetic age across two time points (averaging 5.58 years apart) using two epigenetic age algorithms (GrimAge and Horvath) and tested associations with posttraumatic stress disorder (PTSD), alcohol use disorder (AUD), and depression. Results showed that PTSD (β = .199) and AUD (β = .186) were associated with a quickened pace of epigenetic aging over time (ps < .021). Results replicate and extend prior work and offer foundational support for identifying interventions that slow the pace of biological aging among those with psychopathology.

Black Mental Health Clinicians' Experiences And Lessons From The Intersecting Crises Of Black Mental Health, Covid-19, And Racial Trauma: An Interpretive Phenomenological Study, Chanté Meadows

Antioch University Dissertations & Theses

This study explored the experiences of African American mental health clinicians’ during the intersecting crises of the Black mental health crisis, the highly publicized racial tension tied to extrajudicial violence and over-policing of Black Americans, and the COVID-19 pandemic. The pandemic started a global crisis that affected millions of people’s physical and mental health and overall well-being. Shared trauma explores the duality of mental health clinicians’ personal and professional experiences. Grounded in critical race theory and models of trauma, this study explores Black mental health clinicians’ lived experiences and lessons. This is an interpretive phenomenological study with narrative interviews of …

Resilience Is Low Among Both Military And Non-Military Populations With Post-Traumatic Stress Disorder, Kelsey Roberts, Janet Wilmoth, Shannon M. Monnat

Population Health Research Brief Series

Post-traumatic stress disorder (PTSD) affects the lives of 12 million people in the United States. While commonly thought of in relation to military personnel and veterans, PTSD is also common among the general public. Resilience - the ability to cope with stressful events - is essential for recovering from PTSD. This data slice uses data from the National Wellbeing Survey to examine resilience among U.S. working-age adults with and without PTSD by their relationship to the military. Results show that those with PTSD have less resilience than those who have not experienced PTSD. In addition, those with military experience are …

The Impact Of Trauma Subtypes On Ptsd Severity In Syrian Child And Adolescent Refugees, Liza Hinchey, Lana Grasser, Bassem Saad, Kathleen Gorski, Arash Javanbakht, May Chammaa

Medical Student Research Symposium

Background:

Child and adolescent refugee populations are at increased risk for psychiatric disorders including posttraumatic stress disorder (PTSD) and anxiety. Recent studies have demonstrated different symptomatology based on the type(s) of traumatic events experienced. Cluster analyses based on the Life Events Checklist (LEC) indicate three trauma subtypes: accidental/injury, victimization, and predominant death threat. Extending this line of research from adults to youth may lead to better understanding of the unique impacts of trauma subtypes on symptoms for improved prediction of risk and resilience.

Methods:

Refugee participants were recruited within 1 month of their resettlement in the U.S. Data used were …

Prevalence Of Bullying Behaviors Among Students From A National University In The United Arab Emirates: A Cross-Sectional Study, Fatima Al-Darmaki, Haleama Al Sabbah, Dalia Haroun

All Works

This study aims to investigate bullying behaviors among college students at one of the national universities in UAE, and also to examine the psychological characteristics of those who were exposed to, or have experienced bullying. A cross-sectional study was conducted on 839 undergraduate students at one of the national universities in the UAE. Students from all colleges participated in this study and were selected by using stratified random sampling. Participants completed a bullying survey designed for the study, in addition to three psychological measures [i.e., Aggression Questionnaire, Buss and Perry, 1992; The Primary Care Anxiety and Depression, El-Rufaie et al., …

Mental Health After Injury: How Neighborhoods Impact Recovery, Bryce Hruska, Maria Pacella-Labarbara, Ivan E. Castro, Richard L. George, Douglas L. Delahanty

Population Health Research Brief Series

Each year in the United States, there are over 90 million injury-related emergency department visits, resulting in $4.2 trillion in costs related to medical care, loss of work, and reduced quality of life. Nearly a quarter of injury survivors are diagnosed with a new mental health disorder within the first year of injury. This brief examines several aspects of neighborhood context and their relationship to PTSD symptom severity following an injury. Results show that survivors living in neighborhoods with higher racial segregation and lower socioeconomic status report higher PTSD symptom severity.

History, Cognition And Nostromo: Conrad’S Explorations Of Torture, Trauma, And The Human Rage For Order, Richard Ruppel

English Faculty Articles and Research

Focusing on Joseph Conrad’s Nostromo, this essay historicizes the treatment of what we now call post-traumatic stress disorder, demonstrating how Conrad anticipated our current understanding and treatment of the illness. The second part of the essay addresses Nostromo’s treatment of historiography. Part three is concerned with epistemology and the relationship between neurological discoveries concerning the gap between perception and consciousness, relating those discoveries to Conrad’s use of delayed decoding.

Ptsd Perceptions In U.S. Military Members And Their Families: A Qualitative Study, Jennifer L. Thomson

Psychology Educator Scholarship

Post-traumatic stress disorder (PTSD) is a chronic and debilitating disorder characterized by hypervigilance and recurrent, intrusive memories of the traumatic event. Estimates for lifetime prevalence of PTSD diagnoses for United States military personnel vary widely from 10% to more than 30%. The current study aimed to investigate the attitudes and beliefs regarding PTSD and its diagnosis and treatment within U.S. military service members and their families. An online survey was administered to current and former members of the U.S. military and members of their immediate families. The results revealed low levels of mental health stigma and positive attitudes toward treatment …

Development And Validation Of A Measure Of Birth-Related Ptsd For Fathers And Birth Partners: The City Birth Trauma Scale (Partner Version), Rebecca Webb, Ann M. Smith, Susan Ayers, Daniel B. Wright, Alexandra Thornton

Educational Psychology, Leadership, and Higher Education Faculty Research

Research suggests that some fathers and birth partners can experience post-traumatic stress disorder (PTSD) after witnessing a traumatic birth. Birth-related PTSD may impact on many aspects of fathers’ and birth partners’ life, including relationship breakdown, self-blame and reducing plans for future children. Despite the potential impact on birth partners’ lives there is currently no measure of birth-related PTSD validated for use with birth partners. The current study therefore adapted the City Birth Trauma Scale for use with birth partners. The City Birth Trauma Scale (Partner version) is a 29-item questionnaire developed to measure birth-related PTSD according to DSM-5 criteria: stressor …

Exploring Attentional And Emotional Biases As A Function Of Trauma And Dissociation Symptomology, Claudia Clinchard

Department of Psychology: Dissertations, Theses, and Student Research

There is evidence that threatening facial expressions (e.g., angry faces) direct attention toward the target, and that for facial expressions that are less threatening but still convey negative valence (e.g., fear faces) direct attention outward and to one’s environment, therefore causing a shift in memory performance and attentional bias depending on the level of threat in emotional facial expressions presented. Extant literature provides evidence for attentional biases both towards and away from threat in those with posttraumatic stress disorder (PTSD) symptomology. The current study aimed to replicate the previous findings of the effects stimulus and emotion have on memory performance …

Incorporating Psychological Trauma Into Adhd Differentials: A Pilot Study Of Primary Care Providers' Perspectives, Amber Nipper

PsyD Program in Clinical Psychology Doctoral Dissertations (Seattle)

According to the American Academy of Pediatrics (AAP, n.d.), 40% to 50% of individuals seeking mental health services terminate prematurely due to lack of access, lack of transportation, financial constraints, child mental health professional shortages, and stigma related to mental health. These barriers contribute to primary care providers assessing and managing mental health concerns at increasing rates, particularly symptoms consistent with attention deficit/hyperactivity disorder (ADHD). ADHD is a neurobiological disorder beginning in childhood that is defined as “a persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development” (American Psychiatric Association [APA], 2013, p. 59). Current literature shows …

The Network Structure Of Posttraumatic Stress Disorder Among Filipina Migrant Domestic Workers: Comorbidity With Depression, Melissa R. Garabiles, Chao K. Lao, Brian J. Hall

Psychology Department Faculty Publications

Background

Labour migrants are exposed to potentially traumatic events throughout the migration cycle, making them susceptible to developing mental disorders. Posttraumatic stress disorder (PTSD) is often comorbid with depression. Comorbidity worsens the course of illness, prognosis, treatment response, and increases suicidal risk. Using network analysis, this study examined the structure of PTSD and depression in a sample of migrant domestic workers, an especially vulnerable community of labour migrants. This study sought to derive the central or most important symptoms, strongest edges or relationships among symptoms, and bridge symptoms between PTSD and depression.

Methods

Data were obtained from 1,375 Filipina domestic …

Risk And Protective Factors Of Dementia Among Adults With Post-Traumatic Stress Disorder: A Systematic Review Protocol, Karen A. Lawrence, Theresia M. Pachner, Molly M. Long, Stephanie Henderson, Donna L. Schuman, Brenda L. Plassman

Social Work Faculty Publications

INTRODUCTION: Post-traumatic stress disorder (PTSD) is associated with an increased risk of dementia. Individual epidemiological studies have controlled for several confounders of the relationship between PTSD and increased dementia risk, yet particular risk factors underlying this relationship have not been determined. This systematic review protocol aims to identify risk and protective factors of dementia among adults with PTSD.

METHODS AND ANALYSIS: We will conduct an electronic search of the databases: PubMed, CINAHL, PsychINFO, The Cochrane Library, Scopus and ProQuest Dissertation and Theses Global. After screening the studies, quantitative synthesis will be performed, if possible. Otherwise, a narrative synthesis will be …

Is Eye Movement Desensitization And Reprocessing Worth It? A Pragmatic Analysis For Clinicians, Brandon P. Cvengros

Psychology Capstone Projects

Eye movement desensitization and reprocessing is a treatment developed for post-traumatic stress disorder (PTSD) that combines the cognitive processing of trauma with bilateral eye movements (EMs). Research has demonstrated that EMDR can be an efficacious treatment for PTSD. Other common treatments for PTSD include cognitive behavioral therapy (CBT) and exposure therapy (ET). Research has demonstrated that both CBT and ET are efficacious in the treatment of PTSD. EMDR is a controversial treatment, with critics stating that it is very similar to ET and that the novel component, EMs, are irrelevant to treatment outcomes. EMDR has additional time and financial costs, …

A Therapeutic Pastoral Counseling Program Designed To Reveal And Treat Combat Events Of Homeless Veterans In Wake County, North Carolina, Earnest Lee Shannon Jr

Doctoral Dissertations and Projects

This thesis project researched homelessness among male veterans in Wake County, North Carolina to determine if they experienced a combat event that caused spiritual injury caused by moral injury and shame, which contributed to their homelessness. Joshua’s Conquest, the spiritual formation treatment program is used to treat the spiritual injury. The need for this program is explicated, along with the development of Joshua’s Conquest, and how it will treat this odious event, so the homeless male veteran will be able to obtain housing normalcy. Personally, this thesis project was fueled by experiences with homelessness and limited service in the military. …

Mental Health Problems Of The Youngest Generation Of American Veterans (Problemy Zdrowia Psychicznego Najmłodszego Pokolenia Weteranów Amerykańskich), Jaroslaw Richard Romaniuk

Faculty Scholarship

Wartime activities determine the threats to a soldier’s life and health. To prepare soldiers for a new forms of warfare, one should know the challenges the soldier faces in the midst of battle and after returning home. From 2001 to 2015, 1.2 million American soldiers returning from Iraq and Afghanistan used the health care services of the Department of Veterans’ Affairs. An analysis of the resulting medical interventions makes possible a long term evaluation of the effects of war, some of which appear only after the soldier returns to civilian life. This study analyzes the research on the mental health …

Depression, Anxiety, Post-Traumatic Stress Disorder And A History Of Pervasive Gender-Based Violence Among Women Asylum Seekers Who Have Undergone Female Genital Mutilation/Cutting: A Retrospective Case Review, Hazel Lever, Deborah Ottenheimer, Jimmitti Teysir, Elizabeth Singer, Holly G. Atkinson

Publications and Research

We sought to evaluate the frequency of anxiety, depression, PTSD, and any experiences of violence in women who had undergone Female Genital Mutilation/Cutting (FGM/C) and were seeking asylum in the United States. We undertook a retrospective qualitative descriptive study of FGM/C cases seen in an asylum clinic over a 2-year period. Standardized questionnaires provided quantitative scores for anxiety, depression and PTSD. Clients’ personal and physician medical affidavits were analyzed for experiences of violence. Of the 13 cases, anxiety and depression were exhibited by 92 and 100% of women, while all seven women screened for PTSD had symptoms. Qualitative analysis revealed …

Social Work Trauma Interventions: Dialectical Behavioral Therapy, Kassie Baumann

Senior Honors Theses

According to Lynne Weilart (2013), in her article on the reasons why people seek out therapy, trauma is the number one reason people attend counseling. Many different trauma-informed approaches are designed specifically to address the consequences of trauma and to facilitate healing. Some of these approaches are as follows: Cognitive Behavioral Therapy (CBT); Dialectical Behavioral Therapy (DBT);Mentalization Based Therapy (MBT); Trauma Systems Therapy (TST); Trauma Assessment Pathway (TAP); and Attachment, Self-Regulation, and Competency (ARC) (de Arellano, Danielson, Ko, & Sprauge, 2008). The effectiveness of each trauma intervention will be examined. DBT is one of these trauma interventions that is growing …

Mdma-Assisted Psychotherapy For Posttraumatic Stress Disorder: A Review Of The Literature, Erin Solomon

Student Works

A growing number of people suffer chronic, treatment-resistant posttraumatic stress disorder (PTSD; Amoroso & Workman, 2016; Buoso, Doblin, Farré, Alcázar, & Gómez-Jarabo, 2008; Mithoefer, Wagner, Mithoefer, Jerome, & Doblin, 2011; Oehen, Traber, Widmer, & Schnyder, 2013). The most popular treatments, including exposure therapy, may not be effective for some people (Amoroso & Workman, 2016; Mithoefer et al., 2011). Treatment dropout and suicidality are high among people for whom therapy is minimally effective (Amoroso, 2015; Amoroso & Workman, 2016; Mithoefer et al., 2011; Oehen et al., 2013). Researchers have begun to investigate 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy as a possible treatment for PTSD …

Modified Single Prolonged Stress Reduces Cocaine Self-Administration During Acquisition Regardless Of Rearing Environment, Rebecca S. Hofford, Mark A. Prendergast, Michael T. Bardo

Psychology Faculty Publications

Until recently, there were few rodent models available to study the interaction of post-traumatic stress disorder (PTSD) and drug taking. Like PTSD, single prolonged stress (SPS) produces hypothalamic-pituitary-adrenal (HPA) axis dysfunction and alters psychostimulant self-administration. Other stressors, such as isolation stress, also alter psychostimulant self-administration. However, it is currently unknown if isolation housing combined with SPS can alter the acquisition or maintenance of cocaine self-administration. The current study applied modified SPS (modSPS; two hours restraint immediately followed by cold swim stress) to rats raised in an isolation condition (Iso), enrichment condition (Enr), or standard condition (Std) to measure changes in …

The Long-Term Impact Of Maritime Piracy On Seafarers’ Behavioral Health And Work Decisions, D Conor Seyle, Karina Therese G. Fernandez, Alexander Dimitrevich, Chirag Bahri

Psychology Department Faculty Publications

More than 6000 seafarers have been held hostage by pirates in the last ten years. There is a small but developing body of research showing that these seafarers may face lasting challenges in recovery. However, current studies on this question have been limited by a lack of comparison groups, a lack of statistical power, and other methodological challenges. This study contributes to this body of research through a survey of 101 former hostages and 363 seafarers not known to be exposed to piracy from India, the Philippines, and Ukraine. Using clinically validated scales for tracking lasting impact, this research finds …

Habituation Of Distress And Craving During Treatment As Predictors Of Change In Ptsd Symptoms And Substance Use Severity, Christal L. Badour, Julianne C. Flanagan, Daniel F. Gros, Therese Killeen, Irene Pericot-Valverde, Kristina J. Korte, Nicholas P. Allan, Sudie E. Back

Psychology Faculty Publications

Objective—Increasing evidence supports the efficacy of trauma-focused exposure therapy in the treatment of posttraumatic stress disorder (PTSD) and co-occurring substance use disorders. Little is known, however, about the mechanisms of change in treatment for patients with PTSD and co-occurring substance use disorders. The aim of the present study was to examine whether within- and between-session habituation of distress and substance craving during imaginal exposure relates to treatment outcomes among U.S. military veterans with PTSD and a co-occurring substance use disorder (N = 54).

Method—Veterans received Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure, a manualized …

The Impact Of A Civic Service Program On Biopsychosocial Outcomes Of Post 9/11 U.S. Military Veterans, Monica M. Matthieu, Karen A. Lawrence, Emma Robertson-Blackmore

Social Work Faculty Publications

Volunteering as a health promotion intervention, improves physical health, mental health, and social outcomes particularly in older adults, yet limited research exists for veterans. We conducted a preliminary study to explore whether volunteering impacts a variety of biopsychosocial outcomes, including symptoms of post-traumatic stress disorder (PTSD) and depression, among returning military veterans from Iraq and Afghanistan. A survey enrolling a prospective cohort of United States (U.S.) veterans who served in the military after 11 September 2001 and who participated in a national civic service program was conducted. A total of 346 veterans completed standardized health, mental health, and psychosocial self-report …

Student Perceptions Of Services For Veterans And Military Personnel, Philip Parsons

Mahurin Honors College Capstone Experience/Thesis Projects

Many Veterans are returning from the War on Terror and making their way to universities. Due to the many aspects of war and military life many maybe, or are experiencing some level of mental health issue/s. As more Veterans make this transition, resources may not be available for them to be successful in the classroom (Whitley, Tschudi, & Gieber, 2013). After reviewing the literature, a suitable instrument to measure these variables was not available. The researcher developed a survey and sampled students of one Midwestern public university. The variables included basic demographic questions and perceptions of Veterans and the services …

Suicidal Ideation In Patients Hospitalized For Emergency Medical Treatment Related To Physical Trauma: Effects Of Posttraumatic Stress And Depression, Erin E. Carney

Masters Theses & Specialist Projects

Survivors of physical trauma may be at increased risk for developing suicidal ideation and behavior both during and after their inpatient hospitalization for medical treatment of wounds. It remains to be understood why a population hospitalized for nonpsychiatric reasons may ultimately develop a desire to take their own life. The current study sought to answer this question by hypothesizing that symptoms of posttraumatic stress (PTS) and depression during the recovery period individually mediated the relationship between physical pain and suicidal ideation. Researchers assessed these relationships in 246 patients who were receiving emergency medical treatment for wounds associated with a physically …

Demographic Characteristics And Trauma Symptomology In Juvenile Justice Residents At Echo Glen Children's Center, Britta L. Bergan

Antioch University Dissertations & Theses

Exposure to traumatic and stressful events has become increasingly commonplace and the impact of such experiences has been well documented. Trauma events in childhood have been associated with a number of factors, including maladaptive emotional and behavioral responses, increased vulnerability for exposure to additional traumatic events, and adverse experiences later in life. Juvenile justice youth have been found to have higher rates of trauma exposure, when compared to community samples of same-aged peers. The population of youth residing at Echo Glen Children’s Center, in Snoqualmie, Washington, exhibit unique characteristics for a juvenile justice population, including age (the youngest juvenile offenders …

Research Brief: "Receipt Of Employment Services Among Veterans Health Administration Users With Psychiatric Diagnoses", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study found that about four percent (4.2%) of VHA users with psychiatric diagnoses accessed employment services in a given year. VHA patients with a psychiatric diagnosis of schizophrenia had higher odds of accessing employment services relative to VHA users with other psychiatric diagnoses, including PTSD, depression, and other anxiety disorders. In practice, veterans should be aware that receiving VHA employment services should not affect VA benefits and should discuss their medical and financial benefits with benefits advisors and other appropriate advisors. In policy, Policymakers could consider allocating funds to further study the efficacy and effectiveness of various employment services …

2nd Place Contest Entry: Treatment Of Post-Traumatic Stress Disorder In A Veteran Population: Efficacy Of Complementary And Alternative Medicine Therapies, Brooke D. Snelgrove

Kevin and Tam Ross Undergraduate Research Prize

This is Brooke Snelgrove's submission for the 2014-2015 Kevin and Tam Ross Undergraduate Research Prize, which won second place. She wrote about the treatment of post-traumatic stress disorder (PTSD) among veterans with Complementary and Alternative Medicine therapies. You can read the final essay that came out of her research here.