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Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences

University of Massachusetts Boston

Counseling and School Psychology Faculty Publication Series

2011

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Full-Text Articles in Social and Behavioral Sciences

Antidepressants And Breast And Ovarian Cancer Risk: A Review Of The Literature And Researchers' Financial Associations With Industry, Lisa Cosgrove, Ling Shi, David E. Creasey, Maria Anaya-Mckivergan, Jessica A. Myers, Krista F. Huybrechts Apr 2011

Antidepressants And Breast And Ovarian Cancer Risk: A Review Of The Literature And Researchers' Financial Associations With Industry, Lisa Cosgrove, Ling Shi, David E. Creasey, Maria Anaya-Mckivergan, Jessica A. Myers, Krista F. Huybrechts

Counseling and School Psychology Faculty Publication Series

Background

Antidepressant (AD) use has been purported to increase the risk of breast and ovarian cancer, although both epidemiological and pre-clinical studies have reported mixed results [1]–[6]. Previous studies in a variety of biomedical fields have found that financial ties to drug companies are associated with favorable study conclusions [7].

Methods and Findings

We searched English-language articles in MEDLINE, PsychINFO, the Science Citations Index and the Cochrane Central Register of Controlled Clinical Trials (through November 2010). A total of 61 articles that assessed the relationship between breast and ovarian cancer and AD use and articles that examined the effect of …