Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Social and Behavioral Sciences
Sex-Specific Interaction Between Apoe Genotype And Carbohydrate Intake Affects Plasma Hdl-C Levels: The Strong Heart Family Study, M.J. Mosher, L. A. Lange, B. V. Howard, E. T. Lee, L. G. Best, R. R. Fabsitz, J. W. Maccluer, K. E. North
Sex-Specific Interaction Between Apoe Genotype And Carbohydrate Intake Affects Plasma Hdl-C Levels: The Strong Heart Family Study, M.J. Mosher, L. A. Lange, B. V. Howard, E. T. Lee, L. G. Best, R. R. Fabsitz, J. W. Maccluer, K. E. North
Anthropology Faculty and Staff Publications
Low plasma levels of high-density lipoprotein cholesterol (HDL-C) are identified as a risk factor for cardiovascular disease (CVD). Sexual dimorphism, however, is widely reported in both HDL-C and CVD, with the underlying explanations of these sexual differences not fully understood. HDL-C is a complex trait influenced by both genes and dietary factors. Here we examine evidence for a sex-specific effect of APOE and the macronutrient carbohydrate on HDL-C, triglycerides (TG) and apoprotein A-1 (ApoA-1) in a sample of 326 male and 423 female participants of the Strong Heart Family Study (SHFS). Using general estimating equations in SAS to account for …