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Social and Behavioral Sciences Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Social and Behavioral Sciences
Process Evaluation Of An Innovative Sun Protection Intervention Targeting Adolescents, Sandra C. Jones, Keryn M. Johnson, Donald C. Iverson, Jeffrey Thom
Process Evaluation Of An Innovative Sun Protection Intervention Targeting Adolescents, Sandra C. Jones, Keryn M. Johnson, Donald C. Iverson, Jeffrey Thom
Sandra Jones
The purpose of the current intervention was to target a defined segment of the adolescent population with a sun protection ‘offering’ that positioned sun protection as beneficial and addressed identified barriers (particularly inconvenience and image). A community intervention was conducted in one defined geographic region over the 2009/2010 Summer school holidays. Key elements of the intervention included the distribution of augmented products, promotional materials with a pre-tested impactful message, and partnerships with community and commercial organisations. The intervention was successful in creating interest and attention among adolescents. This paper reports on the process evaluations, focusing on barriers, facilitators and lessons …
The Introduction And Evaluation Of A Warfarin Management Strategy Into Illawarra Residential Aged Care Facilities, Margaret Jordan, Judy Mullan, Victoria Traynor
The Introduction And Evaluation Of A Warfarin Management Strategy Into Illawarra Residential Aged Care Facilities, Margaret Jordan, Judy Mullan, Victoria Traynor
Faculty of Health and Behavioural Sciences - Papers (Archive)
No abstract provided.
Synthesis And Preliminary Evaluation Of Amiloride Analogs As Inhibitors Of The Urokinase-Type Plasminogen Activator (Upa), Hayden Matthews, Marie Ranson, Joel Tyndall, Michael J. Kelso
Synthesis And Preliminary Evaluation Of Amiloride Analogs As Inhibitors Of The Urokinase-Type Plasminogen Activator (Upa), Hayden Matthews, Marie Ranson, Joel Tyndall, Michael J. Kelso
Faculty of Science - Papers (Archive)
A known side-activity of the oral potassium-sparing diuretic drug amiloride is inhibition of the enzyme urokinase-type plasminogen activator (uPA, Ki = 7 mu M), a promising anticancer target. Several studies have demonstrated significant antitumor/metastasis properties for amiloride in animal cancer models and it would appear that these arise, at least in part, through inhibition of uPA. Selective optimization of amiloride’s structure for more potent inhibition of uPA and loss of diuretic effects would thus appear as an attractive strategy towards novel anticancer agents. The following report is a preliminary structure-activity exploration of amiloride analogs as inhibitors of uPA. A …