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Articles 1 - 6 of 6
Full-Text Articles in Social and Behavioral Sciences
Are Parents' Working Patterns Associated With Their Child's Sleep? An Analysis Of Dual-Parent Families In Australia, Christopher A. Magee, Peter Caputi, Don C. Iverson
Are Parents' Working Patterns Associated With Their Child's Sleep? An Analysis Of Dual-Parent Families In Australia, Christopher A. Magee, Peter Caputi, Don C. Iverson
Faculty of Health and Behavioural Sciences - Papers (Archive)
Insufficient sleep in children predicts emotional and behavioral problems, poorer school performance, and health problems. Child sleep durations have declined in recent decades, suggesting a need to identify and understand predictors of short sleep. The present study investigated whether aspects of parental employment (i.e. parental work hours, and non-standard work hours) were associated with sleep in children. Data collected from 2477 children aged 6–7 years as part of the Longitudinal Study of Australian Children were used in this paper. Child sleep duration, bedtimes, and wake times were determined from parent self-report using time-use diaries. Parents completed a survey assessing their …
Activation Of The Damage-Associated Molecular Pattern Receptor P2x7 Induces Interleukin-1b Release From Canine Monocytes, Iman Jalilian, Michelle Peranec, Belinda L. Curtis, Aine Seavers, Mari Spildrejorde, Vanessa Sluyter, Ronald Sluyter
Activation Of The Damage-Associated Molecular Pattern Receptor P2x7 Induces Interleukin-1b Release From Canine Monocytes, Iman Jalilian, Michelle Peranec, Belinda L. Curtis, Aine Seavers, Mari Spildrejorde, Vanessa Sluyter, Ronald Sluyter
Faculty of Science - Papers (Archive)
P2X7, a damage-associated molecular pattern receptor and adenosine 5'-triphosphate (ATP)-gated cation channel, plays an important role in the activation of the NALP3 inflammasome and subsequent release of interleukin (IL)-1β from human monocytes; however its role in monocytes from other species including the dog remains poorly defined. This study investigated the role of P2X7 in canine monocytes, including its role in IL-1β release. A fixed-time flow cytometric assay demonstrated that activation of P2X7 by extracellular ATP induces the uptake of the organic cation, YO-PRO-12+, into peripheral blood monocytes from various dog breeds, a process impaired by the specific P2X7 …
Short And Long Sleep Duration Are Associated With Prevalent Cardiovascular Disease In Australian Adults, Christopher A. Magee, Len Kritharides, John Attia, Patrick Mcelduff, Emily Banks
Short And Long Sleep Duration Are Associated With Prevalent Cardiovascular Disease In Australian Adults, Christopher A. Magee, Len Kritharides, John Attia, Patrick Mcelduff, Emily Banks
Faculty of Health and Behavioural Sciences - Papers (Archive)
A growing number of studies from a range of different countries have observed an association between sleep duration and cardiovascular disease. The objective of this paper was to examine the associations between sleep duration and prevalent cardiovascular disease in a large sample of Australian adults, and identify the sociodemographic and health-related factors moderating these associations. Participants included 218 155 Australian adults aged 45 years and over. The results indicated that 6 h versus 7 h sleep was associated with increased odds of heart disease [odds ratio (OR) = 1.11 (1.06–1.17)], diabetes [OR = 1.15 (1.09–1.22)], stroke [OR = 1.25 (1.14–1.38)] …
Land Management Practices Associated With House Loss In Wildfires, Philip Gibbons, Linda Van Bommel, A Malcolm Gill, Geoffrey J. Cary, Don A. Driscoll, Ross A. Bradstock, Emma Knight, Max A. Moritz, Scott L. Stephens, David B. Lindenmayer
Land Management Practices Associated With House Loss In Wildfires, Philip Gibbons, Linda Van Bommel, A Malcolm Gill, Geoffrey J. Cary, Don A. Driscoll, Ross A. Bradstock, Emma Knight, Max A. Moritz, Scott L. Stephens, David B. Lindenmayer
Faculty of Science - Papers (Archive)
Losses to life and property from unplanned fires (wildfires) are forecast to increase because of population growth in periurban areas and climate change. In response, there have been moves to increase fuel reduction—clearing, prescribed burning, biomass removal and grazing—to afford greater protection to peri-urban communities in fire-prone regions. But how effective are these measures? Severe wildfires in southern Australia in 2009 presented a rare opportunity to address this question empirically. We predicted that modifying several fuels could theoretically reduce house loss by 76%–97%, which would translate to considerably fewer wildfire-related deaths. However, maximum levels of fuel reduction are unlikely to …
Alterations To Melanocortinergic, Gabaergic And Cannabinoid Neurotransmission Associated With Olanzapine-Induced Weight Gain, Katrina Weston-Green, Xu-Feng Huang, Chao Deng
Alterations To Melanocortinergic, Gabaergic And Cannabinoid Neurotransmission Associated With Olanzapine-Induced Weight Gain, Katrina Weston-Green, Xu-Feng Huang, Chao Deng
Faculty of Health and Behavioural Sciences - Papers (Archive)
Background/Aim: Second generation antipsychotics (SGAs) are used to treat schizophrenia but can cause serious metabolic side-effects, such as obesity and diabetes. This study examined the effects of low to high doses of olanzapine on appetite/ metabolic regulatory signals in the hypothalamus and brainstem to elucidate the mechanisms underlying olanzapineinduced obesity. Methodology/Results: Levels of pro-opiomelanocortin (POMC), neuropeptide Y (NPY) and glutamic acid decarboxylase (GAD65, enzyme for GABA synthesis) mRNA expression, and cannabinoid CB1 receptor (CB1R) binding density (using [3H]SR- 141716A) were examined in the arcuate nucleus (Arc) and dorsal vagal complex (DVC) of female Sprague Dawley rats following 0.25, 0.5, 1.0 …
Preeclampsia Is Associated With Compromised Maternal Synthesis Of Long-Chain Polyunsaturated Fatty Acids, Leading To Offspring Deficiency, Vanessa A. Mackay, Shahzya S. Huda, Frances M. Stewart, Kahmeng Tham, Louise A. Mckenna, Iain Martin, Fiona Jordan, E Ann Brown, Leanne Hodson, Ian A. Greer, Barbara J. Meyer, Dilys J. Freeman
Preeclampsia Is Associated With Compromised Maternal Synthesis Of Long-Chain Polyunsaturated Fatty Acids, Leading To Offspring Deficiency, Vanessa A. Mackay, Shahzya S. Huda, Frances M. Stewart, Kahmeng Tham, Louise A. Mckenna, Iain Martin, Fiona Jordan, E Ann Brown, Leanne Hodson, Ian A. Greer, Barbara J. Meyer, Dilys J. Freeman
Faculty of Health and Behavioural Sciences - Papers (Archive)
Obesity and excessive lipolysis are implicated in preeclampsia (PE). Intrauterine growth restriction is associated with low maternal body mass index and decreased lipolysis. Our aim was to assess how maternal and offspring fatty acid metabolism is altered in mothers in the third trimester of pregnancy with PE (n=62) or intrauterine growth restriction (n=23) compared with healthy pregnancies (n=164). Markers of lipid metabolism and erythrocyte fatty acid concentrations were measured. Maternal adipose tissue fatty acid composition and mRNA expression of adipose tissue fatty acid–metabolizing enzymes and placental fatty acid transporters were compared. Mothers with PE had higher plasma triglyceride (21%, P<0.001) and nonesterified fatty acid (50%, P<0.001) concentrations than controls. Concentrations of major n−6 and n−3 long-chain polyunsaturated fatty acids in erythrocytes were 23% to 60% lower (all P<0.005) in PE and intrauterine growth restriction mothers and offspring compared with controls. Subcutaneous adipose tissue −5 and −6 desaturase and very long-chain fatty acid elongase mRNA expression was lower in PE than controls (respectively, mean [SD] control 3.38 [2.96] versus PE 1.83 [1.91], P=0.030; 3.33 [2.25] versus 1.03 [0.96], P<0.001; 0.40 [0.81] versus 0.00 [0.00], P=0.038 expression relative to control gene [square root]). Low maternal and fetal long-chain polyunsaturated fatty acid concentrations in PE may be the result of decreased maternal synthesis.