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Social and Behavioral Sciences Commons

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Full-Text Articles in Social and Behavioral Sciences

Chronic Exercise Modifies Age-Related Telomere Dynamics In A Tissue-Specific Fashion, Andrew T. Ludlow, Sarah Witkowski, Mallory R. Marshall, Jenny Wang, Laila C.J. Lima, Lisa M. Guth, Espen E. Spangenburg, Stephen M. Roth Sep 2012

Chronic Exercise Modifies Age-Related Telomere Dynamics In A Tissue-Specific Fashion, Andrew T. Ludlow, Sarah Witkowski, Mallory R. Marshall, Jenny Wang, Laila C.J. Lima, Lisa M. Guth, Espen E. Spangenburg, Stephen M. Roth

Exercise and Sport Studies: Faculty Publications

We evaluated the impact of long-term exercise on telomere dynamics in wild-derived short telomere mice (CAST/Ei) over 1 year. We observed significant telomere shortening in liver and cardiac tissues in sedentary 1-year-old mice compared with young (8 weeks) baseline mice that were attenuated in exercised 1-year-old animals. In contrast, skeletal muscle exhibited significant telomere shortening in exercise mice compared with sedentary and young mice. Telomerase enzyme activity was increased in skeletal muscle of exercise compared with sedentary animals but was similar in cardiac and liver tissues. We observed significant age-related decreases in expression of telomere-related genes that were attenuated by …


Individuals With Non-Specific Low Back Pain In An Active Episode Demonstrate Temporally Altered Torque Responses And Direction-Specific Enhanced Muscle Activity Following Unexpected Balance Perturbations, Stephanie L. Jones, Juvena R. Hitt, Michael J. Desarno, Sharon M. Henry Sep 2012

Individuals With Non-Specific Low Back Pain In An Active Episode Demonstrate Temporally Altered Torque Responses And Direction-Specific Enhanced Muscle Activity Following Unexpected Balance Perturbations, Stephanie L. Jones, Juvena R. Hitt, Michael J. Desarno, Sharon M. Henry

Exercise and Sport Studies: Faculty Publications

Individuals with a history of non-specific low back pain (LBP) while in a quiescent pain period demonstrate altered automatic postural responses (APRs) characterized by reduced trunk torque contributions and increased co-activation of trunk musculature. However, it is unknown whether these changes preceded or resulted from pain. To further delineate the relationship between cyclic pain recurrence and APRs, we quantified postural responses following multi-directional support surface translations, in individuals with non-specific LBP, following an active pain episode. Sixteen subjects with and 16 without LBP stood on two force plates that were translated unexpectedly in 12 directions. Net joint torques of the …


Individuals With Non-Specific Low Back Pain Use A Trunk Stiffening Strategy To Maintain Upright Posture, Stephanie L. Jones, Sharon M. Henry, Christine C. Raasch, Juvena R. Hitt, Janice Y. Bunn Feb 2012

Individuals With Non-Specific Low Back Pain Use A Trunk Stiffening Strategy To Maintain Upright Posture, Stephanie L. Jones, Sharon M. Henry, Christine C. Raasch, Juvena R. Hitt, Janice Y. Bunn

Exercise and Sport Studies: Faculty Publications

There is increasing evidence that individuals with non-specific low back pain (LBP) have altered movement coordination. However, the relationship of this neuromotor impairment to recurrent pain episodes is unknown. To assess coordination while minimizing the confounding influences of pain we characterized automatic postural responses to multi-directional support surface translations in individuals with a history of LBP who were not in an active episode of their pain. Twenty subjects with and 21 subjects without non-specific LBP stood on a platform that was translated unexpectedly in 12 directions. Net joint torques of the ankles, knees, hips, and trunk in the frontal and …