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Full-Text Articles in Social and Behavioral Sciences
Glucose And Acute Exercise Influence Factors Secreted By Circulating Angiogenic Cells In Vitro, Sarah Witkowski, Gayatri Guhanarayan, Rachel Burgess
Glucose And Acute Exercise Influence Factors Secreted By Circulating Angiogenic Cells In Vitro, Sarah Witkowski, Gayatri Guhanarayan, Rachel Burgess
Exercise and Sport Studies: Faculty Publications
Circulating angiogenic cells (CAC) influence vascular repair through the secretion of proangiogenic factors and cytokines. While CAC are deficient in patients with diabetes and exercise has a beneficial effect on CACs, the impact of these factors on paracrine secretion from CAC is unknown. We aimed to determine whether the in vitro secretion of selected cytokines and nitric oxide (NO) from CAC is influenced by hyperglycemia and acute exercise. Colonyforming unit CAC (CFU-CAC) were cultured from young active men (n = 9, 24 ± 2 years) at rest and after exercise under normal (5 mmol/L) and elevated (15 mmol/L) glucose. Preliminary …
Circulating Angiogenic Cell Population Responses To 10 Days Of Reduced Physical Activity, Gayatri Guhanarayan, Julianne Jablonski, Sarah Witkowski
Circulating Angiogenic Cell Population Responses To 10 Days Of Reduced Physical Activity, Gayatri Guhanarayan, Julianne Jablonski, Sarah Witkowski
Exercise and Sport Studies: Faculty Publications
Circulating angiogenic cells (CACs) are a diverse group that have been identified as predictors of cardiovascular health and are inversely proportional to cardiovascular disease (CVD) outcomes. Inactivity is a growing concern in industrialized nations and is an independent risk factor for CVD. There is limited evidence regarding the impact of reduced physical activity (rPA) on different CAC populations. The purpose of this study was to evaluate the effect of objectively monitored rPA with maintained energy balance on two CAC populations (CFU and CD34+cells), intracellular nitric oxide (NOi), and genes related to NO production in active, healthy men. Participants (age 25 …