Social and Behavioral Sciences Commons^™

Catch Me If You Can: Questionable Modelling Assumptions And Parameter Choices And Their Impact On Drug Reimbursement Decisions, Lina Ghattas

Undergraduate Student Research Internships Conference

The Canadian Agency for Drugs and Technologies in Health (CADTH) is a health technology assessment (HTA) agency. CADTH conducts appraisals on health technologies and makes reimbursement recommendations to Canadian public drug plans to guide their reimbursement decisions. When being considered for reimbursement, drug companies submit pharmacoeconomic reports, which typically include long-term decision models. These models make assumptions and use parameters that may favour one intervention over the other. In this study, we comprehensively review the last year of drug submissions appraised by CADTH, with the aim of identifying, categorizing, and critically reviewing key methodological flaws made by drug companies in …