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Articles 1 - 30 of 587
Full-Text Articles in Social and Behavioral Sciences
Decompression Wave Speed In Co2 Mixtures: Cfd Modelling With The Gerg-2008 Equation Of State, Alhoush Elshahomi, Cheng Lu, Guillaume Michal, Xiong Liu, Ajit R. Godbole, Phillip Venton
Decompression Wave Speed In Co2 Mixtures: Cfd Modelling With The Gerg-2008 Equation Of State, Alhoush Elshahomi, Cheng Lu, Guillaume Michal, Xiong Liu, Ajit R. Godbole, Phillip Venton
Faculty of Engineering and Information Sciences - Papers: Part A
The development of CO2 pipelines for Carbon Capture and Storage (CCS) raises new questions regarding the control of ductile fracture propagation and fracture arrest toughness criteria. The decompression behaviour in the fluid must be determined accurately in order to estimate the proper pipe toughness. However, anthropogenic CO2 may contain impurities that can modify the fluid decompression characteristics quite significantly. To determine the decompression wave speed in CO2 mixtures, the thermodynamic properties of these mixtures must be determined by using an accurate equation of state. In this paper we present a new decompression model developed using the Computational Fluid Dynamics (CFD) …
Ion Radiography As A Tool For Patient Set-Up & Image Guided Particle Therapy: A Monte Carlo Study, Nicolas Depauw, Marta F. Dias, Anatoly B. Rosenfeld, Joao C. Seco
Ion Radiography As A Tool For Patient Set-Up & Image Guided Particle Therapy: A Monte Carlo Study, Nicolas Depauw, Marta F. Dias, Anatoly B. Rosenfeld, Joao C. Seco
Faculty of Engineering and Information Sciences - Papers: Part A
This study investigate the use of ion radiography as a tool for patient set-up and tumor tracking capabilities for image guided particle therapy (IGPT) using Monte Carlo simulations. One pediatric, two lung and one liver cancer patients were considered in this study. For each patient, 230 and 330 MeV proton, and 500 MeV/nucleon carbon ion pencil beams were simulated through their computed tomography (CT) data set using GEANT4.9.0. Energy, position and direction cosines of each particle were recorded in front and behind the patient. Ion radiographs were subsequently reconstructed using a dedicated in-house software. The image quality was assessed by …
Model For Acid-Mediated Tumour Invasion With Chemotherapy Intervention I: Spatially Homogeneous Populations, Andrew Brett Holder, Marianito R. Rodrigo
Model For Acid-Mediated Tumour Invasion With Chemotherapy Intervention I: Spatially Homogeneous Populations, Andrew Brett Holder, Marianito R. Rodrigo
Faculty of Engineering and Information Sciences - Papers: Part B
The acid-mediation hypothesis, that is, the hypothesis that acid produced by tumours, as a result of aerobic glycolysis, provides a mechanism for invasion, has so far been considered as a relatively closed system. The focus has mainly been on the dynamics of the tumour, normal-tissue, acid and possibly some other bodily components, without considering the effect of an external intervention such as a cytotoxic treatment. This article aims to examine the effect that a cytotoxic treatment has on a tumour growing under the acid-mediation hypothesis by using a simple set of ordinary differential equations that consider the interaction between normal-tissue, …
Identity-Based Secure Distributed Data Storage Schemes, Jinguang Han, Willy Susilo, Yi Mu
Identity-Based Secure Distributed Data Storage Schemes, Jinguang Han, Willy Susilo, Yi Mu
Faculty of Engineering and Information Sciences - Papers: Part A
Secure distributed data storage can shift the burden of maintaining a large number of files from the owner to proxy servers. Proxy servers can convert encrypted files for the owner to encrypted files for the receiver without the necessity of knowing the content of the original files. In practice, the original files will be removed by the owner for the sake of space efficiency. Hence, the issues on confidentiality and integrity of the outsourced data must be addressed carefully. In this paper, we propose two identity-based secure distributed data storage (IBSDDS) schemes. Our schemes can capture the following properties: (1) …
Intelligent Approaches To Complex Systems, P K. S Prakash, Nagesh Shukla
Intelligent Approaches To Complex Systems, P K. S Prakash, Nagesh Shukla
Faculty of Engineering and Information Sciences - Papers: Part A
Availability of large amount and variety of information and decision making problems in various complex systems ranging from transportation, supply chain, energy to logistics; have placed the need for the development & successful application of advanced intelligent approaches. It is argued that intelligent approaches such as analytics and optimisation techniques drive smarter decisions, faster actions and optimise outcomes in this era. However, there are no single best analytical or optimisation technique to deal with the challenges in various complex systems. It is due to the fact that a technique/approach may show a better performance for a given problem instance; but, …
Data Scientists As Game Changers In Big Data Environments, Akemi T. Chatfield, Vivian N. Shlemoon, Wilbur Redublado, Faizur Rahman
Data Scientists As Game Changers In Big Data Environments, Akemi T. Chatfield, Vivian N. Shlemoon, Wilbur Redublado, Faizur Rahman
Faculty of Engineering and Information Sciences - Papers: Part A
The potential power of big data to generate insights and create new forms of value in the ways which transform organizations and society has been observed by big data-driven organizations and big data experts. Despite the recent sensational declaration of a data scientist as "the sexiest job of the 21st century", however, there has been the lack of rigorous studies of what a data scientist is, and what job skill requirements this hottest job title may need. In order to address this gap, we systematically examine relevant source material to extract definitions and categorize them with a classification scheme developed …
Roles Of Social Media In Open Data Environments: A Case Study Of The 2014 Indonesian Presidential Election Voting Results, Uuf Brajawidagda, Akemi T. Chatfield
Roles Of Social Media In Open Data Environments: A Case Study Of The 2014 Indonesian Presidential Election Voting Results, Uuf Brajawidagda, Akemi T. Chatfield
Faculty of Engineering and Information Sciences - Papers: Part A
Open data initiatives are critical to open government policies which promote transparency, citizen engagement and collaboration. However, they face challenges in realizing their potential benefits through citizens' active engagement. Despite the sharp rise of social media use by governments or quasi-governmental organizations to engage citizens in transforming public service quality and offers, very little has been written on enabling roles of social media in influencing the outcome of open data initiatives. This research examines the potential enabling roles of social media in motivating and having citizens' engagement easier in open data environments. Specifically, we present social media use in supporting …
Beyond The Game: Issues With Social Media And Sporting Events, Matthew Halliwell, Mark Freeman
Beyond The Game: Issues With Social Media And Sporting Events, Matthew Halliwell, Mark Freeman
Faculty of Engineering and Information Sciences - Papers: Part A
Society today is being transformed through the use of Social Media. While the resulting changes are typically marketed as having positive benefits on society, there is a negative side to Social Networking platform usage. This paper considers the case of Social Networking use for a perceived sports betting incident at the Super Bowl XLVIII with boxer Floyd Mayweather, to demonstrate the modified experience some users faced during the sporting event as a result of Social Media. Analysis of the broadcast of negative sentiments associated with inappropriate use and misinformation demonstrates how Social Networking allows opinions and ideas to be spread …
Whole-Genome Analysis Of Multienvironment Or Multitrait Qtl In Magic, Arunas P. Verbyla, Colin R. Cavanagh, Klara L. Verbyla
Whole-Genome Analysis Of Multienvironment Or Multitrait Qtl In Magic, Arunas P. Verbyla, Colin R. Cavanagh, Klara L. Verbyla
Faculty of Engineering and Information Sciences - Papers: Part A
Multiparent Advanced Generation Inter-Cross (MAGIC) populations are now being utilized to more accurately identify the underlying genetic basis of quantitative traits through quantitative trait loci (QTL) analyses and subsequent gene discovery. The expanded genetic diversity present in such populations and the amplified number of recombination events mean that QTL can be identified at a higher resolution. Most QTL analyses are conducted separately for each trait within a single environment. Separate analysis does not take advantage of the underlying correlation structure found in multienvironment or multitrait data. By using this information in a joint analysis-be it multienvironment or multitrait - it …
The Relationship Between The Quality Of Active Frontages And Public Perceptions Of Public Spaces, Emma Elizabeth Heffernan, Troy W. Heffernan, Wei Pan
The Relationship Between The Quality Of Active Frontages And Public Perceptions Of Public Spaces, Emma Elizabeth Heffernan, Troy W. Heffernan, Wei Pan
Faculty of Engineering and Information Sciences - Papers: Part A
Active frontages are often advocated in best practice guidance and by local planning authorities. However, little research has been carried out to establish what benefits, if any, active frontages offer. Previous research in this area has been limited to examining observed behaviour rather than analysing public perceptions. This article aims to improve the understanding of the relationship between the quality of an active frontage and public perceptions of the public space the frontage addresses. The research was carried out through a combination of a critical literature review and a questionnaire survey that engaged 152 participants. The participants' perceptions of a …
Higher Order Or Fractional Order Hardy-Sobolev Type Equations, Wenxiong Chen, Yanqin Fang
Higher Order Or Fractional Order Hardy-Sobolev Type Equations, Wenxiong Chen, Yanqin Fang
Faculty of Engineering and Information Sciences - Papers: Part A
In this paper we consider the following higher order or fractional order Hardy-Sobolev type equation.
An Architecture Framework Modification Supporting The Acquisition Stakeholders, Farid Shirvani, Mahmoud Efatmaneshnik, Allan P. Campbell
An Architecture Framework Modification Supporting The Acquisition Stakeholders, Farid Shirvani, Mahmoud Efatmaneshnik, Allan P. Campbell
Faculty of Engineering and Information Sciences - Papers: Part A
Architectural modeling is gaining support for urban system development to help governments, local agencies and large enterprises acquire, maintain and develop complex infrastructure. This paper proposes a modification to TRAK (The Rail Architecture frameworK) to make it more suitable for acquisition of the general class of urban infrastructure systems. In this paper four of the main system stakeholders, namely acquirer, developer, investor and regulator are chosen and their concerns are identified. In order to identify the gaps, the procurement viewpoints of TRAK are investigated and analyzed to show their inefficiencies in expressing acquisition scenarios and addressing the concerns of those …
Influence Of The Nonlinear Gain On The Stability Limit Of A Semiconductor Laser With Optical Feedback, Yuanlong Fan, Yanguang Yu, Jiangtao Xi, Huiying Ye
Influence Of The Nonlinear Gain On The Stability Limit Of A Semiconductor Laser With Optical Feedback, Yuanlong Fan, Yanguang Yu, Jiangtao Xi, Huiying Ye
Faculty of Engineering and Information Sciences - Papers: Part A
This paper presents the results revealing the influence of the nonlinear gain on the stability limit of a semiconductor laser (SL) with external optical feedback (EOF). A new system determinant is derived from the original Lang and Kobayashi (L-K) equations. By making analysis on the locus of the roots of the system determinant, the stability limit of the system is obtained, from which a number of important and interesting phenomenon revealed by the nonlinear gain is uncovered. The correctness of results is verified by numerical simulations.
Crowd Behavior Recognition Using Dense Trajectories, Muhammad Rizwan Khokher, Abdesselam Bouzerdoum, Son Lam Phung
Crowd Behavior Recognition Using Dense Trajectories, Muhammad Rizwan Khokher, Abdesselam Bouzerdoum, Son Lam Phung
Faculty of Engineering and Information Sciences - Papers: Part A
This article presents a new method for crowd behavior recognition, using dynamic features extracted from dense trajectories. The histogram of oriented gradient and motion boundary histogram descriptors are computed at dense points along motion trajectories, and tracked using median filtering and displacement information obtained from a dense optical flow field. Then a global representation of the scene is obtained using a bag-of-words model of the extracted features. The locality-constrained linear encoding with sum pooling and L2 plus power normalization are employed in the bag-of-words model. Finally, a support vector machine classifier is trained to recognize the crowd behavior in a …
Quality Of Experience-Based Image Feature Selection For Mobile Augmented Reality Applications, Yi Cao, Christian H. Ritz, Raad Raad
Quality Of Experience-Based Image Feature Selection For Mobile Augmented Reality Applications, Yi Cao, Christian H. Ritz, Raad Raad
Faculty of Engineering and Information Sciences - Papers: Part A
Mobile augmented reality applications rely on automatically recognising a visual scene through matching of derived image features. To ensure the Quality of Experience (QoE) perceived by users, such applications should achieve high matching accuracy meanwhile minimizing the waiting time to meet real-time requirement. An efficient solution is to develop an effective feature selection method to select the most robust features against distortions caused by camera capture to achieve high matching accuracy whilst transmission and matching process of the features are significant reduced. Feature selection is also beneficial to reducing the computational complexities of the matching system so that waiting time …
Balancing Energy In The Smart Grid Using Distributed Value Function (Dvf), Hassan Shirzeh, Fazel Naghdy, Philip Ciufo, Montserrat Ros
Balancing Energy In The Smart Grid Using Distributed Value Function (Dvf), Hassan Shirzeh, Fazel Naghdy, Philip Ciufo, Montserrat Ros
Faculty of Engineering and Information Sciences - Papers: Part A
As the penetration of renewable energy resources increases in distribution networks, so does the need to manage these resources in an effective manner. Since these resources are installed to displace carbon-based generation and to provide an income stream to the resource owner, it is important that both installation objectives (as a minimum) can be met. With all of these renewable energy resources available, the opportunity also exists to assist with the energy management of this resource-rich distribution network. However, the renewable energy resources do not produce power in a deterministic manner. The available production depends on the time of day …
Response Of The Al Σ5 〈001〉 Left {310} Symmetric Tilt Grain Boundary To The Shear Deformation Simulated By Molecular Dynamics, Kuiyu Cheng, Cheng Lu, A Kiet Tieu
Response Of The Al Σ5 〈001〉 Left {310} Symmetric Tilt Grain Boundary To The Shear Deformation Simulated By Molecular Dynamics, Kuiyu Cheng, Cheng Lu, A Kiet Tieu
Faculty of Engineering and Information Sciences - Papers: Part A
In the present study, shear response of the Al [001] symmetrical tilting Σ5 (310) grain boundary (GB) was investigated by a three dimensional bicrystal at 500~750 K. It was found that the GB gradually rotated around the [001] tilt axis during the shear deformation due to the combination of surface strain, GB sliding and GB coupled motion. These rotated grain boundaries were Σ5 asymmetrical or symmetrical tilt grain boundaries and led to the normal stress σxx in the bicrystal system. It was also found that the response of the grain boundary to the shear deformation was closely related to the …
Vacancy-Type Defects Study On Ultra-Fine Grained Aluminium Processed By Severe Plastic Deformation, Li-Jun Su, C Lu, Guanyu Deng, A Kiet Tieu, L C. Zhang, P Guagliardo, S N. Samarin, J F. Williams
Vacancy-Type Defects Study On Ultra-Fine Grained Aluminium Processed By Severe Plastic Deformation, Li-Jun Su, C Lu, Guanyu Deng, A Kiet Tieu, L C. Zhang, P Guagliardo, S N. Samarin, J F. Williams
Faculty of Engineering and Information Sciences - Papers: Part A
Vacancy-type defects play an important role in the metal materials deformed by severe plastic deformation (SPD). The present work use positron annihilation lifetime spectroscopy (PALS) to test the vacancy-type defects in aluminium alloys processed by equal channel angular pressing (ECAP) and accumulative roll bonding (ARB). ECAP at room temperature and cryogenic temperature was conducted to AA1050 and ARB with 200 C preheating was conducted to AA1050 and AA6061 to produce laminated AA1050 sheets, AA6061 sheets and AA1050/AA6061 composites. High fraction of vacancy-type defects were detected in all the deformed samples. Vacancies associated with dislocations and bulk mono-vacancies have been identified …
A Round-Robin Test With Thermal Simulation Of The Welding Haz To Draw Cct Diagrams: A Need For Harmonized Procedures And Microconstituent Terminologies, Americo Scotti, Huijun Li, Rosa M. Miranda
A Round-Robin Test With Thermal Simulation Of The Welding Haz To Draw Cct Diagrams: A Need For Harmonized Procedures And Microconstituent Terminologies, Americo Scotti, Huijun Li, Rosa M. Miranda
Faculty of Engineering and Information Sciences - Papers: Part A
Thermal simulations of heat affected zone (HAZ) have been widely used. This is an economic expedite process for phase transformation evaluations in steels when subjected to weld thermal cycles as well as to draw continuous cooling transformation (CCT) diagrams. Different approaches for the simulation and parameter settings have been used by several researchers, yet leading to not always even results. Thus, it was proposed a round-robin test trial performed by different laboratories, aiming to evidence potential sources of error or inadequacy of the approaches. A High Strength Low Alloy (HSLA) steel was used as a case study. Despite the limited …
Formability Of Micro Sheet Hydroforming Of Ultra-Fine Grained Stainless Steel, Hideki Sato, Kenichi Manabe, Daiki Kondo, Dongbin Wei, Zhengyi Jiang
Formability Of Micro Sheet Hydroforming Of Ultra-Fine Grained Stainless Steel, Hideki Sato, Kenichi Manabe, Daiki Kondo, Dongbin Wei, Zhengyi Jiang
Faculty of Engineering and Information Sciences - Papers: Part A
The formability of ultra-fine grained stainless steel is investigated in micro hydromechanical deep drawing. The materials used are ultra-fine grained stainless steel and SUS304-H with thickness of 20 and 50 m. The micro cups are successfully fabricated for the ultra-fine grained stainless steel but it cannot be fabricated for SUS304-H with thickness of 20 μm. The fracture type of ultra-fine grained stainless steel foil is the shortage of tensile strength at plain strain state and does not change with a decrease of the thickness. In contrast, the fracture type of SUS304-H foil changes to the bending deformation with decreasing the …
Numerical Study On Springback With Size Effect In Micro V-Bending, Zhi Fang, Haina Lu, Dongbin Wei, Zhengyi Jiang, Xianming Zhao, Di Wu
Numerical Study On Springback With Size Effect In Micro V-Bending, Zhi Fang, Haina Lu, Dongbin Wei, Zhengyi Jiang, Xianming Zhao, Di Wu
Faculty of Engineering and Information Sciences - Papers: Part A
With the development of microforming technology, the demand on accuracy of the metallic micro components is elevating. While springback phenomenon which is inevitable during bending process, can cause unpredicted dimensional error, bringing difficulties to the downstream assembly, and let alone the springback in microforming as the measurements of tools and workpieces downsize hundreds even thousands times. This paper focuses on the springback effect that occurs after the micro Vbending a classic processing method to manufacture microparts. Numerical simulation has been conducted to investigate the size effect in terms of Voronoi tessellation and springback. A finite element (FE) model of the …
Development Of High Melting Temperature Microencapsulated Phase Change Material For Compacted Thermal Energy Storage Bed, Weiguang Su, Jo Darkwa, Georgios Kokogiannakis
Development Of High Melting Temperature Microencapsulated Phase Change Material For Compacted Thermal Energy Storage Bed, Weiguang Su, Jo Darkwa, Georgios Kokogiannakis
Faculty of Engineering and Information Sciences - Papers: Part A
In this paper a novel high temperature microencapsulated phase change material (MEPCM) based on paraffin as the core material and MF resin as the shell material has been developed with the in-situ polymerization method for solar hot water storage application. The results showed that the type of emulsifier could influence core material content, the encapsulation efficiency as well as the latent heat capacity. Based on the results and analysis the study has shown that energy storage density could be increased by as much as 59% if 60wt% of MEPCM 1 was to be used in the proposed compacted MEPCM-water bed …
Mathematical Modeling And Experimental Verification Of Fluid Flow Through Deformable Rough Rock Joints, Buddhima Indraratna, Chandrasiri Kumara, Song-Ping Zhu, Scott Sloan
Mathematical Modeling And Experimental Verification Of Fluid Flow Through Deformable Rough Rock Joints, Buddhima Indraratna, Chandrasiri Kumara, Song-Ping Zhu, Scott Sloan
Faculty of Engineering and Information Sciences - Papers: Part A
Rock joints exert an enormous influence on the permeability of a rock mass because they act as interconnecting networks that provide pathways for fluids to permeate and flow within the rock structure. The apertures in rock joints are irregular in nature and induce flows that cannot be described by the parallel-plate theory based on planar joints or the classical cubic flow relationships. In this study, a two-dimensional (2D) hydraulic aperture distribution was considered to develop a mathematical model for fracture flow. In this approach, the three-dimensional Navier-Stokes equation was integrated over the joint aperture and converted to an equivalent 2D …
Soil Distrubance Associated With Mandrel-Driven Prefabricated Vertical Drains: Field Experience, Darshana Perera, Buddhima Indraratna, Cholachat Rujikiatkamjorn
Soil Distrubance Associated With Mandrel-Driven Prefabricated Vertical Drains: Field Experience, Darshana Perera, Buddhima Indraratna, Cholachat Rujikiatkamjorn
Faculty of Engineering and Information Sciences - Papers: Part A
It has been widely known that load-settlement behaviors of cast-in placed bored piles are determined not only by the soil properties alone but also by the construction methods. This paper discusses the performances of (6) instrumented test piles of various diameters (80; 100 and 120 cm) and constructed using different techniques i.e. mud-water, polymer slurry and full-casing under relatively uniform subsurface condition that consisting of very stiff silty clay in West Jakarta. Each test pile was instrumented by vibrating wire strain gauge (VWSGs) and loaded to near ultimate load ( 2.5 times design load) with objective to obtain the loadtransfer …
Experimental Study On The Effectiveness Of Cfrp Strengthening Of Shear-Deficient Reinforced Concrete Beams Under Impact Loading, M W. Goldston, A M. Remennikov, M N. Sheikh
Experimental Study On The Effectiveness Of Cfrp Strengthening Of Shear-Deficient Reinforced Concrete Beams Under Impact Loading, M W. Goldston, A M. Remennikov, M N. Sheikh
Faculty of Engineering and Information Sciences - Papers: Part A
The paper focuses on understanding the importance of shear mechanisms on reinforced concrete (RC) beams and comparing with CFRP externally reinforced beams under static and impact loading. A total of six RC beams were tested in two groups: shear-deficient (A) and externally reinforced beams (B) with carbon fibre reinforced polymer (CFRP). All beams designed had identical reinforcement properties with the intent to investigate the influences of composite materials on the overall results. Emphasis was placed on crack propagation, experimental failure modes and prevention methods. Experimental results confirm that increases in the shear reinforcement decreases the overall impact displacement, indicating that …
18f-Fmiso Pet/Ct Visualization Of Tumor Hypoxia In Patients With Chordoma Of The Mobile And Sacrococcygeal Spine, Matthew D. Cheney, Yen-Lin Chen, Ruth Lim, Barbara K. Winrich, Anca L. Grosu, Alexei V. Trofimov, Nicolas Depauw, Helen A. Shih, Joseph H. Schwab, Francis J. Hornicek, Thomas F. Delaney
18f-Fmiso Pet/Ct Visualization Of Tumor Hypoxia In Patients With Chordoma Of The Mobile And Sacrococcygeal Spine, Matthew D. Cheney, Yen-Lin Chen, Ruth Lim, Barbara K. Winrich, Anca L. Grosu, Alexei V. Trofimov, Nicolas Depauw, Helen A. Shih, Joseph H. Schwab, Francis J. Hornicek, Thomas F. Delaney
Faculty of Engineering and Information Sciences - Papers: Part A
Abstract presented at the American Society for Radiation Oncology 56th Annual Meeting, ASTRO's 56th Annual Meeting, San Francisco, United States, 14–17 September 2014
High-Performance Binary Blazed Grating Coupler Used In Silicon-Based Hybrid Photodetector Integration, Hongqiang Li, Yu Liu, Chunjiao Miao, Meiling Zhang, Wenqian Zhou, Chunxiao Tang, Enbang Li
High-Performance Binary Blazed Grating Coupler Used In Silicon-Based Hybrid Photodetector Integration, Hongqiang Li, Yu Liu, Chunjiao Miao, Meiling Zhang, Wenqian Zhou, Chunxiao Tang, Enbang Li
Faculty of Engineering and Information Sciences - Papers: Part A
An efficient and high-performance binary blazed grating coupler was designed based on silicon-on-insulator (SOI) used for silicon-based hybrid photodetector integration in an arrayed waveguide grating demodulation integrated microsystem. A relatively high coupling efficiency was obtained to optimize mode matching by the finite-difference time-domain method by choosing appropriate grating parameters, including period, etching depth, and fill factor. Coupling efficiency output at 1550 nm for the TE mode reached 68%. This value was >60% in the wavelength range of 1450 to 1600 nm, specifically 71.4% around 1478 nm. An InP/InGaAs photodetector and SOI wafer were integrated by using benzocyclobutene (BCB) bonding. When …
Positron Emission Tomography And Functional Characterization Of A Complete Pbr/Tspo Knockout, Richard B. Banati, Ryan J. Middleton, Ronald Chan, Claire R. Hatty, Winnie Wai-Ying Kam, Candice Quin, Manuel B. Graeber, Arvind Parmar, David Zahra, Paul Callaghan, Sandra Fok, Nicholas R. Howell, Marie Gregoire, Alexander Szabo, Tien Pham, Emma Davis, Guo-Jun Liu
Positron Emission Tomography And Functional Characterization Of A Complete Pbr/Tspo Knockout, Richard B. Banati, Ryan J. Middleton, Ronald Chan, Claire R. Hatty, Winnie Wai-Ying Kam, Candice Quin, Manuel B. Graeber, Arvind Parmar, David Zahra, Paul Callaghan, Sandra Fok, Nicholas R. Howell, Marie Gregoire, Alexander Szabo, Tien Pham, Emma Davis, Guo-Jun Liu
Faculty of Engineering and Information Sciences - Papers: Part A
The evolutionarily conserved peripheral benzodiazepine receptor (PBR), or 18-kDa translocator protein (TSPO), is thought to be essential for cholesterol transport and steroidogenesis, and thus life. TSPO has been proposed as a biomarker of neuroinflammation and a new drug target in neurological diseases ranging from Alzheimer’s disease to anxiety. Here we show that global C57BL/6-Tspotm1GuWu(GuwiyangWurra)-knockout mice are viable with normal growth, lifespan, cholesterol transport, blood pregnenolone concentration, protoporphyrin IX metabolism, fertility and behaviour. However, while the activation of microglia after neuronal injury appears to be unimpaired, microglia from GuwiyangWurraTSPO knockouts produce significantly less ATP, suggesting reduced metabolic activity. Using the isoquinoline …
Topologically Guaranteed Enhancement Of Nonlinear Optical Conductivity Of Graphene In The Presence Of Spin-Orbit Coupling, Zheng Liu, Matthew Sanderson, J C. Cao, C Zhang
Topologically Guaranteed Enhancement Of Nonlinear Optical Conductivity Of Graphene In The Presence Of Spin-Orbit Coupling, Zheng Liu, Matthew Sanderson, J C. Cao, C Zhang
Faculty of Engineering and Information Sciences - Papers: Part A
We demonstrate that a topological invariant term in graphene (e.g., spin-orbit coupling or interlayer coupling induced trigonal warping) can lead to a strong nonlinear optical response. We present a full quantum-mechanical analysis of the third-order nonlinear optical conductivity of the monolayer graphene with a finite Rashba spin-orbit coupling. For energy of the incident photon below the maximum height of the trigonal warping and the Rashba coupling strength exceeding a critical value the nonlinear conductance is enhanced dramatically in comparison with that in the absence of the topological term. Due to the trigonal warping effect and the topologically inequivalent change of …
Rejection Of Small Solutes By Reverse Osmosis Membranes For Water Reuse Applications: A Pilot-Scale Study, Takahiro Fujioka, Kha L. Tu, Stuart J. Khan, James A. Mcdonald, Annalie Roux, Yvan Poussade, Jörg E. Drewes, Long D. Nghiem
Rejection Of Small Solutes By Reverse Osmosis Membranes For Water Reuse Applications: A Pilot-Scale Study, Takahiro Fujioka, Kha L. Tu, Stuart J. Khan, James A. Mcdonald, Annalie Roux, Yvan Poussade, Jörg E. Drewes, Long D. Nghiem
Faculty of Engineering and Information Sciences - Papers: Part A
N-nitrosamines and boron are small solutes of particular concern during water recycling applications. Here, we evaluated the rejection of seven N-nitrosamines and boron under a range of operating conditions and feed solution characteristics. The evaluationwas conducted using a pilot-scale reverse osmosis (RO) system to appropriately simulate hydrodynamic conditions of full-scale RO installations. The rejection of seven N-nitrosamines by the pilot RO system varied significantly in the range from 31 to 94%, and rejection increased in the increasing order of their molecular weight. Rejection values obtained from this pilot-scale study were lower than those previously reported in laboratory-scale studies. These discrepancieswere …