Social and Behavioral Sciences Commons^™

Impact Of Home Visit Capacity On Genetic Association Studies Of Late-Onset Alzheimer's Disease, David W. Fardo, Laura E. Gibbons, Shubhabrata Mukherjee, M. Maria Glymour, Wayne Mccormick, Susan M. Mccurry, James D. Bowen, Eric B. Larson, Paul K. Crane

Biostatistics Faculty Publications

INTRODUCTION—Findings for genetic correlates of late-onset Alzheimer's disease (LOAD) in studies that rely solely on clinic visits may differ from those with capacity to follow participants unable to attend clinic visits.

METHODS—We evaluated previously identified LOAD-risk single nucleotide variants in the prospective Adult Changes in Thought study, comparing hazard ratios (HRs) estimated using the full data set of both in-home and clinic visits (n = 1697) to HRs estimated using only data that were obtained from clinic visits (n = 1308). Models were adjusted for age, sex, principal components to account for ancestry, and additional health indicators.

RESULTS …

Commentary: "How Much Is That Player In The Window? The One With The Early Birthday?" Relative Age Influences The Value Of The Best Soccer Players, But Not The Best Businesspeople, Luca Fumarco, Benjamin G. Gibbs

Faculty Publications

Fuelled by Gladwell's (2008), researchers have expanded their gaze beyond sports for evidence of the Relative Age Effect: that something as arbitrary as the month you were born in has important consequence for later life success. In line with Furley et al. (2016), we agree that any RAE outside of sports deserves closer scrutiny, but unlike Furley et al., we argue that we should not expect to find evidence of RAE for labor market outcomes in the first place, because there is not sufficient evidence of uniform age cut-offs in school.