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Full-Text Articles in Social and Behavioral Sciences

Sucrose Demand And Essential Value In Mice With Early-Life Exposure To Risperidone, Megan Federoff May 2023

Sucrose Demand And Essential Value In Mice With Early-Life Exposure To Risperidone, Megan Federoff

LSU Master's Theses

Second-generation antipsychotics (SGAs), such as risperidone, are widely prescribed to children, but the long-term effects of SGA treatment are not well understood. This study investigated the impact of early-life risperidone treatment on sucrose demand in mice in adulthood. Mice were administered risperidone or vehicle from postnatal day (PND) 33 to 60 and trained in adulthood (>PND 120) to nose poke for a sucrose solution reinforcer. The fixed ratio (FR) value (the number of responses required to produce sucrose delivery; the “price” of sucrose) was varied from 1 to 45, and the resulting consumption versus FR value data were analyzed …


Examining The Repeatable Battery For The Assessment Of Neuropsychological Status Validity Indices In People With Schizophrenia Spectrum Disorders, Rune Raudeberg, Justin E. Karr, Grant L. Iverson, Åsa Hammar Feb 2021

Examining The Repeatable Battery For The Assessment Of Neuropsychological Status Validity Indices In People With Schizophrenia Spectrum Disorders, Rune Raudeberg, Justin E. Karr, Grant L. Iverson, Åsa Hammar

Psychology Faculty Publications

Objective: We examined the frequency of possible invalid test scores on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in patients with schizophrenia spectrum disorders, and whether there was an association between scores on the embedded RBANS performance validity tests (PVTs) and self-reported symptoms of apathy as measured by the Initiate Scale of the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A). Methods: Participants included 250 patients (M = 24.4 years-old, SD = 5.7) with schizophrenia spectrum disorders. Base rates of RBANS Effort Index (EI), Effort Scale (ES), and Performance Validity Index (PVI) test scores were computed. …


Face Affect Perception In Schizophrenia And Posttraumatic Stress Disorder, Lisa Beckman May 2019

Face Affect Perception In Schizophrenia And Posttraumatic Stress Disorder, Lisa Beckman

UNLV Theses, Dissertations, Professional Papers, and Capstones

Schizophrenia (SZ) and Posttraumatic Stress Disorder (PTSD) are often comorbid psychological disorders. Separately, research has previously demonstrated deficits in social cognition, including affect recognition impairment in both disorders; however, less is reliably known about the specific deficits unique to a comorbid diagnosis of SZ and PTSD. This study examined the ability to correctly identify facial expressions in individuals diagnosed with SZ (n = 38) and PTSD alone (n = 20), comorbid SZ and PTSD (n = 26), and healthy controls (n = 28). Participants were administered a test battery to establish diagnoses of of schizophrenia and PTSD, and to evaluate …


Impact Of Self-Determined Motivation On Work Behavior And Response To Cognitive Remediation In Individuals With Schizophrenia, Desmond Spann Jan 2019

Impact Of Self-Determined Motivation On Work Behavior And Response To Cognitive Remediation In Individuals With Schizophrenia, Desmond Spann

All Graduate Theses, Dissertations, and Other Capstone Projects

Research has implicated motivational deficits as having a severe impact on functional outcomes and quality of life for individuals with schizophrenia. There has been a call for investigation on how these motivational deficits impact different aspects of the therapeutic process for these individuals. A popular model of motivation used in recent investigation with schizophrenia has been Self-Determination Theory. This theory tries to describe why individuals undertake specific goals and behaviors, with the focus being the content of goal-directed outcomes and the regulatory processes with which outcomes are pursued. The goal of this investigation is to examine the impact of self-determined …


Examining Attentional Control And Processing Speed Deficits As Underlying Mechanisms Of Neuropsychological Impairment In Schizophrenia, Mayte Forte Dec 2017

Examining Attentional Control And Processing Speed Deficits As Underlying Mechanisms Of Neuropsychological Impairment In Schizophrenia, Mayte Forte

Graduate Masters Theses

Neuropsychological impairment is a key characteristic of schizophrenia (SZ), but its cognitive profile and underlying information processing mechanisms are not yet well understood. We compare patterns of neuropsychological functioning in 85 persons with SZ and 76 healthy controls across measures of intelligence, memory, and executive function. We then test the hypothesis that neuropsychological impairment in SZ is related to dual deficits in two related but distinct information processes: processing speed and attentional control. All research participants completed Wechsler Adult Intelligence Scale-Third Edition (WAIS-III), Wechsler Memory Scale Third Edition (WMS-III), and Wisconsin Card Sorting Test (WCST), all of which provided measures …


Comparison Of Implicit Thought And Learning In Individuals With Schizophrenia, Camilla Seippel Jun 2017

Comparison Of Implicit Thought And Learning In Individuals With Schizophrenia, Camilla Seippel

Antioch University Full-Text Dissertations & Theses

This investigation studied implicit learning differences in individuals with schizophrenia. Three implicit learning strategies were examined: priming, procedural, and incidental learning. Twenty-six participants with schizophrenia were recruited from various outpatient clinics and programs in Orange, CA to participate in this study. Participants were administered a psychological battery composed of tests to measure individual differences in implicit learning abilities within the group. Differences in crystallized and fluid knowledge abilities within the different implicit learning conditions were tested. Demographic information was also collected and where possible included for the purpose of accounting for demographic variations amongst participants. Demographic variables included the participant’s …


Breaking Apart The Reinforcement Learning Deficit In Schizophrenia, Adam Culbreth Aug 2015

Breaking Apart The Reinforcement Learning Deficit In Schizophrenia, Adam Culbreth

Arts & Sciences Electronic Theses and Dissertations

Reinforcement learning deficits have long been associated with schizophrenia. However, tasks traditionally used to assess these deficits often rely on multiple processing streams leaving the etiology of these task deficits unclear. In the current study, we borrowed a recent framework from computational neuroscience, which separates reinforcement-learning into two distinct systems, model-based and model-free. Under this framework, the model-free system learns about the value of actions in the immediate context, while the model-based system learns about the value of actions in both immediate and subsequent states that may be encountered as a result of their actions. Using a decision task that …


Electrophysiological Changes In P200 Latency And Amplitude Of Jittered Orientation Visual Integration Task In Healthy Participants: A Multi-Block Design Eeg Study, Monika M. Rozynski, Chi-Ming Chen Apr 2015

Electrophysiological Changes In P200 Latency And Amplitude Of Jittered Orientation Visual Integration Task In Healthy Participants: A Multi-Block Design Eeg Study, Monika M. Rozynski, Chi-Ming Chen

Honors Scholar Theses

Visual integration, the ability to fuse environmental information such as light, color, shades, and motion to form a representation of a whole cohesive higher-order visual image, is impaired in persons with schizophrenia. Little is known how the P200 component, an event-related potential (ERP) in the parieto-occipital region, is affected in persons with schizophrenia while they perform visual integration tasks, when compared to healthy persons. This study administered Gabor contours that varied in high and low degrees of orientational jitter through the Jitter Orientation Visual Integration (JOVI) task to investigate visual integration by analyzing latency and amplitude of the P200 component. …


Electrophysiological Changes Of N100 Latency And Amplitude In Healthy Participants Performing The Jitter Orientated Visual Integration Task: A Multi-Block Design Study, Fariya Naz Apr 2015

Electrophysiological Changes Of N100 Latency And Amplitude In Healthy Participants Performing The Jitter Orientated Visual Integration Task: A Multi-Block Design Study, Fariya Naz

University Scholar Projects

The present study investigated the differences in processing during visual integration in healthy adults. The visual N100 indexes early visual discrimination and in this case, was hypothesized to show differences in both latency and amplitude depending on the level of difficulty which corresponds to orientational jitter in a visual integration task. Four blocks with pseudo-random levels of jitter were presented to participants in the Jitter Oriented Visual Integration (JOVI) task. Results looking at the Oz channel showed significant reduction in amplitude in the visual N100 during the more difficult levels condition of the task. The multi-block design, originally expected to …


Impaired Theory Of Mind In Psychotic And Affective Disorders, Erik Nelson Ringdahl Aug 2014

Impaired Theory Of Mind In Psychotic And Affective Disorders, Erik Nelson Ringdahl

UNLV Theses, Dissertations, Professional Papers, and Capstones

Psychotic symptoms in bipolar I disorder during mood episodes has been associated with several negative outcomes raising the question as to whether psychosis is a risk factor for a more severe form of this chronic and debilitating condition. However, relatively little research has been directed at understanding the relationships among social cognitive functioning in bipolar I disorder with and without a history of psychosis. Impaired social cognition has been identified as a putative endophenotypic markers in schizophrenia and the evidence is mounting as to whether similar impairments also exist in bipolar I disorder. Given the plethora of research supporting the …


The Schizophrenias, Robert Carson, Charles Sanislow Dec 1993

The Schizophrenias, Robert Carson, Charles Sanislow

Charles A. Sanislow

No abstract provided.