Social and Behavioral Sciences Commons^™

Validation Of The Adapted Cogstate Brief Battery In Hematopoietic Cell Transplant Patients, Bethany Gourley

Master's Theses and Doctoral Dissertations

A small literature has documented cognitive deficits in adult hematopoietic cell transplant (HCT) survivors across the transplant trajectory, primarily occurring in memory, executive function, attention, and processing speed. Although HCT-associated cognitive decline occurring within one year of transplantation is well documented, only two studies have longitudinally investigated cognitive function in HCT survivors beyond one year. Furthermore, studies demonstrating neuropsychological decline have made use of numerous measures and varying impairment criteria, making the compilation of findings across studies challenging. Another difficulty with the current literature base is the use of traditional neuropsychological tests that are susceptible to practice effects and thus …