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Full-Text Articles in Social and Behavioral Sciences

Directed Genome Evolution To Identify Genes For Macrophage Survival By Staphylococcus Agnetis, Sonali Lakshika Anne Lenaduwe Lokuge Jul 2021

Directed Genome Evolution To Identify Genes For Macrophage Survival By Staphylococcus Agnetis, Sonali Lakshika Anne Lenaduwe Lokuge

Graduate Theses and Dissertations

Bacterial Chondronecrosis with Osteomyelitis (BCO) is a debilitating infection that negatively impacts animal welfare and costs the broiler industry billions of dollars annually. We have previously isolated Staphylococcus agnetis 908 from BCO samples obtained from broilers at the University of Arkansas research farm. This isolate can induce BCO lameness at greater than 50% in broilers exposed to the pathogen in drinking water. We found that S. agnetis 908 is capable of surviving and escaping macrophages compared to a closely related cattle isolate,1379. Through Directed Genome Evolution (DGE) we identified that this difference is at least partially associated with an alanine …


Hormone Signaling, Gene Expression, And Mitochondrial Hormone Receptor Expression In Avian Muscle (Cells), Kentu Rushadd Lassiter May 2019

Hormone Signaling, Gene Expression, And Mitochondrial Hormone Receptor Expression In Avian Muscle (Cells), Kentu Rushadd Lassiter

Graduate Theses and Dissertations

Mitochondria are vital to the proper growth and function of muscle cells since they’re responsible for the majority of ATP production used for cellular energy. Previous studies have investigated how differences in mitochondrial function affects feed efficiency (FE) in broilers phenotyped for High and Low FE. Low FE broilers have been shown to have increased levels of reactive oxygen species (ROS), thus contributing to higher levels of oxidative stress and damage seen in these birds. Global gene and protein expression studies conducted on breast muscle of the High FE and Low FE phenotypes have suggested that differences in mitochondrial function …


Growing Up In Tell El-Amarna: An Examination Of Growth And Non-Specific Stress Indicators In New Kingdom Children., Ashley Elizabeth Shidner Aug 2018

Growing Up In Tell El-Amarna: An Examination Of Growth And Non-Specific Stress Indicators In New Kingdom Children., Ashley Elizabeth Shidner

Graduate Theses and Dissertations

The health status of the subadult skeletal remains from the South Tombs Cemetery at Tell el-Amarna were assessed by examining fluctuations in childhood growth and rates of skeletal indicators of physiological stress within a biocultural framework. The long bone standardization method outlined by Goode et al. (1993) was used to compare the South Tombs cemetery’s cross-sectional growth data to subadult samples from other cemeteries during which major social, political, and economic changes were taking place. The comparative subadult samples included the HK43 cemetery from Hierakonpolis (Egypt), the African American Cemetery from Cedar Grove (Arkansas), and the St. Martin’s Churchyard from …