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Full-Text Articles in Social and Behavioral Sciences

The Value Of An Integrated Marketing Campaign To Grow Interest In Visiting The U.S. National Parks, Hermine Granberry May 2023

The Value Of An Integrated Marketing Campaign To Grow Interest In Visiting The U.S. National Parks, Hermine Granberry

Honors Theses

When the centennial celebration of the National Park Service was approaching in 2016, the National Park Service launched a two-year campaign to only commemorate the last century of NPS, but to also reconnect Americans with the parks. Ten years have passed since the initial creation of the campaign. This thesis researches the value of how another integrated marketing campaign could increase visitation to the U.S. National Parks in the future.

Through evaluating the previous Find Your Park campaign and current trends in travel and vacation, this research investigates not only future campaign ideas but also the use and incorporation of …


Catholicism Online: How The Church Is Communicating In The Visual Field, Alexandra Barfield Apr 2023

Catholicism Online: How The Church Is Communicating In The Visual Field, Alexandra Barfield

Honors Theses

ABSTRACT

Given the rise and importance of social media in the last two decades, religious institutions, especially the Roman Catholic Church, have an important place online to fulfill their mission and belief of spreading the Gospel message. Communicating this message on social media and with contemporary marketing practices is an opportunity and a challenge for churches, Catholics, and apostolates alike. In this study, I analyze a variety of Catholic-related Instagram accounts and interview individuals involved in Church management and content creation. This primary research is prefaced with secondary research exploring the status of the Catholic Church in the United States, …


The Sustainability Rhetoric Among The Spanish Fashion Companies Involved In The Rana Plaza Collapse Of 2013, Keegan Lyle May 2022

The Sustainability Rhetoric Among The Spanish Fashion Companies Involved In The Rana Plaza Collapse Of 2013, Keegan Lyle

Honors Theses

Over the last century, fashion has evolved to become a commodity that is rapidly changing and easily available. The processes that have led to this accessibility of fashion, however, have proven to be harmful to the environment and, most recently, proven to be potentially fatal for the people making the clothing. In 2013, a garment factory in Bangladesh, housing production for major global fashion brands, like Zara and The Children’s Place, collapsed following a series of negligence. The event has sparked years of awareness-raising in the public dialogue of fast fashion. As a part of the newly-developing research in sustainable …


Effective Green Marketing Strategies On Social Media: Selling Companies And Their Consumers On Investing In Carbon Offsetting And Solar Energy In 2021, Melvin Richard Springer Iv May 2022

Effective Green Marketing Strategies On Social Media: Selling Companies And Their Consumers On Investing In Carbon Offsetting And Solar Energy In 2021, Melvin Richard Springer Iv

Honors Theses

In a digital world where consumers and businesses alike care significantly about sustainability and corporate social responsibility (CSR), the success of startup companies hinges on constant, clear, and thoughtful communication. Through my research into successfully marketing such concerns on social media as well as my internship at Clearloop, I discovered some of the best ways to convince both companies and consumers that preserving the planet should be a primary concern for every environmentally conscious company. Companies that ignore their impacts on the environment are synonymous with companies doomed to fail in the 21st century. Clearloop’s model of partnering with …


The Influence Of Culture On The Accounting Profession: An Investigation Into The Implementation Of The Oecd's Inclusive Framework On Beps In The United States And Germany, Vivian Francis May 2022

The Influence Of Culture On The Accounting Profession: An Investigation Into The Implementation Of The Oecd's Inclusive Framework On Beps In The United States And Germany, Vivian Francis

Honors Theses

This research investigates the United States and Germany’s implementation of the OECD’s Inclusive Framework on BEPS and assesses the degree to which each country’s response was influenced by its culture. The objective of this research is to present a perspective on how international accounting regulations can take cultural characteristics into consideration in order to produce their desired outcomes. For the purpose of this thesis culture is defined and quantified through the framework developed by Geert Hofstede. Furthermore, this thesis investigates the relationship between the neoliberal political paradigm and the role of culture in accounting. This research uses a combination of …


Rising From The Ashes: An Analysis Of How One Infamous Promotional Event Caused A Company's Ruin And A Concept On The Future Of Influencer Experiences, Janis B. Kruger May 2022

Rising From The Ashes: An Analysis Of How One Infamous Promotional Event Caused A Company's Ruin And A Concept On The Future Of Influencer Experiences, Janis B. Kruger

Honors Theses

This thesis and its research focuses on the topic of modern influencer marketing through digital media. Throughout the thesis, traditional marketing tactics and the power of influence is discussed, and then it moves into the topic of modern advertising and the role that modern social media influencers play in reaching the consumer. The methodology behind influencer marketing is explained and consumer behavior is analyzed. The 2017 Fyre Festival promotional event is then used as an example to dissect this marketing tactic and how the event impacted the future of influencer marketing. Finally, a modern-day, hypothetical campaign based on the concept …


Communicating Through A Crisis: An Analysis Of The University Of Mississippi's Initial Covid-19 Crisis Communications, Sydney Waitley May 2022

Communicating Through A Crisis: An Analysis Of The University Of Mississippi's Initial Covid-19 Crisis Communications, Sydney Waitley

Honors Theses

This thesis, in effort to examine modern-day crisis communications, focuses on the analysis of University of Mississippi’s initial crisis communications during the COVID-19 pandemic during March 2020. The purpose of this research was to evaluate the university’s communication efforts during this crisis in order to determine the effectiveness of the University of Mississippi’s initial COVID-19 crisis communications. First, the researcher analyzed historical case studies on three notable crisis communications (the Johnson & Johnson Tylenol Crisis of 1982, the United Airlines Crisis of 2017, and the Crock-Pot Crisis of 2018). From these case studies, qualities of good crisis communications were determined …


Uncovered Magazine: A Magazine Prototype And Business Plan, Avery Bowman May 2021

Uncovered Magazine: A Magazine Prototype And Business Plan, Avery Bowman

Honors Theses

Through developing a skin care magazine prototype and business plan, this thesis aims to show how a print magazine can be successful to a young audience. By studying the history and development of both magazines and skin care and focusing on today’s industries, now is the perfect time to launch a skin care magazine. Uncovered Magazine will not only focus on filling this gap, but also will aim to empower women to find beauty in their natural skin.


Analyzing The Consumer’S Decision-Making Process To Visit Walt Disney World During The Covid-19 Pandemic, Corinne Kincade Williams May 2021

Analyzing The Consumer’S Decision-Making Process To Visit Walt Disney World During The Covid-19 Pandemic, Corinne Kincade Williams

Honors Theses

During the Covid-19 pandemic, people have had differing opinions about traveling and visiting popular destinations. This study analyzes why people decide to visit or not visit Disney World during the pandemic. To understand motivational factors affecting customers’ visit intention, a Qualtrics survey was administered through GroupMe, Disney Facebook fan pages, and MTurk. Questions applied the theory of planned behavior and additional constructs of perceived severity and perceived vulnerability to understand the reasons behind participants’ decision-making process to visit or not visit Disney World.

From the 553 responses analyzed, it was found that the most influential factors on Disney World visit …


Investigating The Relationship Between The James C. Kennedy Center And The Utilization Of The Harvard Policy Model: A Strategic Planning Process, Neely Griggs May 2021

Investigating The Relationship Between The James C. Kennedy Center And The Utilization Of The Harvard Policy Model: A Strategic Planning Process, Neely Griggs

Honors Theses

This thesis aims to understand the relationship between the James C. Kennedy Wellness Center and the utilization of the Harvard Policy Model. The Wellness Center in Tallahatchie county, Mississippi has a profound impact in the community by working to decrease the prevalence of preventable diseases, and the Wellness Center’s leadership has decided to engage in the development of a strategic plan. The researchers led the Wellness Center through the first four steps in the Harvard Policy Model of strategic planning. Through focus groups and data analysis, the Wellness Center’s vision and mission statements were re-conceptualized, the core values of the …


A Tale Of Two Companies: The Importance Of Public Relations Amidst The Shift Towards Corporate Activism, Olivia Schwab Apr 2021

A Tale Of Two Companies: The Importance Of Public Relations Amidst The Shift Towards Corporate Activism, Olivia Schwab

Honors Theses

By comparing the controversies that stemmed from Papa John’s John Schnatter and CrossFit’s Greg Glassman, some obvious public relations strategies stand out, including but not limited to understanding an audience, adapting to a changing environment, establishing a crisis communications plan, and taking controversial stands on issues close to the audience’s hearts. Most importantly though, if companies preach messages of social change, they must follow up on their stances with corrective action to do their best to help facilitate it in society.

While examining the history of corporate activism, it is clear why and how some corporations become the victims of …


Connecting Charities With Creatives: Bridging The Gap Between Local Nonprofit Organizations And University Of Mississippi Students, Natalie Pruitt Apr 2021

Connecting Charities With Creatives: Bridging The Gap Between Local Nonprofit Organizations And University Of Mississippi Students, Natalie Pruitt

Honors Theses

The purpose of this thesis is to explore the need for marketing resources among North Mississippi nonprofit organizations and apply the findings to develop and launch a website based on primary and secondary research that connects local North Mississippi nonprofit organizations with University of Mississippi graphic design, marketing, bachelor of fine arts and integrated marketing communication (IMC) students seeking experience to complete various marketing and graphic design- related tasks and develop and implement an integrated marketing plan to promote and raise awareness for the website.

Nonprofits face the challenge of allocating funds from donations to create functional and creative communications …


Community Development, Quality Of Life, And Community Well-Being: Three Fields Ripe With Opportunities For Future Research And Practice, Craig A. Talmage Sep 2020

Community Development, Quality Of Life, And Community Well-Being: Three Fields Ripe With Opportunities For Future Research And Practice, Craig A. Talmage

Community Development Practice

This perspective piece aims to spur conversations between quality of life, community well-being, and community development scholars and practitioners. The article showcases overlaps in concepts found across journals devoted to those three fields of inquiry. The major themes from those overlaps are discussed, so future directions for interdisciplinary research can be identified. The article finishes with specific attention to exploring how collaborations between the fields of quality of life (QoL), community well-being (CWB), and community development (CD) can better inform community development practice, so that community well-being and quality life can be positively shifted through evidence-based practice.


Effects Of Mind–Body Exercises On Schizophrenia: A Systematic Review With Meta-Analysis, Gao Xia Wei, Lin Yang, Kellie Imm, Paul D. Loprinzi, Lee Smith, Xiangyang Zhang, Qian Yu Aug 2020

Effects Of Mind–Body Exercises On Schizophrenia: A Systematic Review With Meta-Analysis, Gao Xia Wei, Lin Yang, Kellie Imm, Paul D. Loprinzi, Lee Smith, Xiangyang Zhang, Qian Yu

Faculty and Student Publications

© Copyright © 2020 Wei, Yang, Imm, Loprinzi, Smith, Zhang and Yu. Background: Mind–body exercises (MBEs) have been widely accepted as a complementary therapy for the patients with low exercise tolerance. Currently, the number of experimental studies investigating the effect of MBEs for improving symptoms in people with schizophrenia is increasing. However, results are inconsistent. Methods: We systematically reviewed and meta-analyzed the effects of mind–body exercises on schizophrenia. Seven electronic databases (Pubmed, Web of Science, PsycINFO, Embase, Cochrane Central Register of Controlled Trials [CENTRAL], CNKI and Wangfang) were screened through October 2019 and risks of bias of included studies were …


Impact Of Placement Of Fitbit Hr Under Laboratory And Free-Living Conditions, Hyun Chul Jung, Minsoo Kang, Nan Hee Lee, Soeun Jeon, Sukho Lee Aug 2020

Impact Of Placement Of Fitbit Hr Under Laboratory And Free-Living Conditions, Hyun Chul Jung, Minsoo Kang, Nan Hee Lee, Soeun Jeon, Sukho Lee

Faculty and Student Publications

© 2020 by the authors. Wrist-worn activity monitors have become accessible for measuring physical activities, but an activity monitor's accuracy worn at different placements is not well understood. This study aimed to examine the differences in measurements of heart rates, step counts, and calories estimated from the fitness tracker worn at different locations and the accuracy of Fitbit HR against criterion measures. Thirty-two healthy adults participated in this study. Participants wore Fitbit HR at four different locations (right proximal, distal, and left proximal, distal). Treadmill exercise consisted of five 5-min phases including slow walking and jogging. Free-living activities involved ten …


Physical Activity, Sedentary Behavior, And Sleep Quality In Adults With Primary Hypertension And Obesity Before And After An Aerobic Exercise Program: Exerdiet-Hta Study, Aitor Martinez Aguirre-Betolaza, Iñigo Mujika, Paul Loprinzi, Pablo Corres, Ilargi Gorostegi-Anduaga, Sara Maldonado-Martín Aug 2020

Physical Activity, Sedentary Behavior, And Sleep Quality In Adults With Primary Hypertension And Obesity Before And After An Aerobic Exercise Program: Exerdiet-Hta Study, Aitor Martinez Aguirre-Betolaza, Iñigo Mujika, Paul Loprinzi, Pablo Corres, Ilargi Gorostegi-Anduaga, Sara Maldonado-Martín

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: The purposes of the study were to: analyze, by objective (accelerometry) and subjective (International Physical Activity Questionnaire, IPAQ) methodologies, the physical activity (PA) and sedentary behavior (SB) in healthy adults (HEALTHY, n = 30) and individuals with primary hypertension (HTN) and overweight/obesity (n = 218); assess the effects of an aerobic exercise intervention on physical activity (PA), sedentary behavior (SB), and sleep quality in the HTN group; and evaluate the relationship between objectively measured and subjectively reported PA and SB. Methods: The measurements were performed before a 16-week exercise intervention …


Functional Training And Blood Flow Restriction: A Perspective View On The Integration Of Techniques, Marzo E. Da Silva-Grigoletto, Ezequias Pereira Neto, David George Behm, Jeremy P. Loenneke, Cauê Vazquez La Scala Teixeira Jul 2020

Functional Training And Blood Flow Restriction: A Perspective View On The Integration Of Techniques, Marzo E. Da Silva-Grigoletto, Ezequias Pereira Neto, David George Behm, Jeremy P. Loenneke, Cauê Vazquez La Scala Teixeira

Faculty and Student Publications

No abstract provided.


Acute Effects Of Kinesiology Tape Tension On Soleus Muscle H-Reflex Modulations During Lying And Standing Postures, Yung Sheng Chen, Wei Chin Tseng, Che Hsiu Chen, Pedro Bezerra, Xin Ye Jul 2020

Acute Effects Of Kinesiology Tape Tension On Soleus Muscle H-Reflex Modulations During Lying And Standing Postures, Yung Sheng Chen, Wei Chin Tseng, Che Hsiu Chen, Pedro Bezerra, Xin Ye

Faculty and Student Publications

Copyright: © 2020 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Kinesiology tape (KT) has been widely used in the areas of sports and rehabilitation. However, there is no gold standard for the tape tension used during a KT application. The purpose of this study was to examine the effects of KT application with different tension intensities on soleus muscle Hoffmann-reflex (H-reflex) modulation during lying and standing postures. Fifteen healthy university …


To Play Or Not To Play: Can An Instrument Really Impact Lip And Tongue Performance?, Robert S. Thiebaud, Takashi Abe, W. Matt Denning, Jeremy P. Loenneke, Micah J. Okerlund, Joe S.J. Ryan, Whitney Boyce, Maggie Mcbride, Jared Hernandez Jun 2020

To Play Or Not To Play: Can An Instrument Really Impact Lip And Tongue Performance?, Robert S. Thiebaud, Takashi Abe, W. Matt Denning, Jeremy P. Loenneke, Micah J. Okerlund, Joe S.J. Ryan, Whitney Boyce, Maggie Mcbride, Jared Hernandez

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. (1) Background: Increasing tongue and lip strength may help improve various speech and swallowing disorders, but it is unclear if instrumentalists who use these muscle groups for long periods of time have greater strength and endurance compared to controls. It is also unclear if instrumentalists can more accurately estimate various exercise intensities. The purpose of this study was to determine differences in lip and tongue strength and endurance between instrumentalists and non-instrumentalists (controls). A secondary purpose was to assess differences in ability to estimate various exercise intensities between the two groups. …


Analyzing The Adjustment Of American Business Expatriates In China: Professionalism, Culture And Social Support, Ramelle Mueller May 2020

Analyzing The Adjustment Of American Business Expatriates In China: Professionalism, Culture And Social Support, Ramelle Mueller

Honors Theses

This paper provides a comprehensive literature review of the American expatriate adjustment process to life in China. Additionally, online textual analysis on expatriate forum website was conducted to better understand the expatriate perspective and examines empirically the relevance of multiple factors of the expatriate adjustment process. Overarching factors include; work adjustment, general adjustment and interpersonal adjustment, which serve as the framework for this paper.


Agglomeration Economies: How “Y’Allywood” Became The New Hollywood, Joseph Dugan Walker May 2020

Agglomeration Economies: How “Y’Allywood” Became The New Hollywood, Joseph Dugan Walker

Honors Theses

Agglomeration economies have gained special attention in recent decades. With the increasing connectivity of our world, specialized regional economies are stronger now than ever before. A specific agglomeration economy that has developed in recent years is the Georgia Film Industry. This region surpassed Hollywood as the premier filming location for the first time since the early 1900s when New York was number one. This thesis analyzes the reasons why Georgia was so successful in attracting the film industry and encouraging its development by comparing infrastructure, film tax incentives, population, and labor development to that of competing states like New York, …


An Analysis Of The Skill Sets Needed To Be Successful In Nonprofit Public Relations, Hannah Williamson May 2020

An Analysis Of The Skill Sets Needed To Be Successful In Nonprofit Public Relations, Hannah Williamson

Honors Theses

The public relations industry is ever-changing, as it evolves to adapt to societal changes. Technological advancements and social media have largely contributed to changes in the way public relations professionals attempt to reach their target publics. In fact, research shows many public relations professionals do not think the term “public relations” will accurately define the work they will be doing in the near future. As the industry changes, the job duties of public relations professionals adapt as well.

This study researched the public relations industry to understand what skill sets professionals should possess in order to be successful. The study’s …


The Future’S So Bright: A Business Plan And Market Research Analysis Of Fraze, Elizabeth Lanford May 2020

The Future’S So Bright: A Business Plan And Market Research Analysis Of Fraze, Elizabeth Lanford

Honors Theses

This thesis is an overview of the creation and operation of Lindy and Liz, LLC dba Fraze. Fraze is an online boutique specializing in custom, beaded sunglasses. This thesis contains details of the founding, operation, and future of the business. The following business plan will give insights to marketing strategies, target audience demographics, and sourcing procedures.

Accompanying this business plan is market research relevant to the target market of Fraze. Part I details secondary research about the effects of social media on this target market and their consumption habits. It also contains insights about the products and marketing techniques most …


Does Extrinsic Motivation Affect Creativity Within Diverse Teams?, Gitanjali K. Viswanathan May 2020

Does Extrinsic Motivation Affect Creativity Within Diverse Teams?, Gitanjali K. Viswanathan

Honors Theses

This study analyzes the relationship between extrinsic motivation and creativity in teams. The moderation effect of functionality, openness to experience, agreeableness, conscientiousness, and diversity within a team is also considered. A survey was constructed and distributed to students within Sections 1 and 6 of the course Principles of Management at The University of Mississippi. Survey data were collected from 77 respondents and used for hierarchical regression and moderation analysis. The results of this study do not support extrinsic motivation as a significant predictor of creativity. Functionality, agreeableness, and conscientiousness each demonstrate a separate, significant interaction effect with extrinsic motivation. However, …


Imitators To Creators: The Emergence Of A Confident National Identity In Contemporary Korea As Observed Through K-Pop And Masculinity, Kaitlyn Diane Read May 2020

Imitators To Creators: The Emergence Of A Confident National Identity In Contemporary Korea As Observed Through K-Pop And Masculinity, Kaitlyn Diane Read

Honors Theses

South Korea’s national narrative has evolved from one familiar with destruction and outside control to one that can now afford to be more challenging and confrontational. Korea’s ascent to both economic and political prominence on the international landscape in record time is well established. The rapid transformation currently impacts Korean society with the country choosing to concentrate on strengthening its soft power and nation brand exporting. This thesis aims to reveal how Korea’s recently acquired position of significance on the global stage permits the Korean national identity to be assured and stimulating, in contrast with a derivative narrative once perceived …


Unanticipated Stressful And Rewarding Experiences Engage The Same Prefrontal Cortex And Ventral Tegmental Area Neuronal Populations, Alberto Del Arco, Junchol Park, Bita Moghaddam May 2020

Unanticipated Stressful And Rewarding Experiences Engage The Same Prefrontal Cortex And Ventral Tegmental Area Neuronal Populations, Alberto Del Arco, Junchol Park, Bita Moghaddam

Faculty and Student Publications

© 2020 Del Arco et al. Brain networks that mediate motivated behavior in the context of aversive and rewarding experiences involve the prefrontal cortex (PFC) and ventral tegmental area (VTA). Neurons in both regions are activated by stress and reward, and by learned cues that predict aversive or appetitive outcomes. Recent studies have proposed that separate neuronal populations and circuits in these regions encode learned aversive versus appetitive contexts. But how about the actual experience? Do the same or different PFC and VTA neurons encode unanticipated aversive and appetitive experiences? To address this, we recorded unit activity and local field …


Correlation Between Cognition And Balance Among Middle-Aged And Older Adults Observed Through A Tai Chi Intervention Program, Tao Xiao, Lin Yang, Lee Smith, Paul D. Loprinzi, Nicola Veronese, Jie Yao, Zonghao Zhang, Jane Jie Yu Apr 2020

Correlation Between Cognition And Balance Among Middle-Aged And Older Adults Observed Through A Tai Chi Intervention Program, Tao Xiao, Lin Yang, Lee Smith, Paul D. Loprinzi, Nicola Veronese, Jie Yao, Zonghao Zhang, Jane Jie Yu

Faculty and Student Publications

© Copyright © 2020 Xiao, Yang, Smith, Loprinzi, Veronese, Yao, Zhang and Yu. Background: Age-associated decline in cognition and balance may cause severe ability loss for daily living activities among middle-aged and older adults. The relationship between cognition and balance in this aging population remains to be explored. Objective: The present study Is exploratory in nature and aimed to examine the relationship between balance (both static and dynamic components) and global cognitive function among middle-aged and older adults through Tai Chi (TC) practice as a research avenue. Methods: A short-term (12 weeks) intervention of TC was conducted among middle-aged and …


A Comparison Of Motor Unit Control Strategies Between Two Different Isometric Tasks, Sunggun Jeon, William M. Miller, Xin Ye Apr 2020

A Comparison Of Motor Unit Control Strategies Between Two Different Isometric Tasks, Sunggun Jeon, William M. Miller, Xin Ye

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: This study examined the motor unit (MU) control strategies for non-fatiguing isometric elbow flexion tasks at 40% and 70% maximal voluntary isometric contraction. Methods: Nineteen healthy individuals performed two submaximal tasks with similar torque levels: contracting against an immovable object (force task), and maintaining the elbow joint angle against an external load (position task). Surface electromyographic (EMG) signals were collected from the agonist and antagonist muscles. The signals from the agonist were decomposed into individual action potential trains. The linear regression analysis was used to examine the MU recruitment threshold …


Is It Time To Rethink Our Weight Loss Paradigms?, Paulo Gentil, Ricardo Borges Viana, João Pedro Naves, Fabrício Boscolo Del Vecchio, Victor Coswig, Jeremy Loenneke, Claudio André Barbosa Apr 2020

Is It Time To Rethink Our Weight Loss Paradigms?, Paulo Gentil, Ricardo Borges Viana, João Pedro Naves, Fabrício Boscolo Del Vecchio, Victor Coswig, Jeremy Loenneke, Claudio André Barbosa

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Strategies aiming to promote weight loss usually include anything that results in an increase in energy expenditure (exercise) or a decrease in energy intake (diet). However, the probability of losing weight is low and the probability of sustained weight loss is even lower. Herein, we bring some questions and suggestions about the topic, with a focus on exercise interventions. Based on the current evidence, we should look at how metabolism changes in response to interventions instead of counting calories, so we can choose more efficient models that can account for the …


Repeat Expansion Scanning Of The Notch2nlc Gene In Patients With Multiple System Atrophy, Pu Fang, Yanyan Yu, Sheng Yao, Shuyun Chen, Min Zhu, Yunqing Chen, Keji Zou, Lulu Wang, Huan Wang, Ling Xin, Tao Hong, Daojun Hong Apr 2020

Repeat Expansion Scanning Of The Notch2nlc Gene In Patients With Multiple System Atrophy, Pu Fang, Yanyan Yu, Sheng Yao, Shuyun Chen, Min Zhu, Yunqing Chen, Keji Zou, Lulu Wang, Huan Wang, Ling Xin, Tao Hong, Daojun Hong

Faculty and Student Publications

© 2020 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association. Objective: Trinucleotide GGC repeat expansion in the 5’UTR of the NOTCH2NLC gene has been recognized as the pathogenesis of neuronal intranuclear inclusion disease (NIID). Previous studies have described that some NIID patients showed clinical and pathological similarities with multiple system atrophy (MSA). This study aimed to address the possibility that GGC repeat expansion in NOTCH2NLC might be associated with some cases diagnosed as MSA. Methods: A total of 189 patients with probable or possible MSA were recruited to screen …