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The Effects Of Gamma-Hydroxybutyrate On Response Acquisition, Sean Patrick Laraway

Dissertations

In the last 10 years, the use and abuse of the club drug gamma-hydroxybutyrate (GHB) has noticeably increased. Because GHB has only recently emerged as a drug of abuse, relatively little is known about the drug's behavioral effects, including its effects on learning. Therefore, the present study sought to characterize GHB's effects on rats' acquisition of a lever-press response using a two-lever, resetting/cancellation procedure. Under this procedure, responses on one ( reinforcement ) lever produced a single food pellet after a delay of 0, 20, or 40 s. Presses on the second ( cancellation ) lever during a delay interval …