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Social and Behavioral Sciences Commons

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Biological Psychology

George Fox University

1987

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Full-Text Articles in Social and Behavioral Sciences

Alzheimer's Disease: The Relationship Between P300 Latency And Pet Scan Ratios, Glena Lynne Needham Schubarth Andrews Jul 1987

Alzheimer's Disease: The Relationship Between P300 Latency And Pet Scan Ratios, Glena Lynne Needham Schubarth Andrews

Faculty Publications - Doctor of Psychology (PsyD) Program

The P300 component of the auditory EEG event-related potential (ERP) and Positron Emission Tomography (PET) were investigated in individuals considered to be early cases of probable Alzheimer's type dementia (PAD) and a control group of similar age. Two questions were investigated: (a) The degree to which P300 latency was sensitive to neurocognitive changes in very early stages of PAD; and (b) The relationship between P300 latency and specific areas of reduced neural functions as reflected in PET scans. A significant difference was found between PAD and normal subjects in P300 latencies, with those in the patient group having longer P300 …