Social and Behavioral Sciences Commons^™

Please Forget To Floss: Developing An Assay For Identifying Tuberculosis In Dental Calculus From The Smithsonian’S Huntington Collection (1893-1921), Soleil Young

Honors Capstone Projects - All

Tuberculosis is one of the most ubiquitous diseases in human history. Despite the long history of human interactions with the disease, tracking it retroactively is difficult because of its low rate of associated, diagnostic bony changes. Ancient DNA, also called aDNA, is a novel method for examining the presence of disease in the past. Currently, the only way to isolate tuberculosis aDNA is to drill and section bone, a method that is both invasive and expensive, limiting its use in the archaeological record. This capstone examines new ways of tracking and understanding tuberculosis in the past, utilizing the DNA trapped …