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Full-Text Articles in Physical Sciences and Mathematics
Comparing Performance Of Gene Set Test Methods Using Biologically Relevant Simulated Data, Richard M. Lambert
Comparing Performance Of Gene Set Test Methods Using Biologically Relevant Simulated Data, Richard M. Lambert
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Today we know that there are many genetically driven diseases and health conditions. These problems often manifest only when a set of genes are either active or inactive. Recent technology allows us to measure the activity level of genes in cells, which we call gene expression. It is of great interest to society to be able to statistically compare the gene expression of a large number of genes between two or more groups. For example, we may want to compare the gene expression of a group of cancer patients with a group of non-cancer patients to better understand the genetic …
A Model For Bioaugmented Anaerobic Granule, Amitesh Mahajan
A Model For Bioaugmented Anaerobic Granule, Amitesh Mahajan
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
In this study, we have created a simulation model which is concerned about digesting cellulose, as a major component of microalgae in a bioreactor. This model is designed to generate a computational model that simulates the process of granulation in anaerobic sludge and aims to investigate scenarios of possible granular bioaugmentation. Once a mature granule is formed, protein is used as an alternative substrate that will be supplied to a mature granule. Protein, being a main component of cyanobacteria, will promote growth and incorporation of a cell type that can degrade protein (selective pressure). The model developed in a cDynoMiCs …