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Articles 1 - 4 of 4
Full-Text Articles in Physical Sciences and Mathematics
Characterization Of Ovarian Cancer-Derived Extracellular Vesicles By Surface-Enhanced Raman Spectroscopy., Nina M. Culum, Tyler T. Cooper, Gilles A. Lajoie, Thamara Dayarathna, Stephen H. Pasternak, Jiahui Liu, Yangxin Fu, Francois Lagugne-Labarthet, Lynne Marie Postovit
Characterization Of Ovarian Cancer-Derived Extracellular Vesicles By Surface-Enhanced Raman Spectroscopy., Nina M. Culum, Tyler T. Cooper, Gilles A. Lajoie, Thamara Dayarathna, Stephen H. Pasternak, Jiahui Liu, Yangxin Fu, Francois Lagugne-Labarthet, Lynne Marie Postovit
Chemistry Publications
Ovarian cancer is the most lethal gynecological malignancy, owing to the fact that most cases are diagnosed at a late stage. To improve prognosis and reduce mortality, we must develop methods for the early diagnosis of ovarian cancer. A step towards early and non-invasive cancer diagnosis is through the utilization of extracellular vesicles (EVs), which are nanoscale, membrane-bound vesicles that contain proteins and genetic material reflective of their parent cell. Thus, EVs secreted by cancer cells can be thought of as cancer biomarkers. In this paper, we present gold nanohole arrays for the capture of ovarian cancer (OvCa)-derived EVs and …
Characterization Of Extracellular Vesicles Derived From Mesenchymal Stromal Cells By Surface-Enhanced Raman Spectroscopy., Nina M Ćulum, Tyler T Cooper, Gillian I Bell, David A Hess, François Lagugné-Labarthet
Characterization Of Extracellular Vesicles Derived From Mesenchymal Stromal Cells By Surface-Enhanced Raman Spectroscopy., Nina M Ćulum, Tyler T Cooper, Gillian I Bell, David A Hess, François Lagugné-Labarthet
Chemistry Publications
Extracellular vesicles (EVs) are secreted by all cells into bodily fluids and play an important role in intercellular communication through the transfer of proteins and RNA. There is evidence that EVs specifically released from mesenchymal stromal cells (MSCs) are potent cell-free regenerative agents. However, for MSC EVs to be used in therapeutic practices, there must be a standardized and reproducible method for their characterization. The detection and characterization of EVs are a challenge due to their nanoscale size as well as their molecular heterogeneity. To address this challenge, we have fabricated gold nanohole arrays of varying sizes and shapes by …
Characterization Of Extracellular Vesicles Derived From Mesenchymal Stromal Cells By Surface-Enhanced Raman Spectroscopy., Nina M Ćulum, Tyler T Cooper, Gillian I Bell, David A Hess, François Lagugné-Labarthet
Characterization Of Extracellular Vesicles Derived From Mesenchymal Stromal Cells By Surface-Enhanced Raman Spectroscopy., Nina M Ćulum, Tyler T Cooper, Gillian I Bell, David A Hess, François Lagugné-Labarthet
Chemistry Publications
Extracellular vesicles (EVs) are secreted by all cells into bodily fluids and play an important role in intercellular communication through the transfer of proteins and RNA. There is evidence that EVs specifically released from mesenchymal stromal cells (MSCs) are potent cell-free regenerative agents. However, for MSC EVs to be used in therapeutic practices, there must be a standardized and reproducible method for their characterization. The detection and characterization of EVs are a challenge due to their nanoscale size as well as their molecular heterogeneity. To address this challenge, we have fabricated gold nanohole arrays of varying sizes and shapes by …
Characterization Of Extracellular Vesicles Derived From Mesenchymal Stromal Cells By Surface-Enhanced Raman Spectroscopy., Nina M. Culum, Tyler T. Cooper, Gillian I. Bell, David A. Hess, François Lagugné-Labarthet
Characterization Of Extracellular Vesicles Derived From Mesenchymal Stromal Cells By Surface-Enhanced Raman Spectroscopy., Nina M. Culum, Tyler T. Cooper, Gillian I. Bell, David A. Hess, François Lagugné-Labarthet
Chemistry Publications
Extracellular vesicles (EVs) are secreted by all cells into bodily fluids and play an important role in intercellular communication through the transfer of proteins and RNA. There is evidence that EVs specifically released from mesenchymal stromal cells (MSCs) are potent cell-free regenerative agents. However, for MSC EVs to be used in therapeutic practices, there must be a standardized and reproducible method for their characterization. The detection and characterization of EVs are a challenge due to their nanoscale size as well as their molecular heterogeneity. To address this challenge, we have fabricated gold nanohole arrays of varying sizes and shapes by …